FASCIOLA hepatica
Disease:
Fascioliasis & liver rot in animals.
Distribution:
- Common in cattle & sheep raising countries.
FASCIOLA hepatica
 Definitive host : man
 Reservoir host: Cattle, sheep ,goats, buffaloes
 Habitat: Bile ducts.
 Intermediate host: Lymnaea snails.
 Infective stage : Encysted metacercaria.
Mode of infection
Ingestion of raw vegitation or
water containing encysted
metacercaria.
Life cycle:
Adult FASCIOLA Hepatica
Egg:
•Size : 140 X 70 µm.
•Shape: Oval, Thin walled with operculum.
• Color : Yellowish brown (bile stained).
•Contents : Ovum & yolk cells (immature).
Miracidium
•Pyriform.
•Ciliated.
Lymnaea snails
Cercaria (Leptocercus)
 Last larval stage inside the snail.
 No sexual organs.
 Cystogenous glands (help in
passing out of snail & in encysting
on vegetations or water).
 Tail: simple & helps in leaving the
snail.
Encysted Metacercaria
 Without tail.
 Surrounded by a cyst
wall.
Clinical Picture :
 Fever.
 Pain & tenderness in right hypochondrium.
 Biliary colics.
 Hepatomegaly,
 Jaundice.
 Vomiting & diarrhoea.
 Toxaemia.
 Anaemia & eosinophilia.
Diagnosis
I.
Clinically : A highly suggestive tetrad of:
 Fever.
 Hepatomegaly.


Pain & tenderness in the right
hypochondrium.
Eosinophilia.
Diagnosis
II- Laboratory :
a. Direct methods
1. Stool examination by direct smear & concentration
methods to find the characteristic eggs.
2. Bile aspiration from the duodenum & examine for
eggs.
3. US.
4. Computerized tomography (C.T).
Diagnosis
Diagnosis
b. Indirect Methods
 ELISA, IHA ,CIEP
 Eosinophilia.
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