X This term describes the genetic relationship between individuals of different species, with respect to antigenicity. Idiotype Network Graft-Versus-Host Reaction tor. Elimination of the XRE-element from a promoter abrogates the inducibility of the respective gene by dioxins or other aryl hydrocarbon receptor agonists. Another name for the XRE is dioxin-responsive element, or DRE. Dioxins and the Immune System 3 Xenogeneic 3 3 XSCID Conserved short DNA sequence in the promoter regions of many genes, XRE-elements are the binding site for the ligand complexed aryl hydrocarbon recep- X-linked severe immunodeficiency syndrome resulting in the loss of B and T lymphocyte function because of the dysfunction of multiple interleukin receptors which share a common protein chain. Canine Immune System 3 XRE-Element (Xenobiotic Response Element)