• Today- Start Chapter 9 • Announcements Chapter 8 quiz on WebCT is due Sunday, March 19. Do it before you leave for spring break. No excuses !!!!! Final Day to drop a class is Friday, March 17. Grade on Exam 2 Score (out of 70) A 70 (or more) -63 B 62-56 C 55-49 D 48-42 F Below 42 Warm up Questions 1, 2, 3 1. What structure is this? 2. What does the symbol Pi or P represent? 3. What does ADP stand for? Chapter 9 Pictures Carbon and Energy Flow CO2 + H2O Photosynthesis Carbs Proteins Lipids + O2 Cellular (Aerobic) Respiration (ATP Produced) Fig 9.2 Digestion + Cellular Respiration = ATP Production Frig 8.11 Why do cells need ATP? Oxidation releases energy which is stored as ATP oxidation Energy Released organic molecules (from food) Simpler waste products (CO2 +H2O) ATP (energy storage molecule) + Heat EA Questions 9.1-9.2 Digestion Fig 9.19 Cellular Respiration Fig 9.6. Glycolysis Fig 9.6 Formation of Acetyl CoA and the Citric Acid Cycle Acetyl CoA Formation Fig 9.6 Electron Transport and Chemiosmosis Acetyl CoA Formation Fig 9.7 Substrate-level Phosphorylation Fig 9.14. Oxidative Phosphorylation = Making ATP using Electron Transport and Chemiosmosis NADH + FADH2 Fig 9.8 Overview of Glycolysis Energy Investment Phase (2 Glyceraldehyde-3-P) Energy Payoff Phase Glycolysis: Energy Investment Phase 2 Glyceraldehyde-3-P Energy Investment Phase (2 Glyceraldehyde-3-P) Energy Payoff Phase Redox Reactions 2 electrons and 1 proton = hydride ion = H-1 NAD is an electron carrier in the cell. Step 1 of the Energy Payoff Phase 2 Glyceraldehyde-3-Phosphates Oxidation of sugar 2 e- removed from each glyceraldehyde-3 - P electrons “Redox” reaction Reduction of NAD Each NAD+ has gained 2 e- in the form of “H-” =hydride ion. (reduction-oxidation) Produces NADH electrons Glycolysis: Energy Payoff Phase 2 Glyceraldehyde-3-P Glycolysis Summary Glucose Energy Investment Phase Energy Payoff Phase 2 ADP 2 ATP 4 ADP 4 ATP 2 NAD+ 2 NADH 2 Pyruvate Glucose 2 ADP + 2 Pi 2 NAD+ 2 Pyruvate + 2 H20 2 ATP 2 NADH Question 9.3 Fig 9.6 Formation of Acetyl CoA Acetyl CoA Formation Fig 9.10 Formation of Acetyl CoA Fig 9.6 Citric Acid Cycle Acetyl CoA Formation Fig 9.12 Citric Acid Cycle Question 9.5 Glucose is completely oxidized to CO2 • Glycolysis: glucose (6-C) => 2 pyruvate (3-C) Breathe out • Formation of Acetyl CoA 2 pyruvate (3-C) => 2 Acetyl CoA (2-C) + 2 CO2 Breathe out • Citric Acid Cycle 2 Acetyl CoA (2-C) => 4 CO2 Fig 9.6 Electron Transport and Chemiosmosis Acetyl CoA Formation Fig 9.15: Electron transport and chemiosmosis Intermembrane Space (pH 7) Inner membrane Matrix (pH 8) Chemiosmosis (Refer to figure in handout. We will use only NADH as an example.) Fig 9.15 IV I III Chemiosmosis Electron Transport Chain IV I III H+ H+ H+ Chemiosmosis Question 9.5 Chemiosmosis H+ H+ pH 7 pH 8 Chemiosmosis Fig 9.14. Oxidative Phosphorylation = Making ATP using Electron Transport and Chemiosmosis NADH + FADH2 Question 9.6 Fig 9.18 Fermentation Overview Fig 9.17a Alcohol Fermentation Fig 9.17b Lactic Acid Fermentation Most Eukaryotes C. botulinum produces the potent nerve toxin that causes botulism. Question 9.7