NAME_______________________________
VIROLOGY
TEST #3-sample2
R. H. REEVES
THE FIRST TWENTY QUESTIONS ARE WORTH TWO POINTS EACH.
THERE IS
ONLY ONE CORRECT ANSWER. PLEASE CIRCLE THE CORRECT LETTER OR PLACE
THE CORRECT LETTER JUST TO THE LEFT OF THE QUESTION NUMBER.
1.
VIRUSES WITH CIRCULAR VIRION GENOMES INCLUDE
A.
HEPATITIS B VIRUS AND HERPES SIMPLEX VIRUS-1
B.
SMALLPOX VIRUS AND PARVOVIRUS B19
C
HUMAN PAPILLOMA VIRUS-16 AND HEPATITIS B VIRUS
D.
SMALLPOX VIRUS AND AAV-2
E.
SIMIAN VIRUS-40 AND HUMAN ADENOVIRUS-12
2.
THESE VIRUSES HAVE A SINGLE ORF
A.
AAV-2 & HUMAN PAPILLOMAVIRUS-16
B.
HUMAN PAPILLOMAVIRUS-16 & HEPATITIS D VIRUS
C.
HEPATITIS D VIRUS & TOBACCO NECROSIS SATELLITE VIRUS
D.
TOBACCO NECROSIS SATELLITE VIRUS & PARVOVIRUS B19
E.
PARVOVIRUS B19 & HEPATITIS D VIRUS
3.
TRANSFER-RNA IS FOUND IN THE VIRION OF
A.
POLYOMAVIRUS
B.
HERPES SIMPLEX VIRUS
C
MOLLUSCUM CONTAGIOSUM VIRUS
D.
ROUS SARCOMA VIRUS
E.
PARVOVIRUS B19
4.
THE GENOME OF ADENOVIRUS-2
A.
IS CIRCULARLY PERMUTED
B.
HAS A Vpg ON EACH 3’-END
C.
BOTH OF THE ABOVE
D.
NEITHER OF THE ABOVE
5.
ADENOVIRUSES
A.
CAUSE WARTS
B.
CAUSE ACUTE RESPIRATORY DISEASE
C.
BOTH OF THE ABOVE
D.
NEITHER OF THE ABOVE
6.
IN ROUS SARCOMA VIRUS PROGRAMMED FRAMESHIFTING IS REQUIRED
FOR THE EXPRESSION OF
A.
gag GENES
B.
env GENES
C.
BOTH OF THE ABOVE
D.
NEITHER OF THE ABOVE
7.
THESE TWO DNA VIRUSES DO NOT HAVE LIPID ENVELOPES
A.
B.
C.
D.
E.
8.
AAV-2 AND CYTOMEGALOVIRUS
SV-40 AND VACCINIA VIRUS
EPSTEIN-BARR VIRUS AND VARIOLA VIRUS
ADENOVIRUS-2 AND PARVOVIRUS B19
PAPILLOMAVIRUS AND MONKEYPOX VIRUS
LINEAR DNA IS FOUND IN THE VIRION OF
A.
HEPATITIS D VIRUS
B.
PAPILLOMAVIRUS
C
SV-40
D.
AAV-2
E.
ROUS SARCOMA VIRUS
KEY FOR QUESTIONS 14-20.
THERE IS ONLY ONE CORRECT ANSWER BUT
EACH KEY WORD MAY BE USED MORE THAN ONCE.
A.
B.
C.
D.
E.
F.
G.
I.
SMALLPOX VIRUS
POLYOMAVIRUS
PARVOVIRUS B19
EPSTEIN-BARR VIRUS
HUMAN PAPILLOMAVIRUS-16
HEPATITIS B VIRUS
HIV-1
HUMAN ADENOVIRUS-2
_____14.
IT HAS A tat AND A rev GENE
_____15.
HAS A "LOOSE-FITTING ENVELOPE" SURROUNDING ITS
ICOSAHEDRAL CORE
_____18.
CONTAINS A WEDGED-SHAPED CORE
_____19.
ITS DENATURED GENOME IS A SINGLE-STRANDED CIRCLE
VIRION NUCLEIC ACID
NUCLEIC ACID
STRANDEDNESS
HIV-1
_____
SINGLE
_______
VARIOLA V
_____
___________
LINEAR
PARVOVIRUS
DNA
FORM
___________
ENDS
__________
CROSS-LINKED, TRs
________
___________
HEPATITIS D V
_____
___________
________
___________
PAPILLOMAVIRUS
_____
DOUBLE
________
___________
21.
DESCRIBE THE SIMILARITIES AND DIFFERENCES AMONG 1. RNA
VIRUSES,
2. RNA SATELITTE VIRUSES, 3.
SATELLITE RNAs
AND 4.
VIROIDS. BE SURE TO INCLUDE PROPERTIES SUCH AS
REQUIREMENT FOR
HELPER VIRUS AND WHETHER THE RNA IS ENCAPSIDATED,
AMONG OTHERS. (A TABLE IS SUGGESTED.)
23.
NAME THREE ENZYME ACTIVITIES ENCODED BY THE HIV-1 GENOME
(FOUR HAVE BEEN DETECTED). DESCRIBE THE MAIN FUNCTION OF
EACH AND AT WHAT PART OF THE HIV-1 LIFE CYCLE THEY ACT.
WHICH TWO ENZYMES ARE THE TARGETS FOR ANTI-RETROVIRAL
DRUGS?