Functions of Cardiovascular system system circulates blood throughout body • transports energy substrates (glucose, FA, ect.), electrolytes and hormones to tissues • removes waste products lactate, CO2 & H2O thermoregulation Heart heart rate mass: • average • untrained horse • trained 1.0% 0.94% 1.1% greyhound • heart size of a clenched fist • located in the chest • weighs about 1% of its BW Heart located in thoracic cavity approx. 9-10 lbs (1% of BW) split into left and right halves • both contain an atria and a ventricle • left side circulates blood to systemic system • right side circulates blood to the pulmonary system systole - contraction diastole - relaxation aorta has elastic walls pulse • expand during systole • recoil during diastole arteries/arterioles have muscular walls allowing for vasoconstriction and vasodilation • blood pressure increases when the walls of the arteries constrict Capillaries Constructed of permeable walls sight of gas, nutrient and waste product exchange • pulmonary capillaries discard CO2 and extract O2 from the alveoli of the lungs capillaries are very small in diameter • RBC flow through single file (blood is sluggish if the PCV is high) conditioning (training) can increase capillary density 50% • provides more efficient O2 delivery Venous System venules and veins have lower blood pressure than arteries horse legs have valves to provide unidirectional blood flow in veins venous flow depends on muscle contractions • activity provides better venous blood movement • inactive - blood pools in extremities “stocking-up” • accumulation of fluid in legs Blood 10% of horse BW of about 40 liters at rest • pulmonary circulation 20% • heart, arteries and arterioles 15% • venules and veins 60% blood is comprised of plasma and cells • plasma: 55% of the total blood volume 91% water and 9% solids (proteins) • albumin, globulin and fibrinogen Blood Cell Composition red blood cells (RBC) - erythrocytes - contain hemoglobin • manufactured from bone marrow • life span of 100-120 days white blood cells (WBC) - leukocytes - fight infection • manufactured in the spleen • renewed every 10 days • 5 types neutrophils (50-60%), eosinophils (2-5%), basophils (<1%), monocytes (5-6%), lymphocytes (30-40%) platelets - thrombocytes - clot blood • life span of 5-9 days Blood Analysis blood scan: 5 minutes • for major changes from normal (PCV, total protein, hemoglobin and estimate white blood cell count) full blood count: 30 minutes • main count of WBC’s to detect infection, stress, allergies, ect. blood profile: 24 hours • detailed RBC count, individual WBC counts, enzymes, electrolytes, ect. Plasma - fluid spun from unclotted blood serum - blood is allowed to clot and fluid is spun from the clot (contains no fibrinogen) Spleen About 1% of BW splenic contraction • 1/3 to 1/2 RBC stored in spleen at rest • hematocrit or packed cell volume (PCV) rest 35-45% maximum 60-65% • hemoglobin content of extra RBC in the blood acts as a pH buffer, enabling horses to tolerate extremely high blood lactate concentrations Function During Exercise Heart rate - bpm • resting HR 25-45 bpm • maximal HR 240 bpm desirable cardiovascular features • large, muscular heart • low resting HR • high maximal HR HR: 20-110 • not very predictable intensity of work • 120 (low),160 (moderate), 200 (intense) steady state 2-3 minutes • regulated by sympathetic nervous activity and/or hormones steady state constant during sub-maximal work continual increase in HR with intense exercise (warm-up) monitor HR - indication of any problems Fatigue • 170 bpm 24 min • 205 bpm 4 min cardiovascular drift