SCB 204.1738, 1739 Quiz 4 FORM C Robyn O’Kane, Ph.D. Spring I 2008 Name_________________________________________________________________ 1. Thyroid-stimulating hormone A. increases the rate of thyroid hormone production. B. allows iodine to be pulled into the thyroid follicular cells. C. is released from the hypothalamus. D. All of the above are correct. E. A and B are correct only. 2. When blood calcium concentration starts to decrease, _________________ is released from the ______________ gland. A. parathyroid hormone; parathyroid B. calcitonin; thyroid 3. When this happens (from previous question), which of the following will be a result? A. Decreased calcium absorption in the GI tract. B. Increased osteoclast activity C. Increased calcium excretion at the kidney (in urine). D. All of the above will happen 4. A tumor in the middle layer of the adrenal cortex will result in increase secretion of A. androgens. B. aldosterone. C. norepinephrine/epinephrine D. cortisol. 5. The hypophyseal portal system A. starts at the supraoptic and paraventricular nuclei. B. shuttles hormone-rich blood from the hypothalamus to the anterior pituitary. C. is the collection of axons that travels down the infundibulum. D. results in hormones being released from the posterior pituitary. Use the following information to answer Questions 6-7 below: Normal blood glucose concentration is between 70-120 mg/dL. 6. When blood glucose concentration is 65 mg/dL, A. glucagon will be released. B. insulin will be released. C. glycogenolysis will occur. D. A and C are correct. E. B and C are correct. 7. This result is an example of A. positive feedback. B. negative feedback. 1 8. Leptin A. levels are low in obese people. B. is released from the hypothalamus. C. helps enhance (increase) appetite. D. gets released from adipocytes when lipids are absorbed. 9. Endocrine secretions are released into the _______________ whereas exocrine secretions are released into the ________________. A. external environment; external environment B. bloodstream; bloodstream C. external environment; bloodstream D. bloodstream; external environment 10. Glucocorticoids have all of the following effects EXCEPT A. increased resistance to stress. B. increased rate of gluconeogenesis. C. increased rate of skeletal muscle breakdown. D. increased rate of sodium reabsorption at the kidneys. 11. Choose the answer that puts epinephrine activity in the correct order: I. Phosphorylates an enzyme to stimulate glycogenolysis II. ATP is converted into cAMP by adenylate cyclase III. A G protein is activated IV. A protein kinase is activated V. Binds to a specific receptor A. I, II, III, IV, V B. V, II, III, IV, I C. V, III, II, IV, I D. V, III, II, I, IV 12. All of the following are correct regarding gonadotropin-releasing hormone EXCEPT A. it controls appetite. B. it is released by the hypothalamus. C. it causes follicle stimulating hormone to be released. D. its action is enhanced by the action of leptin. 13. Graves disease A. is diagnosed by increased levels of TRH and/or TSH but decreased levels of T3/T4. B. is a condition caused by hypothyroidism. C. results when there isn’t enough tyrosine in the body. D. is characterized by an increased metabolic rate. 14. Which of the following is correct regarding Addison’s disease, Cushing’s disease, and congenital adrenal hyperplasia? A. They all can be treated with cortisol injections. B. They all have an increased secretion of ACTH. C. They all produce cortisol in increased amounts. D. They all result in a “moonfaced” appearance. 2 Use the following answer choices for the descriptions in Questions 15-18 below: A. Nervous system B. Endocrine system C. Both systems 15. 16. 17. 18. Responsible for long-term activities, like growth Releases hormones into the bloodstream Short-lived responses Molecules released bind to receptors of the target cells 19. Corticotropin-releasing hormone A. has a permissive effect on leptin. B. release is stimulated by adrenocorticotropic hormone. C. leads to an increase in glucose and other energy precursors in the bloodstream. D. is released from the posterior pituitary. Use the following answer choices for the descriptions/names of hormones in Questions 20-26 below: A. Lipid-soluble 20. 21. 22. 23. 24. 25. 26. B. Water-soluble C. Both categories Activate a G protein Nitric oxide Require a second messenger system Easily diffuse across the cell membrane Directly alter gene expression when bound to a receptor Bind to specific receptors Bound to a transport protein for movement through the bloodstream 27. Extra credit: Type I diabetes results from A. too much insulin being produced by the pancreas. B. destruction or inactivity of the beta cells in the pancreas. C. a lack of exocrine activity of the pancreas. D. obesity. E. All of the above are correct. 28. Extra credit: The exocrine secretions of the pancreas include all of the following EXCEPT A. nucleases. B. amylase. C. a basic buffer. D. pepsinogen. E. trypsinogen. 3