AbstractID: 8072 Title: SRS/SBRT Planning, QA and Clinical Applications on Linacs on Everything that's not a CyberKnife or GammaKnife Abstract Stereotactic radiosurgery has become the standard of care in the treatment of many cranial neoplasms. This success has stimulated significant interest in the application of such an approach for the treatment of extracranial tumors. With the development of image guidance technologies, there is a possibility that rigid-head fixation can be eliminated; image guidance is also accelerating the clinical implementation of the approach in extracranial sites. An essential prerequisite of “frameless” stereotactic systems is that they provide localization accuracy consistent with the safe delivery of a therapeutic dose of radiation given in one or few fractions. In this presentation we will review linac-based SRS/SBRT technologies for technologies with particular emphasis on the quality assurance aspects associated frame-based and frameless localization with establishing and maintaining a clinical program Educational Objectives Understand localization principles for linac based radiosurgery Review quality assurance processes for frame-based and frameless radiosurgery