Topic: Immunity Aim: Describe the structure and role of pathogens in causing disease. Do Now: Take out your Immune System reading notes and your skeletal system picture to finish labeling. HW: Castle Learning Skeletal, Muscular and Immune Systems due Tuesday, March 22nd Do Now: With your 3:00 partner, identify and describe the function of structures A, B and C in the diagram. A – Skeletal muscle •Attach to bone to aid in movement B - Ligament •Connect bone to bone C - Tendon •Connect muscle to bone Identify the name of organisms that cause disease. • PATHOGENS • Prefix??? –From Greek pathos "disease” • Suffix??? –From French -génique "producing" Examples of pathogens??? Schistosoma mansoni is a major parasitic pathogen that causes schistosomiasis. You can become infected when your skin comes in contact with contaminated freshwater. Schistosomiasis accounts for greater than a ¼ of a million deaths per year. These not found in the U.S. Why? Within days after becoming infected, they may develop a rash or itchy skin. Within 12 months of infection, symptoms may develop including fever, chills, cough, and muscle aches. Symptoms of chronic schistosomiasis include: abdominal pain, enlarged liver, blood in the stool or blood in the urine, problems passing urine, and increased risk of bladder cancer. 1. Which 3 • Integumentary systems • Respiratory provide the • Digestive body with its first line of defense against pathogens? 2. Identify • White blood cells what is produced when foreign materials get past the 1st line of defense. 3. Identify • Antigen the protein on pathogens that your body does not recognize. 4. Identify • Antibodies what attaches to the antigen on the pathogen. 1. Identify the labeled structures. 2. Where are antigens located? On the pathogen 3. Describe the shape of A Pathogen an antibody. Y shape 4. Describe the relationship Antigen B between an antigen and an antibody. Antibody C Shapes match 5. Identify other substances in the body have that this same type of relationship. Neurotransmitters and receptors Hormones and receptors 5. Identify • B-lymphocytes the type of white blood cell that produces antibodies. • Resistance to a sickness 6. Describe (DISEASE) immunity. 7. Identify • Active immunity the 2 types • Passive immunity of immunity. 8. Identify the type of immunity that occurs when antibodies are NOT produced by the person’s own body but given to the body from another source. • Passive immunity 9. How can a person develop PASSIVE immunity? 9. How can • New born baby only a person have antibodies from develop mother: PASSIVE – during pregnancy immunity? – through breast milk • Receiving antibodies 10. Identify the type of immunity developed when the body produces its own antibodies. • Active Immunity 11. Identify the 2 ways you can develop ACTIVE immunity. • When your body 11. FIGHTS against any Identify specific PATHOGEN the 2 ways you can your have developed develop antibodies against ACTIVE • By receiving a VACCINE immunity. 12. • Small amounts of Identify weakened or dead what makes pathogens. up a vaccine. 13. Explain • B cells are called into action to create why a antibodies as is you vaccine were fighting a real causes illness. active immunity. Memory Cells • Another type of lymphocyte • Also produced when pathogens enter the body. • Remain in the blood ready the defend against invasion of the same pathogen at another time Let’s summarize… 1. What is a pathogen? 2. Identify the body’s 1st line of defense against pathogens. 3. Identify the proteins found on the surface of pathogens. 4. Identify the proteins produced to help fight the pathogen. 5. Identify the 2 types of immunity. 6. How can you get passive immunity? 7. How can you get active immunity? 8. Identify the contents of a vaccine? A B C Which substances may form in the human body due to invaders entering the blood? a. nutrients b. vaccines c. antibodies d. red blood cells Which phrase does not describe a way the human body responds to fight disease? a. destruction of infectious agents by white blood cells b. production of antibodies by white blood cells c. increased production of white blood cells d. production of pathogens by white blood cells Which statement does not identify a characteristic of antibodies? a. They are produced by the body in response to the presence of foreign substances. b. They may be produced in response to an antigen. c. They are nonspecific, acting against any foreign substance in the body. d. They may be produced by white blood cells. Which statement best describes an immune response? a. It always produces antibiotics. b. It usually involves the recognition and destruction of pathogens. c. It stimulates asexual reproduction and resistance in pathogens. d. It releases red blood cells that destroy parasites. Part of the body’s first line of defense against disease-causing organisms is a. the immune system b. the skin c. antibodies d. interferon Molecules that are foreign to your body are called a. antibodies b. white blood cells c. antigens d. histamines A(n) __ is a substance made by an organism in response to invading substances and disease-causing organisms. a. allergen b. antibody c. antigen d. pathogen The immune system of humans may respond to chemicals on the surface of an invading organism. 1. What are these chemicals on the surface called? 2. Explain what will happen once these chemicals enter the body. Which statement best describes an immune response? a. It always produces antibiotics. b. It usually involves the recognition and destruction of pathogens. c. It stimulates asexual reproduction and resistance in pathogens. d. It releases red blood cells that destroy parasites. Molecules that are foreign to your body are called a. antibodies b. white blood cells c. antigens d. histamines A(n) __ is a substance made by an organism in response to invading substances and disease-causing organisms. a. allergen b. antibody c. antigen d. pathogen Resistance to a specific disease is a(n) a. antibiotic. b. immunity. c. white blood cells. d. addiction Once you have had the chicken pox, it is unlikely that you will ever get the disease again because your body has developed a(n) a. passive immunity. b. addiction. c. active immunity. d. antibiotic. Immunity that occurs when a body makes its own antibodies is called _________immunity. a. Passive b. Temporary c. Shortened d. Active An injection of a weakened virus that allows one to develop immunity against a disease is called a a. antibody b. vaccine c. epidemic d. pathogen Which of the following parts of the body's defense system seeks out and destroys bacteria? a. mucus b. white blood cells c. skin d. red blood cells B C A Identify each labeled structure and support your answer.