AbstractID: 7654 Title: Anthropomorphic head phantom for MRS localization and
resolution testing
Spectroscopic imaging localization and resolution were evaluated with an anthropomorphic tissue-mimicking (TM) phantom. The
phantom has relaxation times, metabolite concentrations, and coil loading characteristics of the human head allowing use of clinical
pulse acquisition techniques without modification. Single and multivoxel spectroscopic acquisitions were performed with a
commercial 1.5 T MRI system. The phantom uses magnetically TM glass spherical shells to segregate TM materials with different
metabolite concentrations from the TM surroundings. The glass restricts the diffusion of the metabolites while allowing the
spectroscopic image to show the spectral changes across the boundary without susceptibility artifacts. The results show that
localization limits relate to the low resolution of the spectroscopic image. The phantom helps to demonstrate the limits of
spectroscopic imaging localization and has been used for quality control testing and education of interpreting radiologists, referring
physicians, and radiation oncology treatment planners