AbstractID: 6628 Title: Dosimetric Characteristics of New Gafchromic-HS Film With increasing complexity of dose verification for intensity modulated radiation therapy (IMRT), high gradient dosimetry and endovascular brachytherapy, Gafchromic film is an attractive alternative compared to the existing dosimeters. New Gafchromic type HS film eliminates most of the problems associated with the radiographic films. The HS film is 40 µm thick and nearly tissue equivalent (1.1g/cm3) which is sandwiched between two (100 µm) layers of polyester substrate to allow dosimetry measurements in a water phantom. Dosimetric characteristics of HS film (dose linearity, dose rate dependence, energy dependence, orientation, and temperature dependence) are presented in the solid and water phantoms. Our results indicate that HS film is linear between 10-4800cGy and independent of dose rate between 50 cGy/min up to 650 cGy/min. The optical density (OD) of the film is energy independent for all megavoltage photon and electron beams used clinically. The orientational (parallel and perpendicular) response is minimum (2%). The OD of the film is dependent on the temperature of the water phantom at the time of exposure and the duration between exposure and reading time. The OD increases with temperature and falls off at higher (>40°C) temperature. The OD also increases with the duration of reading time. It is concluded that the new Gafchromic-HS film is ideally suited for dosimetric verification in the IMRT, high gradient dosimetry and endovascular brachytherapy. Precautions, however, are needed for the temperature of the medium and the time of readout if in-water measurements are performed.