MADISON PUBLIC SCHOOLS ENRICHED BIOLOGY Authored by: Suzanne Monkemeier, Linda Luparella, and Stanley Pazden Reviewed by: Mr. Lee S. Nittel Director of Curriculum and Instruction Mr. Tom Paterson K12 Supervisor of Science and Technology Approval Date: Fall 2012 Members of the Board of Education: Lisa Ellis, President Patrick Rowe, Vice-President Kevin Blair Thomas Haralampoudis Linda Gilbert James Novotny David Arthur Shade Grahling Superintendent: Dr. Michael Rossi Madison Public Schools 359 Woodland Road, Madison, NJ 07940 www.madisonpublicschools.org I. Overview This course is designed for students to increase understanding of basic scientific knowledge and processes. This is a survey course covering historical development, evolutionary theories, cellular basis of life, reproduction, genetics and ecology of organisms. Through the use of laboratory investigations, class discussions and evaluation, the students are required to analyze data, understand abstract concepts and apply knowledge to solve new problems. II. Rationale There has been an exponential growth in biological knowledge in recent years. This new knowledge has had a profound impact on how we view our world. Major advances in technology, DNA manipulation, cloning, stem cell research, cell biology and genetics have presented humanity with solutions to problems of the past, and have been the source of new challenges. Students need a sound understanding of fundamental biological concepts. This will enable them to make informed decisions regarding their health, the environment and bioethical issues. III. Student Outcomes New Jersey Core Curriculum Standards 5.1 Science Practices: All students will understand that science is both a body of knowledge and an evidencebased, model-building enterprise that continually extends, refines, and revises knowledge. The four Science Practices strands encompass the knowledge and reasoning skills that students must acquire to be proficient in science. 5.3 Life Science: All students will understand that life science principles are powerful conceptual tools for making sense of the complexity, diversity, and interconnectedness of life on Earth. Order in natural systems arises in accordance with rules that govern the physical world, and the order of natural systems can be modeled and predicted through the use of mathematics. 5.4 Earth Systems Science (B,F,G): All students will understand that Earth operates as a set of complex, dynamic, and interconnected systems, and is a part of the all-encompassing system of the universe. Common Core State Standards for Literacy in Science and Technical Subjects (Grades 11-12) 1. Cite specific textual evidence to support analysis of science and technical texts, attending to important distinctions the author makes and to any gaps or inconsistencies in the account. 2. Determine the central ideas or conclusions of a text; summarize complex concepts, processes, or information presented in a text by paraphrasing them in simpler but still accurate terms. 3. Follow precisely a complex multistep procedure when carrying out experiments, taking measurements, or performing technical tasks; analyze the specific results based on explanations in the text. 4. Determine the meaning of symbols, key terms, and other domain-specific words and phrases as they are used in a specific scientific or technical context relevant to grades 11–12 texts and topics. 5. Analyze how the text structures information or ideas into categories or hierarchies, demonstrating understanding of the information or ideas. 6. Analyze the author’s purpose in providing an explanation, describing a procedure, or discussing an experiment in a text, identifying important issues that remain unresolved. 7. Integrate and evaluate multiple sources of information presented in diverse formats and media (e.g., quantitative data, video, multimedia) in order to address a question or solve a problem. 8. Evaluate the hypotheses, data, analysis, and conclusions in a science or technical text, verifying the data when possible and corroborating or challenging conclusions with other sources of information. 9. Synthesize information from a range of sources (e.g., texts, experiments, simulations) into a coherent understanding of a process, phenomenon, or concept, resolving conflicting information when possible. 10. By the end of grade 12, read and comprehend science/technical texts in the grades 11–12 text complexity band independently and proficiently. IV. Essential Questions and Content Introduction to Biology Essential Questions: What is the nature of science? What is the nature of scientific inquiry? How does scientific knowledge affect our lives? Students should be able to: List and describe the steps of the scientific method. State the proper format for a hypothesis. Explain how quantitative and qualitative data differ from each other. State the differences between the following terms: independent variable, dependent variable, experimental and control. Demonstrate proper use of various microscopes. Identify and state the functions of the parts of a light microscope. Calculate total magnification of an image when objective and ocular lens magnification are given. Measure the diameter of the field of view of a microscope and use magnification information to approximate actual size of image. State how the field of view, magnification, brightness and resolution of a light microscope changes when going from low to high power objective. Explain the differences between light microscopes, scanning electron microscope and transmission electron microscope with respect to sourceof image, magnification, preparation of specimen, type of image and ease of use. Define biology and explain the characteristics of life. Explain what is meant by the term bioethics and give examples. Know and apply proper safety procedures. Utilize scientific equipment properly. Chemistry of Life Essential Questions: What is the chemical basis of living organisms? How are atoms arranged into molecules and cells? Students should be able to: Describe the structure of an atom with respect to the following subatomic particles: proton, electron and neutron. Interpret the Periodic Table. Explain the differences between molecules and ions. Define the isotope and give common examples. State how chemical formulas differ from structural formulas. Explain how covalent and ionic bonds are formed and how they differ using valence electrons. Explain how hydrogen bonding occurs between molecules and the relevance of the electronegativity fluorine, oxygen and nitrogen. Explain how ions are related to the pH scale. Explain how the pH scale relates to acidity and alkalinity of solutions. Identify the components of a reaction. Explain dehydration synthesis and hydrolysis. Explain endergonic and exergonic chemical reactions with respect to absorbing and releasing free energy. Describe the major properties of water. Explain why water is an important biological solvent. Explain the importance of carbon to organisms. List the monomers of carbohydrates, lipids, proteins and nucleic acids. Describe the structure and function of various carbohydrates. List the different categories of lipids. Describe the structure and function of the various categories of lipids. Describe the structure of an amino acid. Explain the four levels of protein structure. State how the following terms are related: catalyst, enzyme, activation energy, active site, substrate and coenzyme. List the basic structure of a nucleotide and state how DNA and RNA differ with respect to the kinds of nucleotides. Explain the differences between DNA and RNA. Cells Essential Questions: What is the basic structural and functional unit of organisms? Are there different types of cells? How do cells function? How are cells organized? Students should be able to: List and describe the contributions of the following scientists: Hooke, Schleiden, Schwann, Van Leeuehenhoek, and Virchow, Explain The Cell Theory. State how the ratio of surface area of cell membrane to cell volume limits the size to which cells can grow. Draw and label the structures found in a typical prokaryotic cell. List and describe the functions of organelles found in typical eukaryotic cells. Explain the differences between prokaryotic cells and eukaryotic cells. Explain the major differences between plant and animal cells. Explain the fluid mosaic model of the cell mcmbrane. Explain the movement of substances into and out of cells. State the differences between active and passive transport and give examples of each form of transport. Describe the following processes: endocytosis, exocytosis, phagocytosis, pinocytosis with regard to cell transport. Photosynthesis and Cellular Respiration Essential Questions: How do organisms acquire the energy needed to sustain life? How is energy transferred from one type of organism to another type? Students should be able to: Describe the basic processes of photosynthesis. Explain why photosynthesis is of vital importance to life on earth. Relate the structure of the chloroplast to its function. State how carbon dioxide and water necessary for photosynthesis reach the chloroplast. Name and explain the role of the pigment molecules involved in photosynthesis. List the major events of the light reactions of photosynthesis. Summarize the Calvin Cycle. Describe the energy transfers that occur during photosynthesis. Differentiate between cyclic and non-cyclic phosphorylation. Discuss the effects of temperature, light intensity, oxygen concentration and carbon dioxide concentration on the rate of photosynthesis. Describe photorespiration and discuss the conditions under which it occurs. Explain how C4 and CAM allow plants to survive under adverse conditions. Distinguish between anaerobic and aerobic respiration. Differentiate between lactic acid fermentation and alcohol fermentation. Name the major stages of aerobic respiration. Describe the major intermediaries and energy carrying molecules generated during each stage of aerobic respiration. Explain the role of oxidation and reduction reactions in cellular respiration. Relate the structure of the mitochondrion to its role in cellular respiration. Summarize the differences in energy output between aerobic and anaerobic respiration. State the role of oxygen in aerobic respiration. Explain the endosymbiont hypothesis and provide evidence to support it. DNA and Protein Synthesis Essential Questions: How does DNA ensure the continuity of life? How is the information encoded in a DNA molecule used to build complex organisms? Students should be able to: Describe the structure of a DNA molecule. Describe the structure of an RNA molecule. List the differences between DNA and RNA molecules. Differentiate between the three types of RNA molecules. Summarize the events of DNA replication. Summarize the process of transcription. Explain how the primary RNA transcript is modified in eukaryotes. Describe translation. Give examples of post translational modifications. Explain how errors in DNA replication are detected and repaired. List the different types of mutations that occur during replication. Describe common techniques that are used in biotechnology. Reproduction, Genetics and Heredity Essential Questions: What processes ensure the continuation of life? How are characteristics inherited? What are the ways to detect hereditary information? Students should be able to: Explain the basic differences in the processes of mitosis and meiosis. Summarize the events of each stage of mitosis and meiosis. Differentiate between spermatogenesis and oogenesis. List the differences which occur between cytokinesis in plants and animals. Explain synapsis, tetrad formation and crossing over. Describe the early developmental stages of sexually reproducing organisms. Explain the basic mechanisms responsible for cellular differentiation and morphogenesis. List and explain Mendel's basic principles. Solve genetic word problems using a Punnett Square. Demonstrate understanding of various modes of inheritance. Employ simple probability to calculate genotypic and phenotypic ratios. Interpret pedigrees and discern patterns of inheritance. Explain what a gene map is and state how one is constructed. Explain how karyotypes are made and tell why they are important in genetic studies. List the various types of mutations that can occur. Explain why amniocentesis, chorionic villus sampling and ultrasound images are important tools in genetic counseling. Provide examples of relatively common human genetic problems and explain their genetic basis. Name common mutagenic agents. Evolution and Natural Selection Essential Questions: How did the chemical basis of life evolve? How do organisms change through time? Students should be able to: State the "Big Bang" theory. Provide a timeline for the formation of the universe. Describe the conditions found on Earth at the time scientists believe life began. Explain Oparin's theory about the origin of life. Distinguish between biogenesis and abiogenesis. Describe the experiments of Redi, Spallanzani and Pasteur. Explain the "Heterotroph Hypothesis". Interpret a phylogenetic tree. Explain the "Endosymbiont hypothesis" and give evidence to support it. Explain the theory of evolution. Distinguish between evolution by means of inheritance of acquired characteristics and evolution by means of Natural Selection. Explain Darwin's Theory of Natural Selection. Describe common misconceptions regarding evolution. Cite evidence which supports the theory of evolution. Explain the theory of punctuated equilibrium. Give examples of how speciation may occur. Trace the phylogeny of modern humans. Discuss alternate theories regarding how life on earth arose. Classification and Taxonomy Essential Questions: Are there evolutionary relationships between organisms? What are the structural and functional adaptations in organisms? How do organisms grow? Students should be able to: Describe the taxonomic system devised by Linnaeus. Write the scientific names of organisms correctly. List the major taxons in the proper hierarchical order. Show an awareness that there are various ways of classifying organisms. Name the five major kingdoms and list the distinguishing characteristic s of each kingdom. Distinguish between archaebacteria and eubacteria. Explain the difference between Gram- positive and Gram -negative bacteria. Describe the process of binary fission. Distinguish between vascular and nonvascular plants. Describe alternation of generations in plants. Describe pollination, seed formation and growth in plants. List and describe the major plant growth regulators. Name the major organs of a plant and describe their functions. Explain major differences between plant and animal cells. List and provide the distinguishing characteristics for the major phyla of animals. Sketch and label organs and organ systems of selected phyla. Compare and contrast the three major life cycles of organisms. Ecology Essential Questions: What is ecology? How do organisms interact with each other? How do organisms interact with their environment? Students should be able to: Define ecology. Distinguish between populations, communities, ecosystems, biomes and the biosphere. Draw and interpret food chains and food webs. Draw and interpret energy pyramids based upon mass. Identify the various trophic levels. Follow the energy transfers through ecosystems. Differentiate between biotic and abiotic factors in various ecosystems and biomes. Show an understanding of symbiosis by providing examples of the various types of relationships. Demonstrate an awareness of how human activity affects the earth's ecology. V. Strategies Strategies may include: Lecture discussion Power Point Presentations Overhead transparencies Hand outs Demonstrations Smart Board Computer animations, simulations and web quests Laboratory activities Small group discussions Videos Scientific Games Research Model building Digital Projector Debate Dissections Study Guides On line computer tutorials and self evaluations VI. Evaluation Assessments may include: Quizzes /Tests Homework Class work Lab reports Lab Notebook Lab practical Projects Presentations Midterm Final Exam VII. Required Resources A . Recommended Text: Postlethwait and Hopson. Modern Biology. Holt, Rhinehardt and Winston. New York, 2006. On line tutorials and self evaluations, study guides and other associated materials. Additional Resources Greenberg, Jon. BSCS Biology 8th ed.. Glencoe, McGraw-Hill. New York, 2001. Raven and Johnson. Understanding Biology , 3rd ed. Wm. C. Publishers. Boston, 1995. B. VIII. Scope and Sequence Introduction to Biology Scientific Method Microscope What is Life? Ethics Number of Weeks 2 Chemistry of Life The structure of the atom Periodic table Molecules and Ions Bonding pH and solutions Chemical reactions Properties of Water Organic Chemistry 3 Cells Historical development / cell theory Structure / function of organelles Prokaryotic vs. eukaryotic Structure of cell membrane Transport Cell cycle Mitosis and binary fission 4 Photosynthesis and Cellular Respiration3 Overview of process of photosynthesis Structure of the leaf Structure of the chloroplast Pigments Energy transfers and flow of energy Factors affecting rate of photosynthesis Plant adaptations Overview of cellular respiration Anaerobic vs. aerobic Glycolysis, Kreb's cycle, electron transport chain Structure of the mitochondria Endosymbiosis hypothesis DNA and Protein Synthesis DNA / RNA Structure and Function Replication Transcription Translation Repair and mutations Biotechnology 4 Genetics and Heredity Mitosis / development Mendelian genetics Human genetics 5 Evolution and Natural Selection Origin of the earth Darwin Human evolution 3 Classification and Taxonomy 8 Overview of domains Overview of criteria for placement into kingdoms Overview of kingdoms Ecology Sections of the biosphere Food chain and food web Energy pyramid Biotic and abiotic factors Human activity 3 TOTAL 35