AbstractID: 10113 Title: CT Imaging of the Breast with a Novel New System Historically, the use of Computed Tomography for imaging breast tissue in the USA has been relegated to determining local/ regional breast cancer recurrence and extent of disease. The primary reasons for its’ lack of use in the detection and diagnosis of breast cancer have been identified as inferior image quality, high radiation dose, inability to cover the entire breast and difficult patient positioning. In 1975, a custom designed CT for Breast was developed by General Electric and underwent extensive clinical study at the Mayo Clinic and the University of Kansas Medical Center. While initial results were most promising, the product never came to market due to high dose, poor resolution and use of IV Contrast. As such, mammography has grown to be the gold standard in breast imaging. In the mid 1990s’, research in Cone beam CT for breast imaging was underway at UC Davis and University of Rochester Medical Center. Prototypes of dedicated Cone Beam CT Scanners for the breast have been developed at both institutions with more than favorable results compared to mammography in radiation dose, coverage of the breast tissue and image quality. With multislice/ multiplaner and 3D capability, Cone Beam CT surpasses 2D projection imaging as a viable diagnostic tool and has the potential to become a commercial success. This lecture will present the clinical results of an dedicated Cone Beam CT for breast imaging and it’s comparison to digital mammography. Educational Objectives: 1- Understand the current use of CT in Breast Imaging and its limitations 2- Understand the development history of CT imaging of the breast. 3- Understand the diagnostic value and capabilities of a modern dedicated Cone Beam CT for Breast Imaging