startscreen contents Introduction search hitlist help 1 Introduction The human community is not a constant “arrangement” of living persons. In contrast, it can be considered a living system which is based not only upon man itself but on several influencing factors. These include the density of population, the extent of technological development, the professional specialization within a population, and the development of the general environment, such as the weather or the oxygen and carbon dioxide concentrations in the air. There is no doubt that the total human population has increased exponentially since the development of the technology to use extra-human and extra-mammalian energy for specific human purposes such as food supply, housing, and transportation. The so-called technical decades are characterized by at least two main features: 1. The access to and use of non-biological, i.e., physical and chemical energy sources 2. Changes in the “real” environment, and a broad neglect of the virtual world. Even at a time when some of the most difficult questions in the understanding of the physical environment were being analyzed, knowledge of the basic laws within the human virtual world was quite poor. Freudian theory was accepted by the medical world after Einstein’s theory of relativity in the natural sciences! This is not surprising as the only access to the virtual world is by communication. Communication, again, is based upon changes in a system, especially upon movements. Thus, with increasing transportation of goods and human migration the need for more sophisticated and reliable communication increased. Unlike the arrangement of any living system which is clearly separated from its environment, communication usually occurs in an analogous manner. The natural and basic communication system of man is audio, or speech, and hearing. The second is visual. Speech is a time-dependent communication system, visual information and can be time dependent (movements) or time independent (images). The first and finally successful attempt to make acoustic information independent of time was the creation of a script. The translation of audio into visual information, or of a speech into a written document, was the first successful technique to maintain acoustic information over a long period of time. This procedure can be considered to be equivalent to digitalization of an analog source of information. It is an elegant and asynchronous solution of acoustic information storage. The data and speed of reading a document are completely independent of the time needed for writing and the date it was written. The technical development of analog storage of acoustic information such as tapes, disks, or CDs has the advantage that the original “note,” “temperature” or “color” have been 2 Telepathology preserved. It is still asynchronous. However, the speed of playing a tape or disk has to be equal to that of recording. Whereas man has a long experience of “storing” acoustic information, and using it for further future purposes, the storage of visual information has been more difficult. Although there are impressive examples of “stored” images reaching back several thousands of years, it is not clear whether these images represent a “figure” of the environment, or the “beliefs” and “thoughts” of ancient people translated into certain visual impressions of their environment. In subsequent cultural epochs the visual storage of important events of man was performed by sculpture and painting. Interestingly, the artists tried to include certain “nonreal” components into their work in order to maintain or allow an insight into their own or environmental feelings, i.e., “visual translated or virtual” world. The development of photography and its technical perfection was the next important step to ensure that visual information could be kept for years. It permits a “real” and “non-biased” storage of time-independent spatial arrangements in our environment, adjusted to the way most of us “see our world.” At the same time it was realized that storage and evaluation of visual information is one of the most important and practicable medical techniques for detecting and classifying a disease, and for treating the patient. These sources not only include “real” images such as those taken from a microscope or chest X-rays. All data obtained from “measurements,” which might include blood serum levels, ECG curves, antibody levels or lung function tests, are transformed into visual information, and not into audio. The more technical methods of detecting or classifying a disease are available the greater the visual information will become. An increase in information increases the need for appropriate storage and retrieval; otherwise it is inaccessible and useless. Storage and retrieval of information are the columns of communication. Medical communication is more efficient and less biased when visual information can be stored, retrieved, and transmitted. It is important to recognize that several “levels” within these visual data exist in respect to the disease and treatment of patients. These levels are not fixed, depend upon the nature of the disease, and, in addition, are subject to the development of medical progress. The existence of these "information levels” reflects the handling of data, for example, in a relational data bank. These information levels need to be connected, and procedures to import, handle and display the data have to be developed. In other words, communication between visual information at different priority levels causes the need for introduction of a “second order communication,” which is comparable to the creation of “second order statistics.” It is often appropriate to retranslate the “second order information” not directly into the “real world”, i.e., to present the data obtained by application of certain “display rules,” but to present data obtained from calculations of numerous “similar” cases, and to search for the most probable diagnostic and therapeutic solution. These calculations most frequently use multivariate discriminant analysis, or neural network applications, and can be performed independently of the location of the patient or the date of data input. Thus, we enter the virtual world, an environment which is only “real” in a set of visual discrete information blocks, blocks that are used to store and handle real information according to various, not precisely defined aims. In medicine, the first step is to ensure that all the Introduction 3 available information on a patient is incorporated in a patient file which consists of personal data, symptoms, findings, images, treatment procedures, and outcome. To collect this information is not easy and usually requires a distributed information network. These can be hospital based, the data obtained by a house physician, and can be fed in physically in different forms, either by direct access to the information system, or by a physically separated “electronic card " which might be equivalent to the commercial credit card system. Although suggestions abound as to how these systems could work, and what kind of effort would be involved to run them, the details have yet to be worked out. In addition, the technical progress which affects these system to a high degree is extremely rapid. The power and capability of the modern computer has not yet reached its peak, and the creation of modern image archive systems, including high-resolution image acquisition systems, is still in its infancy. What are the most important rules or constraints of modern communication in medicine? What are the needs of the doctors, the administration, the diagnostic laboratories, or the surgical theaters in respect to these changes? What are the most promising ways to take advantage of these developments, and which seem to be less efficient? These questions can only be accurately answered if a basic understanding of information uptake, processing, and release is taken into account. next