Cambridge Research Biochemicals Bionow BBSRC DTP Event Friday 18th March 2016 Sophie Clift Sales and Marketing Manager and Product Specialist Who are Cambridge Research Biochemicals? Custom peptide and bespoke polyclonal and monoclonal antibody manufacturer founded in Cambridge and now based in the North East (Billingham, UK). Over 36 years of expertise with a commitment to quality and the highest service standards Provider of the highest quality research tools for the pharmaceutical, biotechnology and academic life science community. Dedicated in-house customer service team and expert project management and strategic advice from PhD level Technical advisors Worlds largest range of fluorescent dyes for peptide, antibody and protein labelling and partnerships in place to provide Europium and radiolabelling services Our Peptides Highly pure peptides (up to >98%) from mg to gram scale incorporating a range of modifications and functionalities Stable isotope labelled peptides for protein quantification via mass spectrometry and tryptic digest studies. Dye labelled peptides for fluorescent work including FRET. Dyes include Alexa Fluor®, Bodipy®, Oregon Green®, CyDyes™, IRDyes®, Chromis dyes, Atto-Tec, CAL Fluor®, Quasar® and more. Multiple set peptides for epitope mapping, SARS and enzyme profiling. Typically small quantities of large numbers of sequences supplied in plate format at a lower purity. Radioactively (‘hot’) labelled peptides with Tritium (3H), Carbon-14 (14C) and Iodine-125 (125I) Our Antibodies CRB has been a provider of first class custom antibodies to the pharmaceutical industry since 1985. A range of services are offered and first rate project management and purification strategies help guarantee a high success rate. CRB’s polyclonal antibody generation service. Peptide and protein directed polyclonal antibodies, specialisms include phospho-specific and other PTM directed antibodies. CRB’s monoclonal antibody service. Full service monoclonal antibody production from antigenic prediction through to scaleup and purification. Neutralising and idiotypic antibodies are a speciality. New academic packages available. Distribution CRB also distributes various products within the UK to enable researchers to access reagents which may otherwise be difficult to source or purchase. This includes: Peptide nucleic acid (PNA) on behalf of Panagene Inc (South Korea) including custom PNA, fmoc monomers, PANArrays, PNA Telomere and centromere probes and globin reduction PNA. Europium tools on behalf of BNPS including custom labelling services, GTPase and ER kits and further assay development tools Fluorescent dye labelling kits on behalf of Cyangen NP and NIP products (haptens) from Biosearch which can be coupled to proteins to generate immunological agents for raising antibodies Why choose CRB? Excellent antibody success rate via strategies perfected over 36 years of expertise including depletion purifications, screening and antigen design. Antibody online tracker tool available, in addition to regular consultations and feedback to report all data back to the customer. Hundreds of journal articles citing CRB, customer testimonials and case studies. Customers at the University of Cambridge, CIMR, Kennedy Institute, the LMB and Children’s Hospital of Philadelphia have had work highlighted amongst others. Swift and efficient delivery of peptides (globally) including bespoke sequences tailored directly to the customers’ needs & budget, designed by our in-house experts. Customer service team in place to answer inquiries and provide updates. Strict quality control -ISO9001:2008 accreditation, home office approved housing facilities, top quality raw materials Promotional Pieces