AbstractID: 8606 Title: Optimization of Compensator Design for Proton Therapy Construction of treatment plans for Proton therapy using passive diffusion through a compensating bolus to create a conformal dose distribution to a target volume is possible through the use of broad beam algorithms, such as those implemented in CMS/FOCUS. However, comparison of the broad beam dose calculations to dose distributions constructed using a pencil beam approach show significant differences at the distal range of the target volume. In a pencil beam approach, the lateral scattering of the individual pencil beams is considered in detail, presenting a significant spread of the pencil beam as it propagates through the patient volume. Such calculations indicate an under-dose to the distal end of the target compared to the broad beam calculation results. This under-dose is significant near regions of high curvature in the target volume, increasing with depth in the patient volume. To compensate for the error in the broad beam calculation, it is necessary to perform a pencil beam calculation to create an optimal dose plan. However, such dose calculations can be computationally expensive and require multiple iterations to optimize. A hybrid routine is being developed to iteratively correct the distal target dose calculation using the pencil beam algorithm along the distal surface of the treatment prescription. The results of the pencil dose calculation are used to modify the compensating bolus to achieve the prescribed dose distribution. Results of this approach will be presented along with suggestions to correct for the lateral scattering of the proton beam deep in the patient.