TTR-52 clusters around apoptotic cells, because
A) It is a membrane protein
B) It is a bridging molecule that binds PS
C) It is made in apoptotic cells
D) It is a receptor for PS
E) None of above
Which of the following is important for
TTR-52 activity
A.
B.
C.
D.
E.
The signal sequence
The transthyretin-like domain
Its ability to bind PS
Its ability to bind CED-1
All of the above
TTR-52 was found to act in the ced-1
pathway, because
A. It can bind CED-1
B. Inactivation of ttr-52 does not enhance the
engulfment defect of the ced-1 mutant
C. It is a bridging protein that binds PS
D. It co-localizes with CED-1 to apoptotic cells
E. None of the above
In Figure 7, ttr-52(lf) can block the missing cell
phenotype caused by loss of tat-1, because
A. ttr-52 is required to recognize living cells with
surface-exposed PS
B. ttr-52 is required to externalize PS in the
missing cells
C. ttr-52 is required to recognize a new “eatme” signal on the living cells
D. ttr-52 can kill these cells directly
E. None of the above