THERMOREGULATION Control of body temperature © 2008 Paul Billiet ODWS Core temperature The core temperature of the human body is 37°C The core of the human body includes the organs of the thorax, abdomen and the head This is where the vital organs are located Their enzyme systems must operate in optimum conditions The periphery of the body can withstand some deviation from the core temperature © 2008 Paul Billiet ODWS Heat loss and heat gain The body must balance its heat budget Heat is gained: by conduction from warm air surrounding the body by the body’s metabolic activity which generates heat e.g. when muscle move Heat is lost: by conduction and radiation to cold air (or water) by evaporation of sweat from the body surface (c.f. properties of water) Humans can also affect their body temperature by changing their behaviour e.g. wearing different clothes, seeking shade © 2008 Paul Billiet ODWS Maintaining the body temperature Keeping warm Staying cool Increased insulation, subcutaneous fat reduces the conduction of heat from the body Increase blood flow to skin, increases conduction and radiation of heat from the body Reduced sweating decreases evaporation Increased sweat secretion, increases evaporation Increased shivering, increases heat produced by muscle tissue 2 to 5 times Reduced activity © 2008 Paul Billiet ODWS Core body temperature >37°C Thermoreceptors Hypothalamus nerves Muscles reduce activity Sweat glands increase secretion Muscles of skin arteriole walls relax Skin arteries dilate More blood to the skin. More radiation & conduction of heat More water covers the skin. More evaporation Less heat generated © 2008 Paul Billiet ODWS NEGATIVE FEEDBACK Thermoreceptors Core body temperature >37°C Thermoreceptors Blood temperature Muscles of skin arteriole walls relax nerves Hypothalamus Sweat glands increase secretion Muscles reduce activity © 2008 Paul Billiet ODWS Body loses heat Return to 37°C Core body temperature <37°C Thermoreceptors Hypothalamus nerves Muscles shivering nerves Sweat glands decrease secretion Muscles of skin arteriole walls constrict Less water covers the skin. Less evaporation More heat generated © 2008 Paul Billiet ODWS Skin arteries constrict Less blood to the skin. Less radiation & conduction of heat NEGATIVE FEEDBACK Thermoreceptors Blood temperature Muscles of skin arteriole walls constrict nerves Core body temperature <37°C Thermoreceptors Sweat glands decrease secretion Hypothalamus nerves © 2008 Paul Billiet ODWS Muscles shivering Body loses less heat Body gains heat Return to 37°C