Site Surveillance Using Differential Detection

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IBM T. J. Watson Research Center

Site Surveillance Using Differential Detection

Murray Campbell

© 2004 IBM Corporation

IBM T. J. Watson Research Center

Acknowledgements

 Based on work of Vijay Iyengar, Ed Pednault

 This material is based upon work supported by the Air Force Research Laboratory(AFRL)/Defense

Advanced Research Projects Agency (DARPA) under AFRL Contract No. F30602-01-C-0184. Any opinions, findings, conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the AFRL and/or DARPA. Approved for Public

Release, Distribution Unlimited (5/3/2004).

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Site-Based Bio-Surveillance

The monitoring of a geographically constrained site with a relatively stable population for signs of disease outbreak.

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 Example of sites could include work sites, university campuses, or military bases

 The population need not be present 24 hours a day

Site Surveillance Using Differential Detection 2004-02-19 © 2004 IBM Corporation

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IBM T. J. Watson Research Center

What makes “Site-Based” Bio-Surveillance Different?

 Increased data availability

– Central authority for permissions

– Centralized data collection

 “Permissive”

– “Sensitive” data more likely to be available

 Relatively stable population

– May be more homogenous than general population

 Geographically constrained

– Spatial considerations are greatly reduced or eliminated

Site Surveillance Using Differential Detection 2004-02-19 © 2004 IBM Corporation

IBM T. J. Watson Research Center

Differential Detection Approach

 Define sites (regions) that normally track each other

– Determine appropriate model for measured quantities

• Quantify normal variation in the tracking

 Detect significant deviations in the tracking

– Signifies event affecting one of the sites

5 Site Surveillance Using Differential Detection 2004-02-19 © 2004 IBM Corporation

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Differential Detection Approach

Reference Site

Reference Site

Target Site

Reference Site

Reference Site

Reference Site

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IBM T. J. Watson Research Center

Experiments

 Monitor phone calling patterns at two IBM sites

– Yorktown, Hawthorne (10 miles apart)

Counts of calls/callers to medical facilities

– Counts of all calls/callers

Currently being collected on a daily basis

– Privacy ensured through

• Anonymization of calling number

• No reporting of called number

© 2004 IBM Corporation 7 Site Surveillance Using Differential Detection 2004-02-19

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Method

 Assume underlying Poisson process

 Define two time windows

– History, Test

 Model ratio of counts in a window

 Use Chi-squared statistic to detect deviations

– Empirical variance estimate

2   i

T

( t i

 

 r i

)

2

© 2004 IBM Corporation Site Surveillance Using Differential Detection 2004-02-19

IBM T. J. Watson Research Center

Medically-Related Calls

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IBM T. J. Watson Research Center

All Calls

10 Site Surveillance Using Differential Detection 2004-02-19 © 2004 IBM Corporation

IBM T. J. Watson Research Center

Issues

 Requires

– Good tracking

Significant volumes

 Can use

– Raw counts

– Counts adjusted by domain knowledge

• If sites respond differently to some phenomenon

11 Site Surveillance Using Differential Detection 2004-02-19 © 2004 IBM Corporation

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