Anesthesia for Trauma Christopher DeSantis, MD Anesthesiology CA-3 Boston University Medical Center October 12, 2006 Faculty Advisor: Dr. Lopes Anesthesia for Trauma Trauma is the leading cause of death between the ages of 1 and 45 In the US preventable deaths decreased from 13% to 7% over the past decades because of more efficient systems of trauma care Anesthesia Care Airway and Resuscitation in Emergency Department Operating Room Care Management in Intensive Care Unit Prioritizing Trauma Care Do you know your ABC’s ? Prioritizing Trauma Care ABCDE Airway Vocal Response, Auscultation Chin Lift, Bag-Valve-Mask, 100% O2, Intubation, Cricothyriodotomy, Tracheostomy Breathing Pulse Oximetry, Arterial Blood Gas, CXR Mechanical Ventilation, Tube Thoracostomy Prioritizing Trauma Care Circulation Vital Signs, Capillary Refill, Response to Fluid Bolus, CBC, Coagulation Studies, FAST, X-Ray Adequate IV Access, Fluid Bolus, Pressure to Open Wounds, Thoracotomy, Transfusion, Surgery Neurologic Disability GCS, Motor/Sensory Exam, Head, Neck, and Spine CT, Cervical Spine Films Support Oxygenation/Perfusion, ICP Monitoring Prioritizing Trauma Care Exposure and Secondary Survey Laboratory Studies, ECG, Plain Films, CT scan, Detailed History and Physical Exam Removal of all Cloths, Detailed Review of all Laboratory and Radiographic Findings Airway/Breathing Verification of adequate airway and acceptable respiratory mechanics is of primary importance Hypoxia is the most immediate threat to life Inability to oxygenate a patient will lead to permanent brain injury and death within 5 to 10 Minutes Airway obstruction Direct injury Face, Mandible, or Neck Hemorrhage Pharynx, Sinuses, and Upper airway Diminished Consciousness Traumatic Brain injury, Intoxication, Analgesic medications Aspiration Gastric contents, Foreign body Misapplication of Airway/Endotracheal Tube Esophageal Intubation Inadequate Ventilation Diminished Respiratory Drive Traumatic Brain injury, Shock, Intoxication, Hypothermia, Over Sedation Direct Injury Cervical Spine, Chest Wall, Pneumo/Hemothorax, Trachea, Bronchi, Pulmonary Contusion Aspiration Gastric contents, Foreign body Bronchospasm Smoke, Toxic Gas Inhalation Indications for Endotracheal Intubation Cardiac or Respiratory Arrest Respiratory Insufficiency Airway Protection Deep Sedation or Analgesia General Anesthesia Transient Hyperventilation Space Occupying Intracranial Lesion/Increased ICP Delivery of 100% O2 Carbon Monoxide Poisoning Facilitation of Diagnostic Workup Uncooperative or Intoxicated Patient Prophylaxis against Aspiration Trauma patients are always considered to have full stomach Ingestion of food or liquids before injury Swallowed blood from oral or nasal injury Delayed gastric emptying Administration of liquid contrast medium Reasonable to administer nonparticulate antacid prior to induction Cricoid pressure/Sellick Maneuver should be applied continuously during airway management Rapid Sequence Induction Avoidance of ventilation between administration of medication and intubation Cervical Spine Injury Trauma Patients No Radiological Studies Alert, Awake, and Oriented No Neurological Deficits No Distracting Pain MRI Cervical Spine Neck Pain Cervical Tenderness to Palpation Cervical Spine Injury All Other Trauma Patients Lateral radiograph of cervical spine Anteropostererior spinous process C2-T1 Open mouth odontoid view Axial CT with reconstruction Regions of questionable injury Inadequate visualization Protection of the Cervical Spine All blunt trauma victims should be assumed to have an unstable cervical spine until proven otherwise Direct laryngoscopy causes cervical motion and the potential to exacerbate spinal cord injury An “uncleared” cervical spine mandates In-line Stabilization (Not Traction) The front of the cervical collar may be removed for greater mouth opening and jaw displacement Protection of the Cervical Spine Emergency Awake Fiberoptic Intubation Requires less manipulation of the neck Generally very difficult Airway Secretions Hemorrhage Rapid Desaturation Lack of Patient cooperation Induction of Anesthesia Propofol/Thiopental Vasodilator, Negative Inotropic effect May Potentate hypotension/Cardiac Arrest Etomidate Increased cardiovascular stability Ketamine Direct myocardial depressant Catecholamine release Hypertension/Tachycardia Midazolam Reduced Awareness Hypotension Scopolamine (Tertiary Amine) Inhibits memory formation Muscle relaxants alone Recall of Intubation/Recall of Emergency procedures Neuromuscular Blocking Drugs Succinylcholine Fastest onset <1 min Shortest Duration5-10 min Potassium increase 0.5-1.0mEq/L Potassium increase >5mEq/L After 24 hours Safe in acute airway management Burn Victims Muscle Pathology Direct Trauma Denervation Immobilization Increase intraocular pressure Caution in patients with ocular trauma Increase ICP Controversial in head trauma Circulation Hemorrhage is the next most pressing concern Ongoing blood loss will be fatal in minutes to hours Shock is presumed to be a consequence of hemorrhage until proven otherwise Symptoms of Shock What are the symptoms of shock ? Symptoms of Shock Pallor Diaphoresis Agitation or Obtundation Hypotension Tachycardia Prolonged Capillary Refill Diminished Urine Output Narrow Pulse Pressure Early Resuscitation Maintain SBP at 80-100 mm Hg Maintain Hematicrit at 25-30% Maintain PT/PTT in normal range Maintain Platelet count > 50,000 Maintain Normal serum ionized calcium Maintain core temperature > 35°C Prevent increase in serum lactate Prevent Acidosis Intravenous Access Order of Desirability Large-bore (16g or greater) antecubital vein Other large-bore peripheral veins Subclavian vein Femoral vein Internal jugular vein (Requires removal of cervical collar and neck manipulation) Intraosseous (Tibia or distal end of femur) Fluid Infusion System Active fluid administration up to 1500 ml/min Compatible with crystalloid, colloid, RBC, plasma, washed/salvaged blood (Not platelets) Reservoir allows for mixing of products Controlled temperature (38°-40°C) Able to pump through multiple IV lines Fail safe detection system to prevent infusion of air Accurate recording of volume administered Portable to travel with patients between units Risks of Aggressive Volume Replacement Increased blood pressure Decreased blood viscosity Decreased hematocrit Decreased Clotting factors Greater transfusion requirements Electrolyte imbalance Direct immune suppression Premature reperfusion Glasgow Coma Score What is the Glasgow Coma Score ? Glasgow Coma Score Eye Opening Response 4=Spontaneous 3=To Speech 2=To Pain 1=None Verbal Response 5=Oriented to Name 4=Confused 3=Inappropriate Speech 2=Incomprehensible Sounds 1=None Motor Response 6=Follows Commands 5=Localizes to Pain 4=Withdraws from Pain 3=Abnormal Flexion (Decorticate Posturing) 2=Abnormal Extension (Decerebrate Posturing) 1-None Traumatic Brain Injury Anesthetic Management Avoidance of Hypoxemia Intubation Airway protection Controlled Hyperventilation Uncooperative/Combative Patient GCS < 8 Control Hemodynamics Avoid Hypotension Fluid Administration Vasopressors Arterial Line Traumatic Brain Injury Management of Cerebral Circulation Hyperventilation PaCO2 at 35 mmHg PaCO2 at 30 mmHg for episodes of elevated ICP Mannitol 0.5-1g/kg Barbiturate Traumatic Brain Injury Temperature Avoid Severe Hypothermia Do not warm aggressively Hyperthermia increases CMRO2 Position Therapy Elevation of Patients Head Facilitate venous drainage Lower ICP Improved Ventilation/Perfusion