1) mutations • A) occur randomly with respect to fitness effects, but non-randomly in a biochemical sense • B) occur very rarely on a perorganism/generation basis • C) can produce new alleles of existing genes, but not new genes • D) usually increase organism fitness • E) all of the above 2) Chromosome inversions • A) are not a type of mutation because the DNA sequence is unchanged • B) typically occur in bacteria and archea, but not eukarya • C) are selectively neutral, and evolve in a clocklike manner • D) prevent recombination among alleles of genes within the inversion • E) facilitate recombination among alleles of genes within the inversion 3) Genetic variation in wild populations is • • • • • A) often measured as heterozygosity B) often rather low C) often due to synonymous substitutions D) all of the above E) just A and C above 4) A population of 50 diploid individuals has 20 that are Aa, 20 that are AA, and 10 that are aa. What is the allele frequency of the a allele? • • • • • A) 80% B) 60% C) 40% D) 20% E) 50% 5) The most common means of gene duplication is • • • • • A) a frame-shift B) a knockout mutation C) unequal crossover D) polyploidy E) inversion 6) Gene duplication is evolutionarily important because • A) it increases genome size, and larger genomes are more advanced • B) it allows different versions of a gene to specialize in slightly different functions • C) it shows genetic homology among related groups of organisms • D) it facilitates adaptation to different conditions at different life stages • E) all of the above except A