Practical recommendations M. Neuss, B. Schnackenburg Angiography n General problems n Stents: No solution since stents currently used effectively shield signal from inside the stent lumen. n Timing: It is possible that because of cardiovascular comorbidity not one timing suits all patients with suspected renal artery stenosis. Therefore, we recommend not to use a fixed interval after the injection of contrast agent, but to time on the fly using a 2D time resolved angio. Aorta The approach to imaging of the aorta critically depends on the information available on the suspected pathology. A suspected dissection of the aorta requires a more sophisticated approach than a simple follow-up of a patient with an ectatic ascending aorta. The general recommendation given in this section is suitable for most indications, special indications are dealt with in an addendum. The receiver coil to be used depends on the expected pathology. If there is information available from other imaging modalities that changes are limited to the intrathoracic part of the aorta, we use a five-element phased array coil in a position that is suitable for a cardiac examination. If there is more extensive involvement of the aorta, we use a four-element phased array coil covering the thoracic and abdominal part of the aorta. In very tall patients in which additional information on the anatomy of the iliac arteries is required the use of the coil system built in the magnet may be warranted. The use of parallel imaging techniques is preferred since they reduce breathhold time or increase spatial resolution if breathhold time is kept constant. 20 ml of contrast agent (Gd-DTPA derivate), 20 ml of saline, flow 3 ml/s in both. If extensive aneurysm, increase amount of contrast agent to 25 ml, saline 20 ml, flow 3 ml/s in both. n Scan procedure 1. Survey in SSFP technique, 3 stacks in transverse, sagittal, coronal orientation, 15–20 slices each, slice thickness 8–10 mm, negative gap 1 mm. 2. Stack of transverse slices in SSFP technique covering the area of identified pathology. Slice thickness 8 mm, negative gap 2–4 mm. Spatial resolution 1.5 ´ 1.5 ´ 8 mm (M/P/S). Intrathoracic part of aorta in breathhold or end-expiratory trigger, abdominal part of the aorta in free breathing. If unclear pathology, add stack of oblique sagittal slices in same technique covering ascending aorta, arch, and descending aorta. 3. If significant pathology or first examination acquire proton-density weighted anatomical images in blackblood technique with identical geometry as step 2. 4. Plan MR angiography in an orientation that covers side branches of major interest, i.e., origin of supraaortic branches in thoracic part of the aorta and abdominal branches in abdominal part of the aorta. We use 45–55 slices in a parallel imaging contrast-enhanced 3D-T1TFE-angio technique, slice thickness 1.7–1.8 mm, matrix 352, resulting in a reconstructed voxel size of 1.1 ´ 1.1 ´ 1.7 mm (M/P/S). For the timing of the angiography we use a 2D time resolved angiography started at the injection of the contrast agent. The actual 3D angiography is started at the moment when the contrast bolus enters the region of interest. 5. For printouts of the angiography we reconstruct maximum intensity projections at an angle of 3o. n Measurements that need to be part of the report n Intrathoracic aorta: Aortic sinuses, proximal ascending aorta, aortic arch, descending aorta at the level of the diaphragm, maximal diameter. n Abdominal aorta: Diameter on the level of the diaphragm, celiac trunc, proximal to the iliac arteries, common iliac arteries. If a dissection is present, identify the true and false lumen and check for signs of complication like pericardial or pleural effusion and perivas- cular hematoma. Identification of true and false lumen can usually be accomplished by acquiring the angiography in two dynamics: the first dynamic shows a higher signal intensity in the true lumen, the second dynamic in the false lumen. In cases of doubt use phase contrast angiography to determine flow velocity and direction. In most cases flow in true lumen is faster and in cephalo-caudal direction. If interventional or surgical correction is planned it is important to localize communications of true and false lumen. In many cases this can be done in blackblood technique. If not, use 2D time resolved angiography before 3D angiography with a contrast bolus of 3–5 ml, injection rate 2 ml/s followed by a saline flush to localize the communication between true and false lumen. In aneurysm of the abdominal aorta repair with stent grafts is feasible in many patients. In these cases the distance of the aneurysm from the renal arteries and the diameter of the common iliac arteries need to be part of the report. If the patient had a graft repair before and there is suspected infection of the graft T1weighted blackblood images before and after a single dose of contrast agent need to be compared. A sign of inflammation is contrast enhancement in the tissue surrounding the graft. The prior implantation of stent grafts reduces the signal from inside the stent, but in most stents the struts are spaced wide enough to receive enough signal in spin-echo sequences and gradient echo sequences using contrast enhancement.