AbstractID: 7124 Title: Determination of Complete Orthogonal Wedge Monitor Factor Tables From Single Orientation Measurements The target accuracy of delivered dose is ±5% of planned dose. Accurate dose delivery is important for biological reasons, as a deviation of delivered dose from planned dose can result in poor outcome, either failure to eliminate the tumor or normal tissue complications. For wedged fields, the typical method for calculation of monitor unit setting is to use the open field monitor factor multiplied by the wedge factor. However, the open field monitor factor can deviate from the wedge monitor factor by up to 5%. Measurement of complete monitor factor tables can be time consuming, requiring 2-4 hours per wedge. Furthermore, the time required is doubled by the necessity to measure each wedge in orthogonal orientations. We present a method for calculation of the wedge monitor factor from the monitor factor for the wedge in the orthogonal orientation and the open field monitor factor. Because the phantom scatter for a wedged field of dimension X×Y is the same as that for a field of dimension Y×X with the wedge in the orthogonal orientation, the difference between the monitor factors in the two geometries is due to collimator scatter. The ratio of the monitor factors in the two geometries is the ratio of the collimator scatter for the two jaw settings, which is given by the ratio of the open field monitor factors. Agreement between calculation and measurement is typically less than 0.5% for a variety of wedge angles and field sizes This approach reduces the time required to obtain complete monitor factor tables for wedges by a factor of two.