Maui Community College Course Outline 1. Course Title BIOCH 244 Essentials of Biochemistry Number of credits Three (3) Abbreviated Course Title ESSEN OF BIOCHEM Date of Outline 2. Course Description 3. Credits/ Contact Hours June 26, 2001 Introduces chemical principles and concepts of living systems. Emphasizes the composition, function, and transformation of biological substances in animals, plants, and microorganisms. Provides sufficient organic chemistry to supplement a thorough understanding of the general concepts of biochemistry Lecture- Three (3)/week Prerequisites BIOCH 241, or CHEM I51, or CHEM 161, or consent Corequisites NA Recommended Preparation NA Approved by _____________________________Date_________________ 2 5. General Course Objectives To utilize an understanding of the concepts, theories, and applications of general, inorganic, and organic chemistry, in developing an understanding of the concepts and principles of biochemistry and the chemistry of living systems. 6. Specific Course Competencies a. Be able to draw pictures of and name the common organic functional groups. b. Be able to draw structural diagrams and condensed formulas for the major types of organic compounds. c. Name molecules using IUPAC system from the 16 major classes of compounds having been shown the condensed formula. d. Draw all structural isomers of a molecule having been shown its formula. e. Distinguish between structural, geometric, and optical isomers. f. Distinguish between the physical and chemical properties of the 16 important types of organic compounds. g. Draw the products of a chemical reaction given the reacting organic molecules and the chemical reagents. h. Distinguish the 4 major groups of biological molecules and understand their roles in living systems. i. Explain the process of DNA replication and the role of DNA in cellular metabolic regulation and reproduction. j. Describe the process of Protein Synthesis and its application to gene expression. k. Explain the organization and role of enzymes in cellular metabolism. l. Describe the Process of energy transfer and kinetics in biological systems m. Describe and reproduce the chemical pathways in the production and breakdown of Lipids, Carbohydrates, Proteins, Amino acids, and Nucleic Acids. n. State the role of diet and nutrition in the assimilation and utilization of the major biological macromolecules and other nutrients.. o. Discuss the role of biochemistry in modern medicine. 3 7. Recommended Course Content and Approximate Time Spent 2-4 Weeks Review of Organic Chemistry. 1 Week Lipids 2 Weeks Amino Acids and Proteins 2 Weeks Nucleic Acids 1-2 Weeks Enzymes 1-2 Weeks Biochemical Energy transfer 1 Week Carbohydrate Metabolism 1 Week Lipid Metabolism 1 Week Protein Metabolism 1-2 Weeks Nutrition 1-2Weeks Current topics in Biochemistry 8. Recommended Course Requirements Specific course requirements are at the discretion of the instructor at the time the course is being offered. Suggested requirements might include, but are not limited to: Written or oral examinations Homework assignments Quizzes Projects or research (written reports and/or oral class presentations) Attendance and/or class participation 4 9. Text and Materials An appropriate text(s) and materials will be chosen at the time the course is to be offered from those currently available in the field. Examples include Texts: Kroschwitz and Winokur, Chemistry: General, Organic, Biological. 2nd edition, McGraw- Hill Blei and Odian, General Organic and Biochemistry 1st edition, W. H. Freeman and Company Text may be supplemented with: Journal articles Website articles Newspaper, textbook, and periodical references Other: Appropriate films, videos, or internet sites, Television programs Guest speakers Other instructional aids 10. Evaluation and Grading Examinations Quizzes Reports/Assignments Attendance/Participation 60 – 80% 10 - 20% 5 - 20% 5 - 10% 11. Methods of Instruction Instructional Methods vary considerably with instructors and specific instructional methods will be at the discretion of the instructor teaching the course. Suggested techniques might include, but are not limited to: Lecture. Problem solving, and class exercises and reading. Class discussions or guest lecturers. Audio, visual, or presentations involving the internet. Student class presentations. Group or individual projects.