PPS STUDENT ABSTRACTS, SEPT 2013-AUG 2014
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PPS student
PPS faculty member
PHARMACEUTICS
American Association of Pharmaceutical Scientists, November 10-14, 2013, San
Antonio, TX.
Shah P, Mallick P & Ghose R. Taxol alters gene expression of drug metabolizing
enzymes by TLR4 dependent mechanism in vitro.
Shah P, Gandhi A & Ghose R. Altered irinotecan pharmacokinetics and toxicity in dietinduced obesity.
Wu L, Chow DS-L & Putcha L. Population pharmacokinetics of intranasal scopolamine.
Basu S & Hu M. Inactivation of active toxic metabolite of anticancer drug irinotecan by
plant UGT enzyme expressed E. coli: An in vitro and in vivo study.
Cui L, Zhou M, Xiong C, Li C & Chow DS-L. Integrin αnβ3-targeted [64Cu]CuS
nanoparticles for PET/CT imaging and photothermal ablation (PTA) therapy.
Samant T, Tu S-M, Navone N, Yang J & Chow DS-L. Efficacy of subcutaneous
diethylstilbestrol nanosuspension formulation in an MDA PCa 183 xenograft mouse
model.
Gadgil P & Chow DS-L. Formulation and characterization of Lazaroid loaded solid lipid
nanoparticles.
American College of Clinical Pharmacology, October 13-16, 2013, Albuquerque,
NM
Wu L, Chow D, & Putcha L. Impact of gender difference on pharmacokinetics of
intranasal scopolamine
Wu L, Chow D & Putcha L. Population pharmacokinetics of intranasal scopolamine
Others
Shah P, Gandhi A & Ghose R. Altered irinotecan pharmacokinetics and toxicity in dietinduced obesity. Experimental Biology, April 26-30, 2014, San Diego, CA.
Shah P*, Omoluabi O, Guo T & Ghose R. Role of TRIF and MAP Kinases in TLR3 & 4
mediated regulation of drug metabolizing enzymes and transporters. Society of
Toxicology, March 23-27, 2014, Phoenix, AZ.
Graduate Student Travel Award, Society of Toxicology
Third place, best abstract competition
Highlighted on ASPET web site http://www.aspet.org/Blog.aspx?id=5234&blogid=219
PHARMACOLOGY
Experimental Biology, April 26-30, 2014, San Diego
Al-Sawalha N, Senny C, Hernandez A, Valdaez D, Pokkunuri I, Thanawala V, Bond R
& Knoll B. Role of cAMP signaling in mucin production in response to IL-13 in human
bronchial epithelial cells.
Suryavanshi S, Singh S & McConnell B. Gravin-mediated PKC signaling in heart.
Singh S, Diaz Diaz A, Wijaya C, Suryavanshi S, Fan Q & McConnell B. Gravin mutant
mice show resistance to the development and progression of cardiac hypertrophy.
Rababa'h A, Singh S, Wijawa C, Pinkaew D, Fujise K & McConnell B. Calcium cycling
transient parameters in fortilin-deficient mice.
Patki G, Solanki N, Alkadhi I, Allam F & Salim S. Potential role of anxiety and stress in
aggressive behavior in rats.
Martinez L & Tejada-Simon M. Targeting hyperactive Rho GTPase regulatory proteins
in autism.
Society for Neuroscience, November 9-13, 2013, San Diego
Eriksen J, Vollert C, Forkuo GS & Bond RA Chronic treatment with an adenosine α1
antagonist worsens long-term memory.
Dao A, Zagaar M, Salim S & Alkadhi K. Regular exercise prevented hippocampal LLTP impairment and aberrant alterations in levels of L-LTP related signaling molecules
in Alzheimer’s disease-like pathology.
Solanki N, Patki G, Atrooz F, Allam F, Ansari A, Jannise B, Maturi J & Salim S.
Preventive effect of moderate treadmill exercise on social defeat- associated cognitive,
behavioral and biochemical impairments in rats.
Ohia O, Vollert C, Berridge C, So SP, Ruan K-H & Eriksen J. Prostacyclin synthaseoverexpression in mice impacts memory and anxiety-like behavior.
Vollert C, Gregory S, Ngo K, Pourzargham H & Eriksen J. Behavior and
neuropathology in a progranulin haploinsufficient mouse model.
17TH WORLD CONGRESS
TOWN
OF
BASIC & CLINICAL PHARMACOLOGY, JULY 13-18, 2014, CAPE
Forkuo G, Thanawala VJ, Knoll BJ & Bond RA. The role of the β2-adrenoceptor Gs
pathway in the development of the asthma phenotype in murine models.
Thanawala, VT, Valdez D, Al-Sawalha N, Forkuo GS, Knoll BJ & Bond RA. The
signaling-bias of certain β-blockers predicts their therapeutic efficacy in a murine
asthma model.
15th International Winter Eicosanoid Conference, March 9-12, 2014 Baltimore, MD
Akasaka H, So S-P & Ruan K-H. Structural and topological mechanisms of
inflammatory prostaglandin E2 biosynthesis in the ER environment.
Nikhar S, Chillar A & Ruan K-H. Identification of initial lead compound targeting
inflammatory PGE2 receptor by integrated virtual and high throughput screening.
41st Annual MALTO Medicinal Chemistry and Pharmacognosy Meeting, May 1820, 2014 Memphis, TN
Nikhar S, Akasaka, H & Ruan K-H. Identification of initial lead compound targeting
inflammatory PGE2 receptor by integrated virtual and high throughput screening.
Akasaka H, Nikhar S, & Ruan K-H. Structural characteristics of inflammatory
microsomal prostaglandin E2 synthase-1 revealed by identified novel lead compounds.
9th Adrenoceptor/GPCR Sir James Black Conference, July 19-23, 2014, Kruger
Natl. Park, So. Africa
Thanawala, VT, Valdez D, Al-Sawalha N, Forkuo GS, Knoll BJ & Bond RA. The
signaling-bias of certain β-blockers predicts their therapeutic efficacy in a murine
asthma model.
Forkuo GS, Thanawala VJ, Knoll BJ, Bond RA. The role of the β2-adrenoceptor Gs
pathway in the development of the asthma phenotype in murine models.
Others
Martinez LA & Tejada-Simon MV. Targeting hyperactive Rho GTPase regulatory
proteins in autism. Biology of Behavior Institute, May 3, 2014, Houston, TX.
Martinez LA & Tejada-Simon MV. Normalizing critical phenotypes in Fragile X
syndrome using novel inhibitors of small GTPases. 14th International Fragile X
Conference, July 16-20, 2014, Orange County, CA.
Nguy S, Martinez LA & Tejada-Simon MV. Characterization of behavioral deficiencies
in FMR1-KO female mice. Undergraduate Research Day, October 10, 2013, University
of Houston, Houston, TX.
Le T, Nguy S, Ray S, Martinez LA & Tejada-Simon MV. Effects of the inhibition of
isoprenylation in the mouse brain. Undergraduate Research Day, October 10, 2013,
University of Houston, Houston, TX.
Nguy S, Martinez LA, Ray S & Tejada-Simon MV. Rac1 inhibition ameliorates observed
cognitive deficits in FMRP-deficient female mice. Society for the Advancement of
Chicanos and Native Americans in Science, Annual Meeting, October 3-6, 2013, San
Antonio, TX.
Martinez LA & Tejada-Simon MV. Use of novel pharmacological agents to assess the
role of Rho GTPase regulatory proteins in Fragile X syndrome. FRAXA Investigators
Meeting, September 29-October 2, 2013, Southbridge, MA.
Zhou L, Chen Z, Vanderslice P, Savage MM, Warier ND, Akasaka H, Ruan K-H,
Willerson JT & Dixon RA. Prevention of monocrotaline-induced pulmonary arterial
hypertension by intramuscular injection of a naked plasmid expressing a fusion protein
with combined cyclooxygenase-1 and prostacyclin synthase activities. American
Thoracic Society International Conference, May 16-21, 2014, San Diego, CA
Dhande IS, Hussain T. Angiotensin AT2 Receptors exert an anti-inflammatory response
in lipopolysaccharide-activated THP-1 macrophages. High Blood Pressure Research
Scientific Sessions, September 11-14, 2013, New Orleans, LA