honors biology Ch. 10 objectives Molecular Biology of the Gene Opening Essay: Explain how a herpes virus invades a cell and causes disease. The Structure of the Genetic Material 10.1 Describe the experiments of Griffith, Hershey, and Chase, which supported the idea that DNA was life’s genetic material. 10.2–10.3 Compare the structures of DNA and RNA. 10.3 Explain how Chargaff’s rules relate to the structure of DNA. DNA Replication 10.4 Explain how the structure of DNA facilitates its replication. 10.5 Describe the process of DNA replication. Describe the mechanisms that correct errors caused by environmental damage or errors from replication. The Flow of Genetic Information from DNA to RNA to Protein 10.6 Describe the locations, reactants, and products of transcription and translation. 10.7–10.8 Explain how the “languages” of DNA and RNA are used to produce polypeptides. 10.9 Explain how RNA is produced. 10.10 Explain how eukaryotic RNA is processed before leaving the nucleus. 10.11 Relate the structure of tRNA to its functions in the process of translation. 10.12 Describe the structure and function of ribosomes. 10.13 Explain how translation begins. 10.14 Describe the step-by-step process by which amino acids are added to a growing polypeptide chain. 10.15 Diagram the overall process of transcription and translation. 10.16 Describe the major types of mutations, causes of mutations, and possible consequences. Microbial Genetics 10.17 Compare the lytic and lysogenic reproductive cycles of a phage. 10.18 Compare the structures and reproductive cycles of an enveloped RNA virus and a herpesvirus. 10.19 Describe three processes that contribute to the emergence of viral disease. 10.19 Explain why RNA viruses tend to have an unusually high rate of mutation. 10.20 Explain how the AIDS virus enters a host cell and reproduces. 10.21 Describe the structure of viroids and prions and explain how they cause disease. 10.22 Define and compare the processes of transformation, transduction, and conjugation. 10.23 Describe the roles of bacterial F factors. Define a plasmid and explain why R plasmids pose serious human health problems. Key Terms adenine (A) AIDS anticodon bacteriophage capsid codon conjugation cytosine (C) DNA ligase DNA polymerase double helix emerging virus exon F factor genetic code guanine (G) HIV Mrs. Loyd cloyd@waukee.k12.ia.us intron lysogenic cycle lytic cycle messenger RNA (mRNA) molecular biology mRNA mutagen mutagenesis mutation nucleotide P site phage plasmid polynucleotide prion promoter prophage R plasmid reading frame retrovirus reverse transcriptase ribosomal RNA (rRNA) RNA polymerase RNA splicing rRNA semiconservative model start codon stop codon Page 1 of 2 http://loydbiology.weebly.com sugarphosphatebackbon e terminator thymine (T) transcription transduction transfer RNA (tRNA) transformation translation triplet code tRNA uracil (U) viroid virus 7/12/2016 http://www.mybiology.com Student Media The Structure of the Genetic Material Activity: The Hershey-Chase Experiment (10.1) Activity: Phage T2 Reproductive Cycle (10.1) Activity: DNA and RNA Structure (10.3) Activity: DNA Double Helix (10.3) BLAST Animation: Hydrogen Bonds in DNA (10.3) BLAST Animation: Structure of Double Helix (10.3) DNA Replication Activity: DNA Replication (10.5) Process of Science: What is the Correct Model for DNA Replication? (10.4) The Flow of Genetic Information from DNA to RNA to Protein BioFlix: Protein Synthesis (10.6) MP3 Tutor: MP3 Tutor: DNA to RNA to Protein (10.6) Activity: Transcription (10.9) Activity: Translation (10.14) Process of Science: How Are Nutritional Mutations Identified? (10.6) Process of Science: How Do You Diagnose a Genetic Disorder? (10.16) BLAST Animation: Roles of RNA (10.9) BLAST Animation: Transcription (10.9) BLAST Animation: Translation (10.14) Microbial Genetics Activity: Phase Lysogenic and Lytic Cycles (10.17) Activity: Simplified Reproductive Cycle of a DNA Virus (10.18) Activity: Retrovirus (10.20) Process of Science: Why Do AIDS Rates Differ Across the US? (10.19) Process of Science: What Causes Infections in AIDS Patients? (10.20) Process of Science: How Can Antibiotic-Resistant Plasmids Transform E. coli? (10.23) Discovery Channel Video Clip: Emerging Diseases (10.19) BLAST Animation: AIDS Treatment Strategies (10.20) BLAST Animation: HIV Structure (10.20) BLAST Animation: Plasmid (10.23) Mrs. Loyd cloyd@waukee.k12.ia.us Page 2 of 2 http://loydbiology.weebly.com 7/12/2016 http://www.mybiology.com