Cancer (2005) Workplace Carcinogens – Contributing to a Deadly Disease Few diseases cause as much concern and fear as cancer, and for good reason. Despite major investment in research and treatment, the number of people contracting cancer continues to increase and many still die from cancer. The most recent statistics (2005) from the National Cancer Institute of Canada suggest that 38 per cent of Canadian women and 44 per cent of men will develop cancer during their lifetimes, and 24 per cent of women and 29 per cent of men will die from cancer. That is one out of every four Canadians. Lung cancer remains the leading cause of cancer deaths claiming 86 per cent of its victims, but incidence of cancer in other parts of the body continues to grow especially breast cancer in women and prostate cancer in men. Once considered rare to non existent, we are also seeing more and more cancer among children. Although we know a lot about workplace carcinogens – cancercausing chemicals, heavy metals, and minerals used by or produced by industry – there are still many carcinogens widely in use in industry, released into the environment, and being used in consumer products. Some experts still debate how many cancers are due to these exposures compared to other known carcinogens such as tobacco smoke, diet, and physical inactivity ignoring the fact that for many workers and their communities the exposure to carcinogens at work is much higher than that faced by the general public. There is no disagreement that the majority of cancers are preventable. Despite decades of study, debate, and public concern, Canada still does not have national or provincial policies to prevent cancer due to occupational or environmental sources, nor does it have in place the system necessary to identify exposure to these carcinogens or track the cancers that result. Despite decades of study, debate and public concern, Canada still invests very little in the prevention of cancer compared to the money spent on treatment. Recently, however, there are some signs of change. The Federal government adopted a National Strategy for Cancer Control in June 2005. A national committee struck as part of the strategy recently produced a report on Best Practices in Preventing Occupational and Environmental Cancers outlining a number of key areas where improvements are needed. Provincial cancer registries in Quebec, British Columbia, and Ontario have slowly begun to develop programs to identify and track occupational cancers. Local public health authorities have begun turn their attention to environmental health in their communities. Even the Canadian Cancer Society, perhaps the most conservative of advocacy bodies, acknowledges the significance of occupational carcinogens for workers whose jobs expose them. Much of our knowledge that these carcinogens cause cancer comes from studies done on the workers who had been exposed and were dying more frequently of cancer as a result. Today we are discovering that those same carcinogens can cause cancer at much lower levels than was seen in workplaces, and our children’s lives are at risk. The Steelworkers Union throughout its history has worked to protect its members from cancer. Throughout the ‘60s, ‘70s, and ‘80s, leading in the steel and mining industry because of the conditions there at the time, the union campaigned nationally against industrial disease and cancer in particular. Among the most well known are those of the uranium miners in Eliott Lake, Ontario, where cold war demand and unscrupulous owners required miners to unknowingly work under hazardous levels of exposure to radiation and silica resulting in a plague of cancers the effects are still being felt even now almost 15 years after the mines closed; and of the asbestos miners in Quebec and Baie Verte, Newfoundland who were never told by their employer of the hazards they faced. Our union mobilized Steelworkers across the country to convince an often unbelieving public and to force government to take action as the death toll of workers mounted, much as it did years later to change the Criminal Code of Canada to prosecute unsafe companies that kill their workers, a recommendation of the Public Inquiry into the explosion at the Westray mine that killed 26 people in 1992.. These earlier struggles lead to Royal Commissions, to new occupational health and safety laws, workers’ rights to know the hazards they face, the Workplace Hazardous Materials Information System, and major improvements in our workplaces. Since then, however, restructuring, new technology, and management policies that they created have changed substantially the exposures, reducing them in some cases and intensifying them in others. More efficient engines, for example, produce much less of the old fumes and soot that workers choked on, but much larger amounts of ultra fine particles that slip less noticed down our throats. Chemical exposures have become less visible, but no less potent. And more and more of our exposures are also in the air we breathe, in the water and land that produce our food which itself is exposed to higher amounts of and more complex chemicals. These workplace carcinogens are everywhere. When unions protested in the ‘60s, ‘70s, and ‘80s, they were told that our economy would shut down, jobs would be lost, that pollution was not the culprit, and nothing could be done about it. The union with the support of its members persisted and conditions were changed and many of those business thrived as a result. The economy did not shut down, and it is the companies that failed to change to address these concerns that had difficulty surviving. Today environmentally sustainable industries are becoming more and more a priority of the Federal and provincial government as the costs of environmental damage increases. We build on our past experiences and triumphs. All across Canada, Steelworker local unions are involved in helping past and present members address concerns about occupational cancer. Workers’ compensation boards are receiving an increasing number of claims from our efforts and recognition of these claims helps survivors cope as well as increases the pressure on government and industry to act to reduce exposures. What Is Cancer? Cancer is a general term for abnormal cell growth and describes a wide range of diseases. These diseases start from damage to the DNA (deoxyriibonucleic acid) within the nucleus of the cell. The structure of DNA provides the blueprint or plan for growth and specialization of the cell. Certain chemicals and substances can damage the structure of DNA so that it no longer controls growth and cell specialization (referred to as initiators) and/or may cause already damaged cells to mutate, triggering the uncontrollable growth of cells that characterize cancer (promoters). These chemicals and substances are called carcinogens. The term for uncontrolled growth is malignancy, and the hard, solid masses produced are tumors. Not all cancers produce tumors. Leukemia is an example of such a cancer because it develops in the bone marrow and is found through the circulatory system. As well, not all tumors are cancerous. There are many types of cancer. Carcinomas are cancers that affect the surfaces of organs, like the skin, lungs, and stomach. Sarcomas affect the muscles, cartilage, or internal portions of the organs. Neoplasm (new growth) and malignant tumor are synonyms for cancer. Metastasis occurs when clumps of cancer cells break away and spread to other parts of the body via the blood stream. This results in secondary deposits of cancer, known as metastases (standing in an abnormal place). These secondary cancers are responsible for up to 90 per cent of cancer deaths. They are not easily removed by surgery, and may spread to various locations in the body where they invade and destroy surrounding tissue. Cancer does not develop immediately on exposure to a carcinogen but only after a latency period of twenty, thirty, or even forty years or more. Cancer treatment has improved a lot over the past two decades, and survival rates have improved as a result. But make no mistake about it, cancer is a very deadly disease, and no victim and their family escape unscathed. It robs people of years from their lives, and more and more snuffs life out before it is barely underway as childhood cancers increase. How Do We Know What Causes Cancer? The science that is used to determine if something is a carcinogen is not exact. With very few exceptions, you cannot tell what caused a cancer simply by looking at it. And since cancer takes a long time to develop, scientists cannot observe cause and effect. Instead we have to rely on indirect approaches. One test or study is seldom sufficient to answer the concern. In the end we cannot be certain so public policy, prevention, and the law in Canada relies upon the precautionary principle which promotes action to protect human health in the face of uncertainty. National and international organizations exist whose job it is to review studies and tests and to provide authoritative advice on what is carcinogenic. Methods Of Identifying Carcinogens There are three methods that are commonly used to identify carcinogens: Mutagenesis Testing Animal Testing Epidemiological Studies Bacterial Testing Bacterial testing, an example of muta–genesis testing, is the observation (in a testing laboratory) of how the DNA of bacteria reacts to chemical exposure. A common example of this type of testing is the Ames test. Because nearly all proven carcinogens are also mutagens (that is, act directly upon DNA), this test screens substances for mutagenicity as an indication of potential carcinogenicity. In essence this test only proves that a substance results in a mutation of bacteria. But a growing number of reputable authorities are insisting that a mutation in bacteria can help predicts the substance’s effect on other organisms. There is also growing evidence that the bacterial testing does not recognize all carcinogens such as some chemical carcinogens (e.g., Urethane, Carbon Tetrachloride) that depend on the body’s own chemical system to cause the damage. Animal Testing These tests expose test animals to a suspect substance. The tester then watches the animal over a definite length of time for changes to its body. The animal's organs are then examined for unhealthy change. The animals we are most familiar with are laboratory rats and mice. All such animals are especially bred for research and are the same genetically. Test animals are all healthy before testing. Strict breeding is important. The experiments will use many animals and they must be very like one another. An average test could require hundreds of such animals. The real point of such a test is that a measured dose of a substance caused damage to the cell structure of a living animal. There are strong similarities in the cell structure of all animals. Whether rat or human the damage was done, and in animal testing, this is cause for concern and further investigation. To classify a substance as carcinogenic, scientists must find tumours in two or more experiments with animals. Labour’s position has long been that no new substance should enter the workplace without thorough knowledge of its toxicology and possible hazards. It is in the pretesting period where mutagenesis and animal testing play a large part. All substances in use in the workplace should be tested and retested. Any indication that a substance is carcinogenic should mean that it is removed from the workplace, or strictly regulated. This opinion, unfortunately, is not shared by those responsible for regulation of chemicals in the workplace. In many cases, we are forced to rely heavily upon a third type of study – the epidemiological study. Epidemiological Studies Epidemiology is the study of diseases in humans and the factors that influence them. Unlike bacterial and animal testing, epidemiological studies do not take place before the substance enters the workplace. They require a disease to track, and sickness or death to record. Their only preventive value is in providing evidence to get the substance out of the workplace so future workers are not injured. Epidemiological studies, when done thoroughly, can help to pinpoint the cause or causes of a health problem. They attempt to match the occurrence of a specific illness such as cancer with an exposure to a suspected carcinogen. The relationship is measured statistically and the higher the correlation, the more likely there is a causal association. The relationship is measured often by comparison to another group of workers that is considered similar except for the exposure being studied or to the general population. Because of the considerable uncertainties involved, scientists often require higher levels of statistical proof before they are willing to accept there is a reliable association. These studies are fraught with uncertainty – the exposures may not be properly measured or there may not be enough people studied to produce reliable statistical results. The process of checking the information and linking databases of worker histories with death certificates can take a long time. Nonetheless, epidemiology has proven to be a major source of information showing the link between cancer and exposure to carcinogens at work. The International Agency for Research on Cancer (IARC) There are a number of national and international agencies who critically review the scientific literature in order to make judgements on carcinogens. The most well known and recognized body is IARC and, in particular, the IARC Monograph Program which provides critical reviews of epidemiological and experimental data for chemicals, groups of chemicals industrial processes, other complex mixtures, physical and biologic agents. Between 1972 to 2003, IARC reviewed more than 880 substances of which 89 were classified as definite human carcinogens, 64 as probable, and 264 as possible human carcinogens. In that group, there are 28 definite human occupational carcinogens 27 probable human occupational carcinogens 113 possible human occupational carcinogens 18 occupations and industries that possibly, probably, or definitely entail excess risk of cancer. The IARC lists are helpful in identifying carcinogens because of the reputation of the agency that conducts the reviews. At the end of this document is a published article by Jack Semiatycki and others titled "Listing Occupational Carcinogens" which gives a detailed description of the IARC program and its results, including lists of occupational carcinogens. While the IARC lists are not exhaustive, they are an important source of information about known carcinogens. IARC is relied upon by government, workers’ compensation boards and others. Other Sources of Information There are many sources of information about carcinogens. If you have a computer and access to the internet, all you have to do is google "cancer causing chemicals" or "occupational carcinogens" or similar phrases to retrieve all sorts of information, some of it reliable and some of not. As workers, we have a legal right to know what we are exposed to at work Health and safety legislation in each province, territory, or Federal jurisdiction sets out obligations of employers to disclose information and the rights of workers and their health and safety representatives to know what they are exposed to and the limits on exposure. Most chemicals have labels and material safety data sheets (MSDS) which should include information on whether or not components of the mixture contain carcinogens. CCOHS was set up to provide free and independent information on occupational health and safety. These days not everything at CCOHS is free, but it does still provide good information. Contact CCOHS at www.ccohs.ca or by phone How do you tell if you have a problem? Are there concern about the chemicals you are using? Are there worries about your health and the health of those you work with? Do you know what you are working with? Do you notice the number of people you work with who have cancer? Do you have friends and relatives who have cancer and whether their jobs played a role? You have a right to know. Investigating Your Own Workplace There are a number of simple tools that can help you investigate whether or not you have a problem in your workplace. If your concern is that too many people who you worked with seem to be developing cancer, start making a list. As the list grows, you identify where people worked, how long, and what kind of chemicals they were exposed to. Even when you don’t know what people were exposed to, detailed descriptions of the work they did can help identify what they were exposed to. How long ago the exposures occurred are also important because cancer occurs only after a long delay called the latency period that can range from 15 to 25 years or more. Even when your workplace has little information left, there may be reported studies of similar workplaces where similar processes were used. Its is very much like being a detective and following the trail. Although we often do not realize it, we are our own best sources of information in many cases. Bringing together groups of workers often generates lots of useful information and identifies common concerns and problems that otherwise go unnoticed. A simple and useful method is called mapping which uses large drawings of bodies and workplaces to allow participants to document their health concerns as well as the work exposures collectively on a common outline. The patterns that emerge allows for further investigation to take place. Similarly if you are concerned about being exposed to carcinogens, you can compile information and utilize the joint health and safety committee as a way to convince the employer to find alternatives. There are lots of tools available to help you get started and to plan what needs to be done. Contact your local union president or staff representative for information on Steelworker area health and safety committees near you and on how to contact members of the USW Health Safety and Environment Department in your district. The Steelworker web site has lots of information and the health and safety information is growing regularly. Check us out at www.usw.ca. Provincial Federations of Labour have health and safety staff who are available to assist you as well. There are worker occupational health clinics in Alberta, Ontario, and Manitoba that provide free advice and have access to all sorts of technical resources if they are needed. Safe Exposure Levels Damage to the DNA structure of a single cell is enough to start the cancerous process. Even very brief exposure to low levels of a carcinogen can result in cancerous growth. Exposure of the lining of the lung to asbestos for as little as one day can result in a rare cancer known as mesothelioma. The only safe level of exposure to a carcinogen is no exposure at all. Of course, not every person exposed to a carcinogen will develop cancer – some coke oven workers have worked forty years or more in the mills and have died of causes completely unrelated to their work. No all smokers die of lung cancer. It is impossible; however, to predict in advance who will develop cancer and who will not. Perfect health, fitness, and strong willpower provide no defense against carcinogens. Control Measures Legislation gives workers the right to know of workplace hazards that could affect their health or safety. Information is singularly important when dealing with carcinogens. This information is available in the form of Material Safety Data Sheets, labeling, regulations, or work practices. It should include the methods of control necessary to reduce or eliminate exposure. Elimination If at all possible, carcinogenic substances should be eliminated completely from the workplace. This may be done by redesigning the work process to cut out the need for such chemicals. Redesign is a long-term measure, however, and other methods, such as retrofit, may have to be implemented in the meantime. Substitution When elimination of the substance is not possible, carcinogenic substances should be replaced with non-carcinogens. At the slab caster, replace a mold powder that contains silica with one, which contains no silica. It is important not to exchange a carcinogen for another hazardous, even if non-carcinogenic, substance. The substitution of toluene for benzene, or ceramic fibre for asbestos is the substitution of one hazard for another, somewhat less serious, hazard that still requires other control measures. Isolation Where substitution is not possible, isolation is the next consideration. Isolation reduces exposure to carcinogens by separating them from direct contact with workers. It may take the form of remotely operated systems, glove boxes, or positive pressure control booths, for example. Positive pressure in a control room keeps the contaminants outside. Local Ventilation Sometimes, the mobility of work processes, such as welding, gluing, painting and degreasing make isolation impossible. Local or immediate ventilation, coupled with protective equipment, is suitable in this case. The use of local ventilation does not restrict the need for a well-maintained general ventilation system. The local ventilation should be independent of the general system and of the closed filtering type Personal Protective Equipment Personal protective equipment must never be the first line of a worker's defense. It should be used as one part of an overall control program to provide an extra measure of protection. However, used to meet the minimum requirements of legislation, or as a stopgap arrangement for health and safety, it becomes a burden on the worker. It can also be a stumbling block to progress in decontaminating the workplace of carcinogens and other hazards. Where a regulation or work practice prescribes personal protective equipment, its use must include proper fitting, training and maintenance. Doesn't Everything Cause Cancer These Days? Carcinogens are often encountered differently in workplace settings. The chemical benzopyrene seems to be the most potent carcinogen in cigarette smoke. It is present in the fumes from roofing tar, in a concentration high enough to expose roofers to the equivalent of seven hundred cigarettes per average working day. This same carcinogen is found in coke oven emissions in a concentration equivalent to smoking one thousand cigarettes a day. On the other hand, governments prohibiting smoking from the workplace because of the risk of lung cancer for non-smokers from second-hand smoke. Yet many more workers are exposed to similar levels of "second hand" smoke form carcinogens like diesel emissions which also contains many of the same components as tobacco. Our responsibility is to help Public Health and government understand that exposure to diesel emissions and other workplace carcinogens is as serious a problem as second-hand tobacco smoke. Most provinces currently do not even have an exposure standard for diesel emissions! Effects Of Workplace Carcinogens Beyond The Gate The effects of workplace carcinogens do not stop at the workplace door. The contamination moves out into the very fabric of our society. Workers exposed to hazardous workplace substances often carry them home on clothing, hair and shoes, exposing their families to the danger. Polluted exhaust from the workplace often spews into the surrounding community and into the vegetation and waterways we depend on for life itself. Pesticides and other agricultural chemicals move from the fields and farms into the plants and stores, and from there home in our food. Effects On The Community There are growing public health concerns about environmental health – the impact of pollution, toxic chemicals and emissions on human health. As smog increases in urban areas, there are increasing warnings especially about the impact on the elderly, people with asthma and other respiratory problems, and, of course, children. While experts and government regulator are often reluctant to acknowledge the impact of pollution on cancer rates, the fact that a growing number of known occupational carcinogens are being found in the environment raises concerns. Pesticides have recently received considerable attention resulting in the ban of their use land contamination impacts on property values. Revival of community right to know and consumer education as a vehicle for community and unions to encourage their employers to address these issues proactively. This is a short list, and admittedly incomplete. To it add the economic burden on the health insurance system, over-crowding of chronic care facilities, and overwhelming pressure on the health care system in general. All of these costs and more result in part from the poisons, pollutants and contaminants generated by the workplace. Primary Prevention is the Strategy Over the past decade, the Canadian Labour Congress has argued that we need a new public policy to address the continuing problem of workplace carcinogens and toxic chemicals. We need a comprehensive approach of pollution prevention as an alternative to occupational and environmental exposure limits that have been described as "licences to poison" because of their ineffectiveness. The only option is to find an economic process to transform industries dependence on carcinogens into more environmental sustainable activities. In that process, some industries will close down, industries whose closure was inevitable because they were not fundamentally sustainable. By planning for this, an active program of job transition would lessen the blow and allow families and communities to move on with dignity. What is the Steelworkers Union fighting for? Through resolutions passed at our union’s National Policy Conference and policies adopted by the Canadian Labour Congress, the Steelworkers Union is committed to three major objectives to prevent cancer, The creation of a national exposure registry which would document toxic workplace exposures over the lifetime of a worker. To eliminate or control exposure to workplace carcinogens. To assist victims and their survivors receive just compensation. Some of the activities our union has been involved in: 1. At the local level, Steelworkers have been active in different ways from lobbying their employer to conduct epidemiological studies, to holding injured workers clinics to encourage identifying occupational cancers and assisting victims with their compensation claims. Without this local activism, the rest of our unions activities to support prevention of occupational cancer would not be effective or possible. 2. At the provincial level, Steelworker health and safety staff are part of the network of activists lobbying government, compensation boards, public health, and environment ministries for stronger laws to prevent cancer as well as effective policies for the compensation of victims and their families under workers’ compensation. Recently we have added the role of lobbying Cancer agencies and Canadian Cancer Society to make prevention a priority and to recognize importance of occupational and environmental exposures. The European Union has already developed a data base of exposures for industries based on surveys of workplaces in Finland called Carex. A pilot program to apply this database to Canada was conducted in both British Columbia and Ontario. 3. As a participant in the National Committee on Occupational and Environmental Carcinogens along with representatives of others from industry, government, non-governmental organizations, and labour, our Union is part of a comprehensive review of existing best practices for the prevention of occupational and environmental carcinogens and contributed to a set of recommendations to Federal and Provincial governments regarding a national program. 4. We work with researchers and demand that universities and government support independent research and science to identify problems and develop solutions. One of our most effective tactics has been to negotiate with our employers either through the Joint Health and Safety Committee or collective bargaining to reduce exposures to carcinogens and to conduct necessary research to identify problems and develop solutions. Some people argue that we need today to take an entirely new approach that emphasizes pollution prevention – constructing work process and products that do not require toxic and cancer causing exposures. Pollution along with other environmental challenges such as global warming and acid rain is starting to have a serious negative economic consequence for both society and business. Where do I go from here? As an active Steelworker member and member of the Canadian Labour Congress, you have access to as wealth of materials and opportunities for training and education. Contact your local union president or staff representative for information. Our union has opportunities for involvement and networking among health and safety activists at a regional, district, and national level. Check us out on the web at www.usw.ca. Take this information back to where you work and see what others are willing to do.