Processing Food and Nutrition Chapter 46 Learning Objective 1 • Describe food processing, including ingestion, digestion, absorption, and egestion or elimination • Compare the digestive system of a cnidarian (such as Hydra) with that of an earthworm or vertebrate Nutrition • The process of taking in and using food Food Processing • Feeding • • Digestion • • breaking down food mechanically, chemically Absorption • • selection, acquisition, and ingestion of food nutrients pass from digestive tract into blood Egestion (elimination) • undigested, unabsorbed food discharged Cnidarians and Flatworms • Food digested in gastrovascular cavity • • only one opening serves as both mouth and anus Gastrovascular Cavities Wastes Food Tentacle Mouth Food Enzymes secreted by inner layer Gastrovascular cavity (b) Exhalation. Food absorbed Gastrodermis (a) Hydra Fig. 46-2a, p. 992 (b) Flatworm Gastrovascular cavity Epidermis Food particles Pharynx Mouth Food absorbed Enzymes Wastes Lining of the intestine Food Fig. 46-2b, p. 992 Complex Invertebrates and Vertebrates • Digestive tract is complete tube • • As food passes through tube • • with opening at each end digestion takes place Parts of digestive tract are specialized • to perform specific functions Complete Digestive Tract Crop Gizzard Esophagus Intestine Pharynx Mouth Anus Wastes Food Fig. 46-3, p. 992 Explore various digestive systems by clicking on the figure in ThomsonNOW. KEY CONCEPTS • Food processing includes ingestion, digestion, absorption, and elimination Adaptations for Obtaining Food KEY CONCEPTS • Many animal adaptations are associated with mode of nutrition Learning Objective 2 • Trace the pathway traveled by an ingested meal in the human digestive system • Describe the structure and function of each organ involved Human Digestive System 1 • Mouth • • Mechanical, enzymatic digestion of carbohydrates Mammalian teeth • • • incisors for biting canines for tearing food premolars, molars for crushing and grinding Teeth and Diet Incisors Canines Premolars Molars (a) Carnivore. Fig. 46-6a, p. 994 Canine Incisors Premolars Molars (b) Herbivore. Fig. 46-6b, p. 994 Canines Incisors Premolars Molars (c) Omnivore. Fig. 46-6c, p. 994 Tooth Structure Crown Enamel Gum Pulp cavity Neck Pulp Dentin Cementum Root canal Root Spongy bone Nerve Vein (a) Human lower molar. Sagittal section showing the crown, neck, and root. Artery (b) X-ray of a healthy tooth. Fig. 46-7, p. 995 Human Digestive System 2 • Three pairs of salivary glands • • secrete saliva (enzyme salivary amylase digests starch) Pharynx and esophagus • carry food to stomach Human Digestive System 3 • Peristalsis • • • waves of muscular contraction pushes bolus of food along digestive tract Stomach • • mechanical digestion by vigorous churning enzyme pepsin in gastric juice digests proteins Peristalsis Esophagus Circular muscles contract, constricting passageway and pushing bolus ahead Food bolus Relaxed muscle layer Longitudinal muscles contract, shortening passageway ahead of the bolus Sphincter closed A bolus is moved through the esophagus by peristaltic contractions. Stomach Relaxed muscle layer Sphincter open Stomach When the sphincter (ring of muscle) at the entrance of the stomach opens, food enters the stomach. Fig. 46-8, p. 995 Human Digestive System 4 • Rugae • • • folds in stomach wall expand as stomach fills with food Gastric glands secrete • • hydrochloric acid pepsinogen (precursor of pepsin) Stomach Structure Visceral peritoneum Esophagus Sphincter Circular muscle layer Longitudinal muscle layer Oblique muscle layer Pyloric sphincter Duodenum Rugae Fig. 46-9a, p. 996 Openings into gastric glands Gastric glands Epithelium Lymph nodule Gastric mucosa Fig. 46-9b (1), p. 996 Chief cell Parietal cell Nuclei Surface epithelium Chief cells Parietal cells Gastric glands Gastric glands Fig. 46-9b (2), p. 996 Human Digestive System 5 • Chyme • • • • soup of partly digested food leaves stomach through pylorus enters small intestine in spurts Duodenum • • • location of most enzymatic digestion produces several digestive enzymes receives secretions from liver and pancreas Structure of Digestive Tract VISCERAL PERITONEUM Lymph nodule Villi Blood vessels SUBMUCOSA Nerve fibers MUCOSA MUSCLE LAYER Inner circular fibers Outer longitudinal fibers Fig. 46-5, p. 993 Human Digestive System 6 • Liver produces bile • • Pancreas releases enzymes • • which emulsifies fats digest protein, lipid, carbohydrate, RNA, DNA Trypsin and chymotrypsin • digest polypeptides to dipeptides Human Digestive System 7 • Pancreatic lipase • • degrades fats Pancreatic amylase • digests complex carbohydrates Liver and Pancreas Stomach Inferior vena cava Right lobe of liver Right hepatic duct Common bile duct Pancreas Hepatic portal vein Pancreatic duct Gallbladder Duodenum Fig. 46-11, p. 998 Human Digestive System 8 • Large intestine • • • cecum, colon, rectum, anus eliminates undigested wastes incubates bacteria (produce vitamin K, certain B vitamins) Human Digestive System Parotid salivary gland Pharynx Esophagus Liver Gallbladder Ascending colon lleum Sublingual salivary gland Submandibular salivary gland Stomach Duodenum Pancreas Transverse colon Jejunum Descending colon Cecum Vermiform appendix Sigmoid colon Rectum Anus Fig. 46-4, p. 993 Insert “Human digestive system” human_digestive_m.swf Learn more about human digestion by clicking on the figures in ThomsonNOW. KEY CONCEPTS • Various parts of the vertebrate digestive system are specialized to perform specific functions; accessory glands (liver, pancreas, and salivary glands) secrete fluids and enzymes important in digestion Learning Objective 3 • Describe the step-by-step digestion of carbohydrate, protein, and lipid Carbohydrate Digestion • Polysaccharides • • digested to disaccharide maltose by salivary and pancreatic amylases Maltase in small intestine • splits maltose into glucose (main product of carbohydrate digestion) Protein Digestion • Proteins are split • • • by pepsin in stomach by proteolytic enzymes in pancreatic juice Dipeptidases • split small peptides into amino acids Lipid Digestion • Lipids are emulsified by bile salts • then hydrolyzed by pancreatic lipase Learning Objective 4 • What structural adaptations increase the surface area of the digestive tract? Surface Area of the Small Intestine • Greatly expanded by • • • folds in wall (rugae) intestinal villi (projections of mucosa) microvilli (plasma membrane projections of epithelial cells of villi) Villi and Microvilli Fig. 46-10a, p. 997 Villi Epithelial cells lining villus Capillary network Nerve fiber Mucosa Openings of intestinal glands Goblet cells Intestinal glands Submucosa Lacteal Lymph vessel Muscle layer Visceral peritoneum (b) Fig. 46-10b, p. 997 Fig. 46-10c, p. 997 Learning Objective 5 • Compare lipid absorption with absorption of other nutrients Nutrient Absorption • Nutrients are absorbed through thin walls of intestinal villi • Hepatic portal vein transports amino acids and glucose to liver Lipid Absorption 1 • Fatty acids and monoacylglycerols • • • enter epithelial cells in intestinal lining are reassembled into triacylglycerols then packaged into chylomicron droplets Lipid Absorption 2 • Chylomicrons • • • also contain cholesterol and phospholipids are covered by a protein coat Lymphatic system • transports chylomicrons to blood circulation Learning Objective 6 • Summarize the nutritional requirements for dietary carbohydrates, lipids, and proteins • Trace the fate of glucose, lipids, and amino acids after their absorption A Balanced Diet • Humans and other animals require • • • • • carbohydrates lipids proteins vitamins minerals Carbohydrates 1 • Most are ingested as polysaccharides • starch and cellulose • Polysaccharides are complex carbohydrates • Fiber • mixture of cellulose, other indigestible carbohydrates Carbohydrates 2 • Carbohydrates • • Glucose concentration in blood • • used mainly as energy source is carefully regulated Excess glucose • • is stored as glycogen or converted to fat Lipids 1 • Used to • • • • provide energy form components of cell membranes synthesize steroid hormones, other lipid substances Most lipids are ingested as triacylglycerols Lipids 2 • Fatty acids are converted to molecules of acetyl coenzyme A • • which enter citric acid cycle Excess fatty acids • • are converted to triacylglycerol stored as fat Lipids 3 • Lipids are transported as large molecular complexes (lipoproteins) • Low-density lipoproteins (LDLs) • • deliver cholesterol to cells High-density lipoproteins (HDLs) • • collect excess cholesterol transport it to liver Fat Metabolism Fat cell Fat Fatty acids + Glycerol Transported in blood Liver + Glycerol Fatty acid Used to Acetyl CoA make triacylglycerols Ketone bodies G3P Enters cellular respiration Glucose Converted to other lipids Enters cellular respiration Pyruvate or acetyl CoA Other cells Enters Converted cellular to other respiration lipids Fig. 46-13, p. 1002 Fat cell Fat Fatty acids + Glycerol Transported in blood Liver + Fatty acid Used to Acetyl CoA make triacylglycerols Ketone bodies Glycerol G3P Enters cellular respiration Glucose Converted to other lipids Enters cellular respiration Pyruvate or acetyl CoA Other cells Enters cellular Converted to other respiration lipids Stepped Art Fig. 46-13, p. 1002 Proteins 1 • Proteins serve as enzymes • • Best distribution of essential amino acids • • and essential structural components of cells in complete proteins of animal foods Excess amino acids • are deaminated by liver cells Proteins 2 • Amino groups are converted to urea • • excreted in urine Remaining keto acids are • • converted to carbohydrate and used as fuel converted to lipid and stored in fat cells Protein Metabolism AMINO ACIDS Catabolism Anabolism Excess amino acids Deamination Structural proteins, hemoglobin, myosin, actin, enzymes, plasma proteins NH3 (ammonia) + -keto acids Liver Urea Fat Pyruvate, ketoglutarate Acetyl CoA Enters cellular respiration Ketone bodies To kidneys Acetyl CoA Fatty acids + glycerol Triacylglycerol Storage in fat cells Fig. 46-14, p. 1003 Learning Objective 7 • Describe the nutritional functions of vitamins, minerals, and phytochemicals Vitamins • Organic compounds required in small amounts for biochemical processes • • Fat-soluble vitamins • • components of coenzymes vitamins A, D, E, K Water-soluble vitamins • B and C vitamins Minerals • Inorganic nutrients ingested as salts • • dissolved in food and water Trace elements • • minerals required in small amounts (< 100 mg/day) Phytochemicals • Plant compounds that promote health • • many are antioxidants that destroy oxidants Oxidants • • free radicals, other reactive molecules damage DNA, proteins, unsaturated fatty acids by snatching electrons KEY CONCEPTS • Most animals require the same basic nutrients: carbohydrates, lipids, proteins, vitamins, and minerals Learning Objective 8 • Contrast basal metabolic rate with total metabolic rate • Write the basic energy equation for maintaining body weight, and describe the consequences of altering it in either direction Measuring Metabolism • Basal metabolic rate (BMR) • • body’s cost of metabolic living Total metabolic rate • BMR plus energy used to carry on daily activities Energy • If energy (kcal) input equals energy output • • If energy output exceeds energy input • • body weight remains constant body weight decreases If energy input exceeds energy output • body weight increases Learning Objective 9 • In general terms, describe the effects of malnutrition, including both undernutrition and overnutrition Undernutrition • Form of malnutrition • • • causes fatigue depresses immune function Essential amino acids • nutrients most often deficient in diet Protein Deficiency Overnutrition • Obesity • • • • serious form of malnutrition excess fat accumulates in adipose tissues factor in heart disease, diabetes mellitus, other disorders Person gains weight taking in more energy (kilocalories) than expended in activity KEY CONCEPTS • • Basal metabolic rate is the body’s cost of metabolic living When energy (kilocalories) input equals energy output, body weight remains constant Learning Objective 10 • Summarize current hypotheses about the regulation of food intake and energy homeostasis, including the roles of leptin and neuropeptide Y Leptin • Hormone produced by fat cells • • in proportion to body fat Signals brain about status of energy stores Effect of Leptin Neuropeptide Y (NPY) • Neurotransmitter produced in hypothalamus • • increases appetite Slows metabolism when leptin levels and food intake are low Insert “Chronology of leptin research” leptin_research.swf Learn more about leptins and body weight by clicking on the figure in ThomsonNOW.