AAPM 2004 “Modern Fluoroscopic Equipment Design and Application” Human Vascular System Phillip L. Rauch, M.S. Henry Ford Hospital Detroit, Michigan Human Vascular System PVD Claudation (Exercise induced pain) Deep Vein Thrombosis (Economy class blood clot) Peripheral Vascular Imaging A. Bolus Chase (Native) B. Stepping (Subtraction) 1 Bolus Chase (Native) Human Vascular System Stepping (Subtraction) Human Vascular System 2 Human Vascular System a b c Inferior Vena Cava Filters Human Vascular System Department of Radiology - Division of Physics and Engineering 3 Stent with Balloon Angioplasty Department of Radiology - Division of Physics and Engineering Human Vascular System Basilar-tip Aneurysm Stent with Balloon Angioplasty Department of Radiology - Division of Physics and Engineering Human Vascular System 4 Coil 1 6 Coils 4 Human Vascular System Occlusion Coils Occlusion Micro-coil Occlusion Micro-coil Occlusion Micro-coil 5 Rotational Angiography Fluoroscopic Imaging Department of Radiology - Division of Physics and Engineering Fluoroscopic Imaging Department of Radiology - Division of Physics and Engineering 6 Fluoroscopic Imaging Department of Radiology - Division of Physics and Engineering Fluoroscopic Imaging Fluoroscopic Imaging Department of Radiology - Division of Physics and Engineering Fluoroscopic Imaging X-ray Source Department of Radiology - Division of Physics and Engineering Department of Radiology - Division of Physics and Engineering 7 Fluoroscopic Imaging X-ray Detector Department of Radiology - Division of Physics and Engineering Fluoroscopic Imaging Signal Readout Department of Radiology - Division of Physics and Engineering Fluoroscopic Imaging Notes: Image Display Monitors DO NOT DELETE!!! Image Display Department of Radiology - Division of Physics and Engineering 8 Text Monitor Image Monitors C-arm Control Module Laser Imager Module Image Acquisition Control Module Mouse Keyboard Contrast Injector Control Module System Documentation THE FLUOROSCOPIC IMAGE A radiation field of varying intensity distribution present at the input to the image detector results in an output distribution of visible light which is spatially related to and proportional in intensity to the input radiation distribution Department of Radiology - Division of Physics and Engineering 9 THE FLUOROSCOPIC IMAGE Fluoroscopic Image Fluoroscopic Image: Spatially Modulated Intensity Detector Input Detector Output Iout Iin Intensity I(x,y) (kV, filter, tissue, dose) Relative Contrast (kV, filter, tissue, W/L) (I2-I1) / (I2+I1) Noise (Quantum Mottle-IIIER) (Added Noise: Detector, DAC, ADC, Processing) I1/2 SNR (Geometry, Detector Sharpness I/ x Blur, Processing) (Detector, Processing) Temporal Fidelity I/ t Compensated (Motion, Persistence, Artifact/Distortion I Subtraction) as needed Department of Radiology - Division of Physics and Engineering Digital Sampling Artifact Artifact Distortion Department of Radiology - Division of Physics and Engineering Aliasing Nyquist frequency, fN Equal to half of the sampling frequency (Represents the maximum frequency that a sampled system can accurately handle) Department of Radiology – Division of Physics and Engineering To represent this continuous signal a sample is taken at regular intervals Department of Radiology – Division of Physics and Engineering 10 Aliasing Adequately sampled Sampling at an appropriate frequency Department of Radiology – Division of Physics and Engineering Aliasing Aliasing Sample Original Adequately sampled Sampled signal adequately represents the original signal Department of Radiology – Division of Physics and Engineering Aliasing Sampled Signal is Lower Frequency Undersampled Under-sampling a periodic signal Department of Radiology – Division of Physics and Engineering Undersampled Sample Original Sampling a frequency at an inappropriate rate produces low frequency artifacts (aliasing) Department of Radiology – Division of Physics and Engineering 11 Image Characteristics Visual Perception Department of Radiology - Division of Physics and Engineering Fluoroscopic Image Noise Noise I1/2 SNR Contrast (I2-I1) / (I2+I1) Contrast Sharpness I/ x Sharpness Department of Radiology - Division of Physics and Engineering 12 Noise - Random Low Contrast & Noise Where are the 3’s Integration Level 3 1 2 No Integration Frame Integration (Reduces Noise) Department of Radiology - Division of Physics and Engineering Low Contrast & Noise Department of Radiology - Division of Physics and Engineering Noise - Random Where are the 3’s Low Dose (No Frame Integration) Low Dose (Maximum Frame Integration) Department of Radiology – Division of Physics and Engineering 13 Noise - Random Noise - Random Where are the 3’s Where are the 3’s 4 Frames/sec Department of Radiology – Division of Physics and Engineering 8 Frames/sec Department of Radiology – Division of Physics and Engineering Noise - Random Noise - Random Where are the 3’s Where are the 3’s 15 Frames/sec Department of Radiology – Division of Physics and Engineering 30 Frames/sec Department of Radiology – Division of Physics and Engineering 14 Noise - Random Noise - Random Where are the 3’s Where are the 3’s 4 Frames/sec 4 Frames/sec (With Background Suppression) Department of Radiology – Division of Physics and Engineering Artifact Reduction Digital Subtraction Department of Radiology – Division of Physics and Engineering + = Image Frame (Inverted) Mask (Native Image without Contrast) Department of Radiology - Division of Physics and Engineering Subtracted Image Frame Image Frame (Native Image with Contrast) 15 Digital Native Digital Subtraction Quantum Sink: Detector Landmark (25%) Quantum Sink: Detector Noise Contrast What About Motion? Sharpness Fluoroscopy (0.74 BR/fr) Digital Acquisition (353 BR/fr) Fluoroscopy (0.74 BR/fr) Digital Acquisition (353 BR/fr) 16 Do You See Motion? Department of Radiology - Division of Physics and Engineering Motion Temporal Fidelity Department of Radiology - Division of Physics and Engineering 17 Fluoroscopy – Pulsed vs Cont. Pulsed Fluoro - 30pps (Displayed at 7.5 fps) Image Persistence (Lag) Continuous Fluoro (Displayed at 7.5 fps) Department of Radiology - Division of Physics and Engineering Image Persistence (Lag) Department of Radiology - Division of Physics and Engineering Recursive Filter 1/K Input(n) + Output(n) Z-1 (K-1)/K y(n-1) K = 1.n, 2, 3, 4, 8 Department of Radiology - Division of Physics and Engineering Department of Radiology - Division of Physics and Engineering 18 K=1 (1 Frames) K=2 (10 Frames) Frame 9 contributes 0.2% Frame 5 contributes 3% Frame 2 contributes 25% Recursive Filter K=4 (24 Frames) Frame 18 contributes 0.2% Frame 8 contributes 3% Frame 2 contributes 19% Department of Radiology - Division of Physics and Engineering 19 Sharpness Sharpness X-rays from Point Source Signal Modulation Decreases with Spatial Frequency Department of Radiology - Division of Physics and Engineering Sharpness Signal Modulation Decreases with Spatial Frequency Detector Signal Detector Signal Signal Modulation Decreases with Spatial Frequency Department of Radiology - Division of Physics and Engineering Sharpness Department of Radiology - Division of Physics and Engineering Detector Signal Abrupt Intensity Change at Edge Detector Signal X-ray Intensity Square Wave Resolution Target Signal Modulation Decreases with Spatial Frequency Department of Radiology - Division of Physics and Engineering 20 Edge Restoration 100 20 40 60 80 0% % % Department of Radiology - Division of Physics and Engineering Contrast (Grayscale) Department of Radiology - Division of Physics and Engineering Edge Restoration 0% 100 % Department of Radiology - Division of Physics and Engineering Are the circles the same shade of gray? Department of Radiology - Division of Physics and Engineering 21 Are the circles the same shade of gray? Department of Radiology - Division of Physics and Engineering Are the circles the same shade of gray? Are the circles the same shade of gray? Department of Radiology - Division of Physics and Engineering Fluoroscopy Imaging It’s time for a Pop Quiz…. Department of Radiology - Division of Physics and Engineering Department of Radiology – Division of Physics and Engineering 22 Imaging Quiz #1 What is the diffuse “cloudcloud-like” like” pattern overlying the grid image? Imaging Quiz #1 Fluoroscopic Image Pattern Recognition Department of Radiology – Division of Physics and Engineering 23 Imaging Quiz #2 Imaging Quiz #2 #1 #2 Which one is the quarter? Department of Radiology – Division of Physics and Engineering Imaging Quiz #2 Which one is the quarter? Department of Radiology – Division of Physics and Engineering Imaging Quiz #2 #3 Which one is the quarter? Department of Radiology – Division of Physics and Engineering #1 #2 #3 Which one is the quarter? Department of Radiology – Division of Physics and Engineering 24 Imaging Quiz #2 #1 #2 Imaging Quiz #2 #3 Which one is the quarter? Department of Radiology – Division of Physics and Engineering Pattern Recognition #1 #2 #3 Which one is the quarter? Department of Radiology – Division of Physics and Engineering Imaging Quiz #3 Does Orientation Matter? Who are these persons? Department of Radiology - Division of Physics and Engineering Department of Radiology – Division of Physics and Engineering 25 Imaging Quiz #3 Imaging Quiz #3 Bill Gates Bill Gates Department of Radiology – Division of Physics and Engineering Abraham Lincoln?? Department of Radiology – Division of Physics and Engineering Quiz #4 Which is a darker shade of gray? B A 26 They are the same shade of gray!! They are the same shade of gray!! They are the same shade of gray!! 27 Imaging Quiz #5 What is this? They are the same shade of gray!! B Noise Contrast Temporal? A Imaging Quiz #5 What is this? Noise Contrast Temporal Imaging Quiz #5 What is this? Noise Contrast Temporal 28 Imaging Quiz #5 What is this? Noise Contrast Imaging Quiz #5 What is this? Temporal Imaging Task What is this? Department of Radiology – Division of Physics and Engineering Noise Contrast Temporal Imaging Task What is this? This task is difficult because the image is presented out of context Department of Radiology – Division of Physics and Engineering 29 Imaging Task What is this? Image presented in context Department of Radiology – Division of Physics and Engineering Human Visual System Able to recognize patterns of motion in the presence of noise Since fluoroscopy is utilized for motion studies, we can allow greater amounts of image noise while still being able to recognize anatomical patterns in the image It is important to assure that temporal fidelity is maintained Department of Radiology - Division of Physics and Engineering Imaging Task What is this? Same image, different context Department of Radiology – Division of Physics and Engineering Last Imaging Quiz How can you increase the IIIER (and thereby improve the quantum statistical noise), yet simultaneously reduce the entrance exposure rate to the patient? How can you do the above, while preserving or even improving tissue contrast, and overall image quality? How can image processing be detrimental to the goals of the procedure? Department of Radiology - Division of Physics and Engineering 30 Last Imaging Quiz Stay tuned…… Attend the other courses in this series Thank you for your attention in my class Best wishes in your continued studies and for your career in Medical Physics --Phil Rauch (philr@rad.hfh.edu) Department of Radiology - Division of Physics and Engineering 31