LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
B.Sc. DEGREE EXAMINATION – PLANT BIOLOGY & BIOTECHNOLOGY
FIFTH SEMESTER – NOV 2006
AE 07
PB 5401 - MEDICAL MICROBIOLOGY
(Also equivalent to PBB 401)
Date & Time : 03-11-2006/9.00-12.00
Dept. No.
Section-A
Max. : 100 Marks
(20 marks)
Answer all questions
I. Choose the correct answer:
(5x1=5 marks)
01. Match A. Jenner B. Koch C. Widal D. Calmette with
i. Typhoid ii. Variola iii. TB iv. Cholera
a. A-i, B-iv, C-iii, D-I
b. A-ii, B-i, C-iv, D-iii
c. A-ii, B-iv, C-i,
D-iii
d. A-ii, B-iii, C-iv, D-i
02. Statement A: Griseofulvin is obtained from penicillium.
Statement B: It is an antibacterial antibiotic.
a. Statement A is correct, but Statement B is incorrect
b. Statement A is incorrect, but Statement B is correct
c. Both A and B are correct
d. Both A and B are incorrect
03. The most prominent resident flora of eye is :
a. Corynebacterium xerosis
b. Vibrio cholera
c. Corynebacterium diphtheriae
d. E.coli
04. Histoplasmoses is caused by a :
a. virus
b. bacterium
c. actinomycete
d. fungus
05. Quinine is associated with
a. rabies
b. syphilis
c. malaria
d. tetanus
II. State whether True or False.
(5x1=5 marks)
06. Sterilization involves the destruction of all forms of microbial life.
07. The term ‘chemotherapy’ was coined by Lister.
08. Intact skin is a good example of internal defense mechanism.
09. Chicken pox is caused by varicella zoster virus.
10. Tetanus is a communicable disease.
III. Complete the following :
(5x1=5 marks)
11. Application of _________ radiation to sterilize biological materials is called ______
stenlization.
12. ________ __________ tests are used to test the susceptibility of pathogens to drugs.
13. ______ of ________ refers to the route taken by pathogenic microbes to gain
entrance to hosts.
14. ________ _________ refers to fungal, infections which affect deeper systems of our
body.
15. Typhus fever is an example of ________ _______ disease.
IV. Answer the following each within 50 words.
(5x1=5 marks)
16. Enumerate any four characteristics of an ideal antimicrobial chemical agent.
17. Mention the source and mode of action of Nystatin.
18. What is relative immunity?
19. Write down any two symptoms of Hepatitis.
20. Name any two genera which cause dermatophytic infection in man.
Section-B
Answer any five questions, each within 350 words.
(5x8=40 marks)
21. Compare the efficiency of moist heat and dry heat. Add a note on osmotic pressure
used to control microbes.
22. Write about the mode of action of sulphonamides.
23. Discuss any one antigen-antibody reaction along with its applications.
24. Explain the morphological, cultural, physiological and antigenic characters of
Mycobacterium tuberculosis.
25. Write about the disease cycle of malaria.
26. Expand the following with a footnote each :
i. Eto
ii. PABA
iii. TPCF
iv. DPT
27. Distinguish between :
i. Bactericidal and Bacteriostatic agent
ii. Penicillin and Streptomycin (source)
iii. Endemic and Pandemic disease
iv. Tetanus and Rabies (causal organism)
28. Define the following :
i. Fumigation
ii. Chemotherapy
iii. Transient Flora
iv. Amoebiasis
Section-C
Answer the following, each within 1500 words only.
(2x20=40 marks)
29. a. Give an account of control of microbes by dry heat, radiation, phenols and heavy
metals.
or
b. Discus the causal organism, symptoms, treatment and control of cholera.
30. a. Compare and contrast Syphilis and Gonorrhoea..
or
b. Write short notes on
i. Gaseous chemosterilizers
ii. Properties of Antibiotics
iii. Endotoxin
iv. Dermatophytoses
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