REPRODUCTIVE SYSTEM Power Point Notes MALE REPRODUCTION... What do I need to know? # Learning Outcomes Text Pages P1 Identify and give functions for each of the following: testes (seminiferous tubules and interstitial cells), epididymis, ductus (vas) deferens, prostate gland, cowper's gland, seminal vesicles, penis. P. 416-417 P2 Demonstrate a knowledge of the path of sperm from the seminiferous tubules to the urethral opening. P. 414-415 P3 List the functions of seminal fluid. P. 414-415 P4 Identify the tail, midpiece, head, and acrosome of a mature sperm and state their functions. P. 416-417 P5 Describe the functions of testosterone. P. 417 P6 Demonstrate knowledge of the control of testosterone levels the endocrine system. P. 417 VOCABULARY _____ Birth canal _____ Buffer _____ Bulbourethral gland _____ Cervix _____ Clitoris _____ Copulation _____ Corpus luteum _____ Cowper’s glands _____ Ductus (vas) deferens _____ Ejaculation _____ Endometrium _____ Epididymus _____ Erectile tissue _____ Estrogen _____ External genitalia _____ Fimbria _____ Follicles _____ Follicular phase _____ FSH ____ GnRH ____ Gonads _____ HCG _____ Implantation _____ Interstitial cells _____ Labia _____ Leutenizing hormone _____ Luteal phase _____ Menopause _____ Menstrual phase _____ Menstruation (menses) _____ Oogenesis _____ Ova _____ Ovaries _____ Oviduct _____ Ovarian cycle _____ Ovulation _____ Oxytocin _____ Pap smear _____ Penis _____ Placenta _____ Pregnancy _____ Progesterone _____ Proliferative phase _____ Prostate gland _____ Puberty _____ Scrotum _____ Secretory phase _____ Semen _____ Seminal fluid _____ Seminal vesicles _____ Seminiferous tubules _____ Spermatogenesis _____ Spermatogonia _____ Spermatozoa (sperm) _____ Testes _____ Testosterone _____ Urethra _____ Uterine cycle _____ Uterus _____ Vagina _____ Vulva _____ Womb HUMAN REPRODUCTION: The goal of the reproductive system is to pass on your _____________________ onto a new and unique generation. This is ultimately accomplished via ___________________. LIFE CYCLE: Human reproduction employs ________________________, and depends on the integrated action of hormones, the nervous system, and the reproductive system. _______________are the __________, which produce _______ and ___________. ________________are the ________ ,which produce eggs and 2 hormones ___________ and ________________. MALE REPRODUCTION: Male Anatomy The male external genitalia are the _______ and ________. The scrotum is a fold of skin that encloses the male gonads (testes) The testes are a _________________________surrounded by several layers of connective tissues. These tubes are the _____________________________, where sperm are produced by meiosis. About ____________of tubules are packed into each testis. The _______________________________ are scattered between the seminiferous tubules in the testes. These cells ____________________________. Sperm production cannot occur at normal body temperature. So just ______________, the __________________to hang outside the abdominal cavity in the scrotum, a fold of skin. The temperature in the scrotum is ____________________________. SPERMATOGENESIS This, the _______________ _______________________, is a continuous and __________ process in the adult male. Spermatogenesis occurs in the ____________________ of the testes. The spermatogonia undergo repeated _____________ to produce large numbers of potential sperm (spermatocytes) ~_____ million/day. Next, _____________ occurs to create ________________ _______________. The _____________ transfer _____________ to the spermatids, and the developing sperm are gradually ________________ ________________ of the seminiferous tubule and make their way to the _____________. When the spermatids reach the epidymis, they _________ _____________, and are ________________. The process from ____________________________ ____________________, takes ____________ in the human male. ___________________of a human male contains about ________ ______________________ Sperm production begins at ___________ and continues throughout life, with several hundred million sperm being produced each day. SPERM CELLS The structure of a sperm cell fits its function. The thick __________ contains the ______ ___________ and is tipped with a special body, the ____________. The acrosome contains ___________ that help the sperm _______________________. The ___________ contains large numbers of ________________ that provide ______ for ________________. The tail is a _____________ which ______ _____________________. During ejaculation, the sperm are propelled from the epididymis through the muscular ___________ ______________ ducts, which run from the scrotum around and behind the bladder, where they join to form a short ________________________. This duct opens into the _________, the tube which drains both the excretory and reproductive systems (never both at the same time). The urethra runs through the penis and opens to the outside at the tip of the penis. SEMEN and ACCESSORY GLANDS: In addition to the testes and ducts, the male reproductive system contains three sets of glands that add their secretions to the ______________ (the fluid ejaculated). 1. __________________: contribute about _____________ __________________. This pair of glands lies below and behind the bladder and empties into the ejaculatory duct. The fluid is _______________and contains ________ _____________________________________ (which provides _______________ for the sperm). These vesicles also secrete ____________________, which once in the female reproductive tract, _______________________ of the uterine muscles that help move the semen up into the uterus. ____________ in the seminal fluid _______________________________ after it is deposited in the female, thus, making it easier for uterine contractions to move the semen. 2. _______________________: This is the _____________ of the accessory glands. Prostatic fluid is ____________ _______________________, which ____________________ of any residual ____________ in the urethra and the natural acidity of the _____________. This gland is the sources of some of the ________________________________________________ _____________________. A benign enlargement of the prostate occurs in ___________________ of all men in this age group. That is why it is important to get tested annually after the age of 40. 3. _______________________________ (cowper’s gland): These are a pair of ___________ along the urethra below the prostate. They secrete a _______________________________________ ____. It has been suggested that this fluid ___________________________, but the volume (just one or two drops) seems insufficient to be very effective for this function. This fluid __________________ ____________ released before ejaculation. This is one factor in the ___________________________________ of birth control. PENIS: The penis is composed of _________________ derived from ____________________________. During sexual _________________, this erectile tissue fills with __________ from the arteries. As it fills, the increasing ______________ __________________ ___________, causing it to _________________. The resulting erection is essential ______________________ into the vagina (rodents, raccoons, walruses, and several other mammals also possess a _____________, a bone that stiffens the penis). The main shaft of the penis is covered by relatively thick skin, whereas the head “(or _______________) has a much __________ ______________ and is consequently more __________________. The human glans is covered by a fold of skin called the __________ (or prepuce). MALE SEX HORMONES: The principal male sex hormones are the _________________, of which, _______________________ is the most important. Androgens are _________________ produced by the ___________ __________ of the testes, and are directly responsible for the ____________________________________________ of the male. Androgens are also potent determinants of _________in mammals. In addition to specific sexual behaviour and __________ (sex drive), androgens increase general _____________________. ______________ sex characteristics: development of the _____ _____________ and other ducts, the ____________ ______________, and ____________________. All babies start as ______. If testosterone is present, they will become male, if not, they will be born female. Sex is determined by ______________, sex is determined. __________ sex characteristics: Features we associate with ________ such as: deepening of the voice, the male distributions of axillary (armpit), facial, and pubic hair, and muscle growth (androgens stimulate protein synthesis). The __________________ makes a hormone called __________ (the_______________________________ ___________). GnRH controls the release of two hormones from the ______________: 1. ______________________________ 2. _______________________________ _____________ stimulates the _____________________ in the seminiferous tubules to secrete _____________. Testosterone has a role in __________________ and developing male secondary _____________________. ___________ acts on the epidymis to help in______________________. _______________ by testosterone controls the actions of GnRH. PLEASE LABEL THE FOLLOWING DIAGRAM! FEMALE REPRODUCTION… What do I need to know? # Learning Outcome Text Pages P7 Identify and give a function for each of the following: ovaries (follicles and corpus luteum), oviducts (fallopian tubes), uterus, cervix, vagina, clitoris. P. 418-419 P8 Describe the functions of estrogen. P. 421-424 P9 Describe the sequence of events in the ovarian and uterine cycles. P. 420-423 P10 Demonstrate knowledge of the control of the ovarian and uterine cycles by hormones. P. 420-423 P11 Demonstrate knowledge of a positive feedback mechanism involving oxytocin. P. 208, 394 P12 Describe the hormonal changes that occur as a result of implantation. Page 424 The female gonads, ____________, are located within the lower abdominal cavity, below most of the digestive system. Each ovary is enclosed in a tough protective capsule and contains many _______________. A ___________ consists of one egg cell surrounded by one or more layers of follicle cells, which ___________________the developing egg cell. All of the ____________ follicles a woman will ever have are formed at _________. Of these, only __________________________________ during the woman’s reproductive years. After ____________, ____(or rarely two or more) _________ ____________________ during _____________________. The cells of the follicle also produce the primary female sex hormones, ____________. When ___________________ occurs, the ______________ _________________ from the follicle (like a small volcano). The remaining ____________________ within the ovary to form a solid mass called the ____________________. The corpus luteum secretes ______________________ (the hormone of pregnancy) and additional estrogen. If the egg is _____________, the ____________________ ________________ and a new follicle matures during the next cycle. The female reproductive system is not completely closed. The egg cell is expelled into the _____________ __________near the opening of the _____________ (or fallopian tube). The ___________________ on the oviduct ____________________ ______, and the __________ on the inner epithelium lining the duct help collect the egg cell by ____________________to draw fluid into the duct. The oviduct is the ___________________________. The ___________ in this duct also convey the egg cell down the duct to the _____________________ (womb). The _____________ is a thick, __________________(shaped like an upside down pear). It is remarkably small; the uterus of a woman who has never been pregnant is about _________long and ________wide at its widest. The unique arrangement of muscles that make up the uterine wall ________________to accommodate a 4 kg (_____ lb) fetus. The inner lining of the uterus, the _________________, is richly supplied with ________________, in which a fertilized egg implants and develops. The narrow neck of the uterus is the ____________, which opens into the ____________. The vagina is a thin-walled chamber that forms the _______ ___________through which the baby is expelled; it is also the __________ for the man’s penis. The vagina is the terminal portion of the female reproductive system, but it is covered by two pairs of skin folds. The female external genitals are collectively known as the _______________. The ______________are the __________of skin just outside the vaginal opening. They are composed of erectile tissue and enlarge during arousal/intercourse. The ______________, a pair of thick, fatty ridges, At the top of these two folds is a small bulb of erectile tissue called the ______________, which is the female equivalent of the glans of the penis. Like that organ, it is one of the most ________________ of stimulation in sexual response. cover and _____________the genital area. The ___________________(breast) is another structure important to mammalian reproduction, although it is not part of the reproductive tract itself. The secretory apparatus consists of a series of __________, small sacs of epithelial tissue that _________ ________. The aveoli drain into a series of _________ that open at the ______. The _________________________prevents the development of both the secretory apparatus and the fat deposits, so the breasts remain __________and the nipple is not connected to the ________. OOGENESIS The ovary contains many ___________ composed of a __________ _____ surrounded by an outer layer of follicle cells. Each egg begins oogenesis as a primary ________. The development of ova (mature, unfertilized eggs) __________________________in three ways. 1. During meiotic divisions of oogenesis, _________________, as only _____ of the four cells will develop into ________, the other 3 are called ______________(which help to _________ the egg). 2. At birth each female carries ____ _________________ it will ever have, though still in an immature state. 3. Oogenesis is ____________. It has long ‘resting’ periods before the process is complete. ______________, a developing egg is released _____________ from puberty until menopause, a total of _______________. THE FEMALE HORMONES: The pattern of hormone secretion controlling female reproduction differs strikingly from the male pattern, mostly due to its cyclical nature. Whereas the male produces sperm continuously, females ovulate only one or a few eggs at one time during each cycle. The control of this cycle is _____________. THE FEMALE HORMONE CYCLES Two different types of cycles occur in the female mammals: 1. The _______________ cycle 2. The _______________ cycle MENSTRUAL CYCLE : This cycle occurs in the uterus. There are 3 phases in this cycle. _______ is the first day of a woman’s ‘_______’ (1st day of ______________) THREE PHASES OF THE MENSTRUAL CYCLE 1. The _________________: Menstrual _______________ usually persists for a few days (day 2-8). 2. The _________________: the ____________________________for a week or two (until _______________). 3. The _________________: usually about 2 weeks long, the endometrium continues to ______________, becomes more _________________and secretes a fluid rich in ___________ to prepare for a __________________. *If an ________________________ in the uterine lining by the end of the secretory phase, a _____________________________________. *If an _______________________ before the end of the secretory phase, the ______________________________________________. THE OVARIAN CYCLE: This cycle occurs in the ovaries. THREE PHASES OF THE OVARIAN CYCLE: 1. This cycle begins with the _________________, during which several ___________________________ and _________________. The maturing follicle develops an internal fluid-filled cavity and grows very large, forming a _____ near the surface of the ovary. 2. The follicular phase ends with _____________ when the follicle and adjacent wall of the ovary __________, ____________________. The egg cell is transported ________________ and is transported into the uterus. 3. The last phase is the _________________. During this phase, the ___________________ that remains in the ovary after ovulation is ________________________________________. The corpus luteum is an endocrine tissue that synthesizes and ______________________________________________________. The next cycle begins with growth of new follicles. These cyclic phases are interrupted only by ___________ and continue until ________________, when reproductive capability ends. THE FEMALE SEX HORMONES Hormones coordinate the menstrual and ovarian cycles in such a way that growth of the follicle and ovulation are ______________ with preparation of the uterine lining for possible implantation of an embryo. 5 hormones participate in both (+) and (-) feedback cycles: 1. ____________________________ (GnRH): secreted by the _____________________ 2. ______________________(FSH): secreted by _________________ 3. ______________________(LH): secreted by __________________ 4. ________________: secreted by ___________________ 5. ________________: secreted by ___________________ FEMALE HORMONE CONTROL: 1. During the follicular phase of the ovarian cycle, the ___________ ___________________. 2. This causes the ______ ______________ to secrete small quantities of _______________. 3. At this time, the _______ in the ovary __________ _________________, but not for LH. The ________________ ___________________. 4. The follicles _________ ______________ as they grow. The amount of estrogen secreted during this time is small. 5. When the [__________] secretion begins to _____, it causes the ___________________ ____________________(__________ feedback). 6. GnRH causes even ________________to be released from the anterior pituitary. 7. This causes the ______ ____________. 8. By now, the follicles have receptors for LH and can respond to this hormonal cue. The ____________ induces _____________ ____________________ ____________________ 9. _______________ occurs on __________, about _____________ _______________. 10. After ovulation, ______ will _________________ ____________________ ____________________. 11. LH will also stimulate the corpus luteum to start secreting ____________ ____________________. 12. The corpus luteum reaches its maximum development about _____ ____________________. At this point there is very ________________________________________ in the blood. (*at the peak, we start to see symptoms of _____.) 13. High levels of these hormones exerts _______ ____________________________________. 14. This causes a severe ____________the amounts of ___________. 15. When [LH] plummets, the _______________ __________________. 16. This causes a sharp ____________________ ____________________ ____________________ 17. Without these hormones, the ________________________________________and day one of the cycle begins again. 18. As these hormones drop off, the ___________________ ____________________________. 19. So the ____________ ____________begins to ____________enough _________ to stimulate ___________________ _________in the ovary. 20. This initiates the follicular phase of the next ovarian cycle. How is the ovarian cycle synchronized with the menstrual cycle? 1. _________________ phase/___________________ phase: Estrogen (which is released by follicles in the follicular phase) is a hormonal signal to the uterus, which stimulates the development of the endometrium (proliferative phase). 2. __________________________: After ovulation, estrogen and progesterone secreted by the corpus luteum stimulate continued development and maintenance of the endometrium (secretory phase) as the body prepares for the possibility of a fertilized egg. 3. A rapid drop in the level of estrogen and progesterone hormones ______________ _______________________ causes __________________ ________________that deprive the endometrium of blood. ____________________________ results in ____________________ and the beginning of a new menstrual cycle. In the meantime, ovarian follicles that will stimulate renewed thickening of the endometrium are just beginning to grow. In addition to their role in coordinating reproductive cycles, _______________________ are also responsible for the _____________ _____________________ of the female: 1. Deposition of ______________________ 2. Increase in _______________________ 3. Affects calcium metabolism 4. Stimulates _______________________ 5. Mediates female __________________ 6. Initiates female ___________________ 7. ___________ 8. _____________________ 9. _________________ (chocolate, cheese, milk…) 10. _________________ (not as much as men) WHAT HAPPENS IF THE EGG IS FERTILIZED? If the egg is fertilized, the resulting embryo will start to release a hormone called _______________________________________________. ___________________to ________________________and this allows the levels of _______________________________________________. Thus, the ________________ layer is __________________________ and is maintained by the high levels of hormones. The levels of HCG are so high, that some is excreted in the ___________, where it can be detected in _____________. Other changes for the mother in the first trimester include: • Increased mucous in the cervix to form a protective plug. • Growth of the placenta • Enlargement of the uterus • Morning sickness • Mood swings • Weight gain of ~1kg • Cessation of ovulation and menstrual cycling • Breasts become large and tender BIRTH CONTROL ____________________________ (birth control pills) usually contain a combination of ___________________ _______________________________. High levels of these hormones ______ _______________________________, and thus ________________________ _______________________________. And this means __________________ and no fertilization possible. This tricks your body into thinking you are _________________.The days that you take a placebo, would be the days you have your period. OTHER OPTIONS? 1. ______________(Norplant) can be implanted under the skin and offer long-term suppression of ovulation. May double the risk of blood clots. 2. There is also an ________________ available, which you receive once every 3 months (it acts similarly to the pill). 3. RU-486, the ‘___________________’, interferes with implantation of the blastula into the uterine wall. Its use as a contraceptive is very controversial. 4. __________________: physical (condom, diaphragm) or chemical (spermacides) means to separate the sperm from the egg. 5. __________________(most effective) include vasectomy and tubal ligation.