J
JAKS
cooperation with STATs (signal transducers and activators of transcription).
Cytokines
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JAKS are janus kinases, which are cytoplasmic tyrosine kinases that mediate signal transduction by cytokine receptors. JAKS physically interact with cytokine
receptors and are activated by cytokine binding. There
are four known mammalian JAKS: JAK1, JAK2,
JAK3, and Tyk2.
Interferon-γ
Jun NH2-Terminal Kinase
Jun NH2-terminal kinase (JNK) is mitogenic activated
protein (MAP) kinase involved with c-Jun phosphorylation and activation of NF-κB.
Interleukin-1β (IL-1β)
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A family of non-receptor protein tyrosin kinases of
approximately 130 kDa, consisting of JAK1 (Janus
kinase-1), JAK2 (Janus kinase-2), JAK3 (Janus kinase-3), and TyK2 (tyrosine kinase-2).They play a crucial role in the initial steps of cytokine signaling, in
Juvenile Periodontitis
Juvenile periodontitis is an aggressive and destructive
inflammatory disease of the connective tissue of gums
affecting adolescents and young adults.
Chemotaxis of Neutrophils
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Janus Kinase (JAK)