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The use of x-ray micro-computed tomography (micro-CT) has increased in biomedical
research and industrial applications. This paper presents preliminary results of both
synchrotron radiation (SR) and conventional micro-CT images for hard and soft tissue
samples. A simple SR imaging system based on the principle of phase contrast x-ray
imaging with unmonochromatized synchrotron radiation consists of silicon wafer
attenuators, a tungsten slit, a rotating sample stage, a CdWO4 scintillator crystal, a
charged-coupled device (CCD) detector (1392 x 1040 pixels with 4.65 x 4.65 µm2), and
an image acquisition system. The objects were rotated within the field of view of the
CCD detector. The beam exposure time was 30 msec per projection, and projection data
were obtained at 250 steps over 180 degrees rotation. X-ray CT images were
reconstructed using a simple filtered backprojection implemented with commercial
software of IDL Version 5.1. Three-dimensional images by using SR imaging system
were obtained for both hard tissue (such as tooth) and soft tissue (such as cancerous
breast tissue fixed in formalin) and compared with those obtained with commercially
available micro-CT images using a few micro sized focal spot x-ray source. SR microCT images were comparable to conventional micro-CT images with different imaging
characteristics indicating that SR images may provide more structural details for soft
tissue samples.
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