Figure 3: Focal transplantation results in extensive
myelination at the site of implantation. An md rat was
transplanted at 7 days of age with a dissociated cell
preparation from the spinal cord of a normal rat and perfused
11 weeks later. In (a) myelin produced by the transplanted
cells can be seen in the dorsal and ventral (right) columns
(arrows). The gray matter on the right side of the cord is
also myelinated. On higher power in (b) and (c) large areas
of myelin can be seen adjacent to areas in the dorsal column
(b) and the left ventral column (c), that have remained
nonmyelinated. Myelination by the transplanted cells is seen
many millimeters rostral and caudal to the segment shown
in (a). (Modified with permission from Zhang and Duncan,
1999).