Gastroenteritis Inflammation of Stomach and intestines resulting in diarrhea, vomiting and abdominal cramps. History: Contracting the infectious agent 12 to 72 hours before the complain. Symptoms and signs: 1- Diarrhea. 2- Vomiting. 3- Abdominal cramps. 4- Fever. 5- Fatigue. 6- Headache. 7- Muscle pain. 8- Bloody stool. 9- Dehydration. 10 – Poor skin elasticity. 11 – Arthritis. Causative organisms: A – Viruses: 1 – Rotavirus. 1 2 – Norovirus. 3 – Adenovirus. 4 – Astrovirus. B – Bacteria: 1 – Campylobacter jejuni. 2 - Salmonella. 3 – Shigella. 4 – Escherichia coli. 5 – Clostridium dificile. 6 – Vibrio cholera. 7 – Vibrio el-tor. C – Protozoa: 1 – Giardia lambia. 2 – Entamoeba histolytica. 3 – Cryptosporidium. Transmission: 1 – Cntaminated water with sewage. 2 – Contaminated cooked food( from food handlers). 3 – Uncooked food: a – Vegetables fertilized with human excreta. 2 b – Poultry and eggs( Salmonella enteritidis). c – Fish and snails. d – Water or food contaminated with rat excreta. e - Water or food contaminated with different animal excreta ( Giardia). f – Mechanical transmission by insects or animals. Diagnosis: 1- Mainly through symptoms and signs. 2- Stool culture in bloody diarrhea. Differential diagnosis: 1 – Appendicitis. 2 – Volvulus. 3 – Irritable bowel syndrome. 4 – Urinary tract infection. 5 – Abuse of drugs or herbes( induce laxation). Prevention: 1 – Supply with fresh clean water. 2 – Good hygiene. 3 – Hand washing. 4 – Breast feeding. 5 – Food freezing( Meat, fish, etc). 3 6 – Avoid contaminated food or drink. 7 – Vaccination with rotavirus vaccine. 8 - Vaccination with cholera vaccine( 60 % effectiveness). Management: 1 – Many cases are acute self limited diseases does not require medication. 2 – Oral rehydration with all kinds of fluids and the best is fresh fruits juice to correct electrolyte imbalance. 3 – Intravenous rehydration( infants and cholera). 4 – Natural antipyretics( fever): bathing is much better than putting cold dressing on head and extremities. 5 – Medical antipyretic as acetyl salicylic acid. 5 – Diet must not be stooped. Cooked rice and vegetable soap are recommended. 6 – Probiotics ( lactobacillus acidophilus sps.) to colonized in the intestines. 7 – Antiemetics (suprarenal gland product). 8 – Antibiotics: a – Sulfa Guanidine. b – Streptomycin. c – Vancomycin. d – Azithromycin. e – Macroloide. 4 f – Fluoroquinolones. 9 – Mitronidazole to treat Entameba and anaerobic infections. 10 – Antimotility agents: cause complications and we advice to not use. Case no 1: A child 2 years old with Coma, Pallor , unrefrectable and feverish. his mother told us that he have diarrhea and vomiting since 2 days. when we examine we found that the temperature is 40.2 °C and the skin is unelastic, the eyes were depressed and the tongue was dried. A- What are the investigations you need to diagnose the case? B- What is the diagnosis? C- What is the differential diagnosis? D- What is the causes? E- What is the plan for management? F- What is the treatment in details? G- What is the mistakes may be done by the medical staff can lead to delayed healing? 5 Case no 2: A man 50 years complain from diarrhea,abdominal cramp and odourless flatus. when we asked him we find that he is working a teacher, have work trouble, married and family is out country. when we examine we found that he have the signs of depression and his abdomen is distended. A- What are the investigations you need to diagnose the case? B- What is the diagnosis? C- What is the differential diagnosis? D- What is the causes? E- What is the plan for management? F- What is the treatment in details? G- What is the mistakes may be done by the medical staff can lead to delayed healing? 6 Case no. 3: A university student 22 yearscomplain from diarrhea 10 times/day. When we asked told us that he is from damam, living alone at Zulfi and eat his 3 meals in the cheap restaurants at the town. when examined we find the blood pressure 130/80, pulse 75/min ,systolic murmur, pallor and temperature 39°C. A- What are the investigations you need to diagnose the case? B- What is the diagnosis? C- What is the differential diagnosis? D- What is the causes? E- What is the plan for management? F- What is the treatment in details? G- What is the mistakes may be done by the medical staff can lead to delayed healing? 7