ABSTRACT: Physico-chemical properties of MgO depend on the method of preparations. MgO with (100) rock salt structure contains surface cavity and defects that are important for their chemical reactivity. In this study, nano structured MgO is prepared by hydration and dehydration method. Its chemical characterize is then translated into its basic strength using back titration method. This study also shows that there comprise two basic sites at the prepared sample; MgOH and MgO centres. As the nano structured MgO were prepared, more surface cavity and defect were present, thus, exposing more O2-, which influence the more basic strength. Finally it was found that the basic strength is the highest when the sample nano structures MgO prepared at temperature higher than 500°C.