LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034 B.Sc. DEGREE EXAMINATION – ADVANCED ZOOLOGY & BIOTECH. SIXTH SEMESTER – APRIL 2012 AZ 6601 - BIOINFORMATICS Date : 18-04-2012 Time : 1:00 - 4:00 Dept. No. Max. : 100 Marks PART – A Answer ALL questions. All questions carry equal marks: (10 x 2 = 20 marks) Define / Explain the following: 1. HTML 6. Designer drugs 2. Operating system 7. WWW 3. ISDN 8. Gene therapy 4. EMBL 9. Optimal alignment 5. PCR 10. String similarity PART – B Answer any FOUR questions. All questions carry equal marks: (4 x 10 = 40 marks) 11. Write an account on sequence homology analysis and predictive function. 12. Elaborate the characteristics of Algorithms. 13. Discuss the data mining and knowledge discovery. 14. Relate the significance of multiple alignment and phylogeny tree construction. 15. Write the common multiple alignment methods. 16. Explain the parametric sequence alignment. PART – C Answer any TWO questions. All questions carry equal marks: 17. Write an essay on Data base management system. 18. Discuss the protein sequence data bases and SWISS - PROT. 19. Describe the following: a) BMRB database. 20. Explain the DNA finger printing. $$$$$$$ b) BLOCKS database. (2 x 20 = 40 marks)