Abstract ID: 14844 Title: Imaging and Radiotherapy for SBRT Liver
Stereotactic body radiation therapy (SBRT) is a highly sophisticated delivery of radiation therapy to an
extracranial lesion in 5 or fewer high dose treatments. Modeled after intracranial stereotactic radiosurgery
(SRS), treatment of brain metastases with a single high dose fraction, SBRT allows for potent ablative
doses to be delivered to extracranial lesions with acceptable toxicity in appropriately selected patients. The
application of SBRT is currently under study in multiple sites including tumors of the spine, lung, pancreas,
prostate, and liver.
The liver is a common site for metastatic disease from a wide variety of malignancies. Management is
dependent on the location and extent of both intrahepatic and extrahepatic disease. In select patients with
limited liver involvement SBRT is an efficacious and well tolerated treatment.
This lecture will focus on SBRT treatment of cancers in the liver. We will review the clinical background
of cancers involving the liver that are amenable to SBRT treatment. We will review the technologic
advancements, the treatment techniques, and the ongoing investigations of SBRT to the liver.
Educational objectives:
1. To understand the definition and technical aspects of SBRT
2. To understand the rationale, indications, and logistics of SBRT for the liver
3. To review the clinical outcomes of SBRT of the liver, including efficacy and toxicity
4. To discuss the Mayo Clinic Jacksonville experience with utilizing SBRT for the liver