CurriculumVitae:JamesA.Carson TableofContents Background Education ……………………………………………………… ProfessionalService ……………………………………………………… EmploymentHistory ……………………………………………………… Publications PeerReviewedPublications ……………………………………………………… LiteratureReviews/BookChapters ……………………………………………………… PresentedAbstracts ……………………………………………………… StudentMentorship HighSchoolResearch ……………………………………………………… UndergraduateFellows ……………………………………………………… Awards:HighSchool&Undergraduate ……………………………………………………… ChairUndergraduateHonorsThesis ……………………………………………………… MentoredUndergraduatePrograms ……………………………………………………… DoctoralStudentSupervision ……………………………………………………… MastersStudentSupervision ……………………………………………………… MentoredGraduateFellowships&Grants……………………………………………………… MentoredGraduateAwards ……………………………………………………… ResearchGrants Pending/Active ……………………………………………………… CompletedGrantFunding ……………………………………………………… Submissionsnotfunded ……………………………………………………… Presentations SpeakingPresentations ……………………………………………………… Instructional/ServicePresentations ……………………………………………………… Teaching RecentCoursesTaught ……………………………………………………… CoursesDeveloped ……………………………………………………… Service University ……………………………………………………… SchoolofPublicHealth/Department ……………………………………………………… Professional/Community ……………………………………………………… Certifications ……………………………………………………… 1 Page2 Page3 Page4 Page5 Page10 Page11 Page14 Page16 Page17 Page18 Page19 Page20 Page22 Page23 Page24 Page25 Page26 Page29 Page31 Page35 Page36 Page37 Page39 Page40 Page42 Page43 CurriculumVitae JamesA.Carson Professor Chair,ExerciseScienceDepartment AssociateDirector,TheCenterforColonCancerResearchatUSC Director,TheIntegratedMuscleBiologyLaboratory DepartmentofExerciseScience ArnoldSchoolofPublicHealth UniversityofSouthCarolina PublicHealthResearchCenter,Rm.301,921AssemblyStreet,ColumbiaSC29208 Phone:Office:(803)777-0809;Lab:(803)777-0142 carsonj@mailbox.sc.edu Education B.S.1985 Ph.D.1993 BusinessAdministration,InsuranceandRiskManagement,TheOhioStateUniversity, Columbus.Ohio ExerciseScience,CollegeofEducation,TheOhioStateUniversity,Columbus. StephenE.Alway,Ph.D.,Advisor; DissertationTitle:Theeffectofagingonfibernumberandsatellitecellactivationinthe anteriorlatissimusdorsimuscleoftheJapanesequailafterstretchoverload. AttendedtheUniversityofAkron,MasterofBusinessAdministration(M.B.A)Graduate Program1986.Completed6hoursofgradedcourseworkrelatedOrganizationalBehavior& Management.LefttheprogramtoattendGraduateSchoolatOhioState. ProfessionalTraining Post-DoctoralResearchFellow,1993-1997.Dept.ofIntegrativeBiology,Pharmacology,andPhysiology, UniversityofTexasMedicalSchool,Houston. PrincipalInvestigator:FrankBoothPh.D. NRSANIHPost-DoctoralFellowshipAwardedtoJamesCarson:Skeletalα-actinpromoterfunctionduring hypertrophy. Post-DoctoralResearchFellow,1997–1999.HuffingtonAgingCenter/DepartmentofCellBiology,Baylor CollegeofMedicine,HoustonTX.PrincipalInvestigator:RobertJ.Schwartz.Ph.D. ProfessionalMemberships DeltaOmegaSociety–HonorarySocietyinPublichealth AmericanCollegeofSportsMedicine(ACSM) AmericanPhysiologicalSociety(APS) NationalStrength&ConditioningAssociation(NSCA) 2 Awards • DistinguishedResearchLeadershipAward,SouthCarolinaGovernor’sSchoolforScienceandMathematics, 2016.Recognitionforsuccessfulmentoringofhighschoolstudentsummerresearch. • DeltaOmegaSociety–MuChapter,InductedintotheHonorarySocietyinPublicHealth,2015 • “STAR”ReviewerAwardforExcellenceinPeerReviewfor2011–AmericanPhysiologicalSociety • ArnoldSchoolofPublicHealthFacultyResearchAward,forexcellenceinhealthresearch,2009 • ACSMFellowstatus(FACSM),awarded2008,AmericanCollegeofSportsMedicine • NominatedfortheArnoldSchoolofPublicHealthKeithTeachingAward,2004,2009,2012,2013. • NominatedfortheUniversityofSouthCarolinaKeyAwardforIntegratingUndergraduateTeachingand Research,2007. • VarsityletterFootball,TheOhioStateUniversity,1981,1982,1983 o Linemenoftheweek,OhioStatevs.Illinois,1982;IronmanAwardOhioStateFootballFall1982 ProfessionalService ProfessionalOrganizations • • • • • • • • AmericanCollegeofSportsMedicineResearchAdvisoryCommittee,2006–2009 AmericanCollegeofSportsMedicineScienceIntegration&Leadership,Committee.2009–12 NominatedtorunforACSMBoardofTrusteeselection(notelected),2013 Co-chair2014ACSM/APSIntegrativeExerciseMeeting,Appointed,2013-14 MuscleBiologySteeringCommittee,AmericanPhysiologicalSociety,Appointed.2012–Present ExercisePhysiologyCouncilor,Environmental&ExerciseSection,AmericanPhysiologicalSociety.Elected2012–15. Diversity&LeadershipTrainingProgram,AmericanCollegeofSportsMedicine.2013–Present ExecutiveBoard,SoutheastChapterofAmericanCollegeofSportsMedicine(ACSM).Elected2014-Present EditorialDuties • • • • EditorialBoard,JournalofAppliedPhysiology,1999–2002 EditorialBoard,Exercise&SportsScienceReviews,AmericanCollegeofSportsMedicine.2011–2014 EditorialBoard,AmericanJournalofPhysiologyIntegrative&Regulatory.2009–Present EditorialBoard,JournalofAppliedPhysiology,2013-Present • • • • • • • • • • MidAtlanticAmericanHeartAssociationGrantReviewCommittee:MolecularSignaling,2003-2005 WorldCancerResearchFund(WCRF)researchgrantAdHocreview,2011 FrenchMuscularDystrophyAssociation(AFM)GrantReview,2011 NASAGrantReviewPanel:MuscleStudySection,2012 VeteransAffairsCellular&MolecularMedicineGrantReviewPanelMember,2013–Present MichaelSmithFoundationforHealthSciences,BritishColumbia,reviewer,April2014 NIHSMEPStudySectionexternalreviewer,June2014,October2014 NIH/NCIProvocativeQuestions:CancerTherapiesandOutcomes,reviewer,March2013,October2014 NIH/NCITumorBiologyStudySection,externalreviewer,June2015 NIH/CSRFellowshipReviewPanel,October2015 GrantReview UniversityService(selected) • • • • • • • • UniversitySCVPResearchAspire-IReviewCommittee,2014 FacultyadvisorforSouthCarolinaClubFootballStudentOrganization.2010–2014. University-wideNIHFellowshipsAdvisor,USCFellowships&ScholarPrograms,2013–Present. UniversityCommitteeonTenureandPromotion(UCTP).ELECTED,3-yearterm.2013–2016. UniversityAthleticsAdvisoryCommittee.ELECTED,3-yearterm,2013–2016. FacultyadvisorforExerciseScienceMajorsClubStudentOrganization,2013–Present. IntegratedBiomedicalSciencesGraduateProgramSteeringCommittee.Appointed.2010–Present AnimalCareUsersGroup.Appointed.University-widecommittee,2010–Present 3 • FacultyadvisorforSouthCarolinaClubLacrosseStudentOrganization.2104-Present. • JudgefortheJuniorScience&HumanitiesSymposium.2010,2011,2012,2014,2105 • InstitutionalAnimalUseandCareCommittee,Presidentappointed.2001through2009. OtherService(selected) • • • ExternalDoctoralDissertationreviewerandcommitteemember,YorkUniversity,Toronto,AyeshaSaleem,2013 DiversitymentorACSMNationalMeeting2013&2014,PhDstudentBridgetPeters,AuburnUniversity, APSFrontiersinPhysiologyProfessionalDevelopmentMentor,BetsyScarborough,MiddleSchoolTeacher Richland1SchoolDistrictColumbiaSC,2004 Employment Chair,ExerciseScienceDepartment,UniversityofSouthCarolina October2014-Present InterimChair,ExerciseScienceDepartment,UniversityofSouthCarolina August–September2014 AssociateDirector,TheCenterforColonCancerResearchattheUniversityofSouthCarolina. 2013–Present Professor,ExerciseScience,ArnoldSchoolofPublicHealth,UniversityofSouthCarolina, 2011–Present Director,GraduateStudiesforExerciseScience,U.ofSouthCarolina. 2007–2014 AssociateProfessor(withTenure),ExerciseScience,ArnoldSchoolofPublicHealth,U.ofSouthCarolina, 2005–2011 DivisionHead,DivisionofAppliedPhysiology,ExerciseScienceDepartment,U.ofSouthCarolina, 2004-2008 AssistantProfessor(TenureTrack),ExerciseScience,ArnoldSchoolofPublicHealth,U.ofSouthCarolina, 1999–2005 Post-DoctoralResearchFellow,CellBiology/HuffingtonAgingCenter,BaylorCollegeofMedicine,Houston 1997–1999 Post-DoctoralResearchFellowPhysiologyandCellBiologyDept.,UniversityTexasMedicalSchool,Houston. 1993-1997 GraduateResearchAssistant,ExerciseScience,TheOhioStateUniversity,ColumbusOhio. 1991–1993 GraduateTeachingAssistant,ExercisePhysiology,TheOhioStateUniversity,Columbus,Ohio. 1989-1991 GraduateAssistantCoach,Strength&ConditioningforVarsityfootball,men’s&women’sbasketball,and icehockey.TheOhioStateUniversityAthleticDepartment,Columbus,OH., 1987-1989 Management,YellowFreightInc.,Cleveland,Ohio, 1985-1987 PersonalStatement: My"IntegrativeMuscleBiologyLaboratory"employsmolecularbiologytechniqueswithinvivoandinvitro modelsexaminingmuscleplasticity.Wehavebeenexaminingtheregulationofmusclewastingwithcancer cachexia.Weareexaminingtheimportanceofmusclemetaboliccapacityonproteinturnoverand apoptosisregulationduringinitialandseverestagesofwasting. 4 Scholarship:Peer-ReviewedPublications SCOPUSAuthorID:7201381039,h-index32;2,601citations;October16,2015 GoogleScholar:Currenth-index38;Citations:3,692;10-index:66;ReportJanuary4,2016 10articlescitedover100times *denotesmentorship:USCstudentorpost-docauthorcontribution(italicsdirectJ.Carsonsupervision) +denotesleadership:correspondingauthor/seniorauthor $ BOLDreference:highlycitedarticle(over100citations) Inreview:2manuscripts;InPreparation:5manuscripts Published/InPress:CitationsGoogleScholar,journalimpactfactoris5yr.attheyearpublished 2015 79.GaoS*,andJ.A.Carson+.LewisLungCarcinomaRegulationofMechanicalStretch–InducedProteinSynthesisin CulturedMyotubes.AmJ.Physiol.Cellinpress2015 -Impactfactor3.94(5yr.) 78.Hardee,J.P.*,J.E.Mangum*,S.Gao,S.Sato*,K.L.Hetzler*,M.J.Puppa*,D.K.Fix*,andJ.A.Carson+.Eccentric Contraction-InducedMyofiberGrowthinTumor-BearingMice.J.ApplPhysiolinpress2015-Impactfactor3.77(5yr.) 77.Hetzler,K.L.*,J.P.Hardee*,M.J.Puppa*,A.A.Narsale,S.Sato*,J.M.Davis,andJ.A.Carson+.SexDifferencesin theRelationshipofIL-6SignalingtoCancerCachexiaProgression.BiochemicaBiophysicaActa:MolecularBasisfor Disease.1852(5):816-252015.PMCID:PMC4372501.-Impactfactor4.97(5yr) 76.Narsale,A.A.*,R.T.Enos*,M.J.Puppa*,S.Chatterjee,E.A.Murphy,R.Fayad,M.O.,Pena,J.L.Durstine,andJ.A. Carson+.LiverInflammationandmetabolicSignalinginApcMin/+mice:Theroleofcachexiaprogression.PLOSOne015 Mar19;10(3):e0119888PMCID:PMC4366213–ImpactFactor3.70(5yr) 2014 75.Puppa,M.J.*,S.Gao*,A.A.Narsale*,andJ.A.Carson+.SkeletalMuscleglycoprotein130sroleinLewisLung carcinoma-inducedcachexia.FASEBJournal28(2):998-10092014.PMCID:PMC3898653-impactfactor6.22(5yr) 74.Velazquez,K.T.*,R.T.Enos*,A.Narsale*,M.J.Puppa*,J.M.Davis,E.A.Murphy,andJ.A.Carson+.Quercetin supplementationattenuatestheprogressionofcancercachexiaviaIL-6/STAT3signalingpathway.JNutrition 144(6):868-752014.PMCID:PMC4018949-Impactfactor4.693(5yr) 73.Hardee,J.P.*,C.Porter,L.S.Sidosis,J.A.Carson,D.N.Herndon,andO.E.Suman.Theroleofearlyrehabilitative exercisetrainingintherecoveryfrompediatricburn.MedSci.SportsExercise46(9):1710-62014.PMCID:PMC4122649 -impactfactor4.47(5yr) 72.Puppa,M.J.*,E.A.Murphy,RFayad,G.A.Hand,andJ.A.Carson+.CachecticSkeletalMuscleResponsetoaNovel BoutofLowFrequencyStimulation.JAppl.Physiol.116(8):1078-872014.PMCID:PMC4035786-impactfactor4.14(5yr) 71.Washington,T.A*,J.M.Healey*,R.W.Thompson*,L.L.Lowe,andJ.A.Carson+.Lactatedehydrogenaseregulation inagedskeletalmuscle:Regulationbyanabolicsteroidsandfunctionaloverload.ExperimentalGerontology57:66-74 2014.impactfactor3.80(5yr) 70.J.L.Steiner*,J.M.Davis,J.L.McClellan*,R.T.Enos,J.A.Carson,R.Fayad,M.Nagarkatti,P.S.Nagarkatti,D. Altomare,K.E.Creek,E.A.Murphy:Dose-dependentbenefitsofquercetinontumorigenesisintheC3(1)/SV40Tag transgenicmousemodelofbreastcancer.CancerBiolTher.2014Nov2;15(11):1456-67-impactfactor3.33(5yr) 69.Hardee,J.P.*,Puppa,M.J.*,D.K.Fix*,S.Gao*,K.L.Hetzler*,T.A.Bateman,andJ.A.Carson+.TheEffectof RadiationDoseonMouseSkeletalMuscleRemodeling.Radiation&Oncology48(3):247-562014.PMCID: PMC4110081impactfactor1.60(2012) 68.Gordon,B.S.*,.C.DelgadoDiaz*,J.Carson,R.Fayad,L.B.Wilson,andM.C.Kostek.Resveratrolimprovesmuscle functionbutnotoxidativecapacityinyoungmdxmice.CanadianJ.ofPhysiology&Pharmacology92(3):243-51.2014 -impactfactor1.73(5yr)13Citations 2013 5 67.WhiteJ.P.*,M.J.Puppa.*,GaoS.*,SatoS.*,S.L.WelleandJ.A.Carson+.MusclemTOR1SuppressionbyIL-6During CancerCachexia:AroleforAMPK.AmericanJPhysiol.EndocrineMetab.304(10):E1042-522013.PMCID:3651620 -impactfactor4.83(5yr)24citations 66.Lima,M.*,S.Sato*,R.T.Enos*,J.W.Baynes,andJ.A.Carson+.DevelopmentofanUPLC-massspectrometry methodformeasurementofmyofibrillarproteinsynthesis:applicationtoanalysisofmurinemusclesduringcancer cachexia.JAppliedPhysiol.114(6):824-828,2013PMCID3615602-impactfactor4.14(5yr).7citations 65.White,J.P*.SGao*,M.J.Puppa*,S.Sato*,S.L.Welle,andJ.A.Carson+.Testosteroneregulationof Akt/mTORC1/FOXO3aSignalinginSkeletalMuscle.Molecular&CellularEndocrinology.365(2):174-1862013.PMCID 3529800-impactfactor3.35(5yr)33citations 64.WhiteJ.P.*,M.J.Puppa*,A.A.Narsale*,andJ.A.Carson.CharacterizationofthemaleApcMINmouseasa hypogonadismmodelrelatedtocancercachexia.BiologyOpenDec15;2(12):1346-532013.PMCID:PMC3863419 ImpactFactorTBD 63.Mannie,N.D.P.K.,M.Lima*,R.T.Enos*,P.Wehner,J.A.Carson,andE.Blough.AlteredcardiacmusclemTOR regulationduringtheprogressionofcancercachexiaintheApcMin/+mouse.InternationalJ.Oncology.42(6):213440,2013PMCID23589074-impactfactor2.80(5yr),7citations 2012 62.PuppaM.J.*,J.P.White*,K.T.Velázquez*,K.A.Baltgalvis*,S.Sato*,J.W.Baynes&J.A.Carson+.Theeffect ofexerciseonIL-6inducedcachexiaintheApcMin/+mouse.JCachexiaSarcopenia&Muscle.Jun;3(2):117-37, 2012PMCID:33740192013Impactfactor7.52(5yr.)30citations 61.WhiteJ.P.*,PuppaM.J.*,SatoS.*,GaoS.*,PriceR.L.,BaynesJ.W.,KostekM.C.,MatesicL,andJ.A.Carson+.IL-6 regulationonskeletalmusclemitochondrialremodelingduringcancercachexiaintheApcMin/+mouse.Skeletal Muscle.Jul6:2:14,2012PMCID:3431229ImpactFactor5.14,34citations 60.Frizzell,N.,S.A.Thomas*,J.A.Carson,J.W.Baynes.Mitochondrialstresscausesincreasedsuccinationof proteinsinadipocytesinresponsetoglucotoxixity.BiochemJ.Jul15;445(2):247-54,2012–impactfactor4.66(5yr.) 59.McClellanJ.L.*,J.M.Davis,J.L.Steiner*,DJung*,M.D.Carmichael,J.A.Carson,M.M.Pena,F.G.BergerandE. A.Murphy.Linkingtumorassociatedmacrophages,inflammation,andintestinaltumorigenesis:RoleofMCP-1.AmJ PhysiolGI.15:303(10):G1087-952012-impactfactor3.62(5yr.),21Citations 58.Gordon.B,J.P.White*,J.A.Carson,andM.C.Kostek.Six1andSix1cofactorexpressionisalteredduring earlyskeletalmuscleoverloadinmice"J.PhysiologicalSciences.Sep:62(5):393-401,2012–Impactfactor1.64(5yr)5 citations 2011 57.White,J.P.*,JohnW.Baynes,StephenL.Welle,SuichiSato*,andJ.A.Carson+.Theregulationofskeletal muscleproteinturnoverduringtheprogressionofcancercachexiaintheApcMin/+Mouse.PLosONEvolume6: issue9e246502011PMCID:317627757citations 56.PuppaM.J.*,J.P.White*,S.Sato*,M.Cairns*,J.W.Baynes&J.A.Carson+.Gutbarrierdysfunctioninthe ApcMin/+mousemodelofcoloncancercachexia.Roleofgutbarrierdysfunction.BiochemicaBiophysicaActa: MolecularBasisforDisease.Dec;1812(12):1601-62011.PMCID:320524236citations 55.Washington,T.A.*,J.P.White*,J.M.Davis,†L.B.Wilson,L.L.Lowe,&J.A.Carson+.SkeletalMuscleMass RecoveryfromAtrophyinIL-6-/-Mice.ActaPhysiologica(Oxf)Aug:202(4):657-69,2011PMCID:PMC3129379 42citations 54.White,J.P.*,K.A.Baltgalvis*,M.Puppa*,S.Sato*,J.W.Baynes,andJ.A.Carson+.Muscleoxidativecapacityduring IL-6dependentcancercachexia.AmJPhysiolRegulIntegrCompPhysiol.300:R201-R211,2011.PMCID:PMC3043802 55citations 2010&Earlier 53.Baltglavis,K.A.*,F.GBerger,MM.OPena,J.M.Davis,J.P.White*,andJ.A.Carson*.Activitylevel,apoptosisand thedevelopmentofcachexiainApcMin/+mice.J.AppliedPhysiol.109(4):1155-612010PMCID:PMC29633227citations 52.Carmichael,M.D.,J.M.Davis,E.A.Murphy,J.A.Carson,N.VanRooijen,E.Mayer,andA.Ghaffar.Roleof brainmacrophagesonIL-1betaandfatiguefollowingeccentricexercise-inducedmuscledamage.BrainBehav Immun.24(4):564-8,2010.30citations 6 51.Liu,Huijie,S.E.Chen,B.Jin,J.A.Carson,A.Niu,W.Durham,J.Y.Lai,andY.P.Li.TIMP:3:Aphysiologicalmediatorof adultmyogenensis.J.CellScience123:2914-21,2010.PMCID:PMC292356938citations 50.Baltgalvis,K.A.*,FGBerger,MMOPena,JMDavis,andJACarson+.TheInteractionofaHigh-FatDietand RegularModerateIntensityExerciseonIntestinalPolypDevelopmentinApcMin/+Mice.CancerPrevention Research.Jul:2(7):641-9,2009.PMCID:PMC288650534citations 49.White,J.P.*,K.A.Baltgalvis*,SSato*,LBrittWilson,andJ.A.Carson+.TheEffectofNandroloneDecanoate AdministrationonRecoveryfromBupivacaine-inducedMuscleInjury.JournalofAppliedPhysiology107:14201430,2009.PMCID:PMC277780336citations 48.White,J.P*,J.M.Reecy,T.A.Washington*,S.Sato*,J.MDavis,L.BWilson,andJ.A.Carson+.OverloadinducesskeletalmuscleexracellularmatrixremodelingandmyofiregrowthinmicelackingIL-6.Acta Physiologica197:321-332,2009.PMCID:PMC304443318citations 47.Frizzell,N,MRajesh,MJJepson,RNagai,JACarson,SRThorpe,andJWBaynes.Succinationofthiolgroupsin adiposetissueproteinsindiabetes:Succinationinhibitspolymerizationandsecretionofadiponectin.Journalof BiologicalChemistry284(38):25772-257812009.PMCID:PMC275797955citations 46.BandstraE.R,R.W.Thompson,*G.A.Nelson,S.Judex,M.A.Cairns,*E.R.Benton,J.S.Willey,M.E.Vazquez, J.A.Carson,andTedA.Bateman.MusculoskeletalChangesinMicefrom20–50cGyofSimulatedGalacticCosmic Rays.RadiationResearch.172,21-392009.21citations 45.Baltgalvis,K.A.*,FGBerger,MMOPena,JMDavis,JPWhite*,andJACarson+.Musclewastingand Interleukin-6-inducedatrogin-IexpressionIinthecachecticAPCMin/+mouse.PflugersArch(EuroJPhysiol). Mar;457(5):989-1001.2009PMCID:PMC286711043citations $ 44.BaltgalvisKA*,FGBerger,MMOPena,JMDavis,SJMuga,andJACarson+.Interleukin-6andCachexiain ApcMin/+Mice.AmJ.Physiol.RegulIntegrCompPhysiol294(2):R393-401,2008.124citations 43.BaltgalvisKA*,F.G.Berger,M.M.Pena,J.M.Davis,J.MMcClung*,andJ.A.Carson+.Theeffectofexerciseon biologicalpathwaysinApcMin/+mouseintestinalpolyps.J.Appl.Physiol.104(4):1137-1143,2008.32citations 42.Murphy,E.A.,J.M.,A.S.Brown,M.D.Carmichael,J.A.Carson,vanRooijenN.,A.Ghaffar,andE.P.Mayer. Benefitsofoat(beta)-glucanonrespiratoryinfectionfollowingexercisestress:roleoflungmacrophages.AmJ PhysiolIntegr.CompPhysiol.294(5):R1593-9,2008.29citations 41.McClungJ.*,J.M.Davis,andJ.A.Carson+.OvarianHormoneStatusandSkeletalMuscleInflammationduring RecoveryfromDisuse.ExperimentalPhysiology,92.1219-232,2007.31citations 40.BrownAS,J.M.Davis,E.A.Murphy,M.D.Carmichael,J.A.Carson,A.Ghaffar,andE.PMayer.Susceptibilityto HSV-1infectionandexercisestressinfemalemice:roleofestrogen.JApplPhysiol.Nov;103(5):1592-72007. 9citations 39.Stanfel,M.N,K.A.Moses,J.A.Carson,D.B.Zimmer,F.DeMayo,R.J.Schwartz,andW.E.Zimmer.Expression ofanNkx3.11-CREgeneusingROSAA26reportermice.Genesis44(11):550-5,2006.10citations 38.Carmichael,M.D.,J.M.Davis,E.A.Murphy,J.A.Carson,E.Mayer,andA.Gahaffar.RoleofbrainIL-1Bonfatigue followingexercise-inducedmuscledamage.AmJ.Physiol.RegulIntegrCompPhysiol291:R1344-R1348,2006. 61citations 37.ThompsonR.W.*,JosephM.McClung*,KristenA.Baltgalvis*,J.MarkDavis,andJamesA.Carson+, ModulationofOverload-InducedInflammationbyAgingandAnabolicSteroidAdministration.Experimental Gerontology41:1136-1148,2006.34citations 36.McClungJ.*,J.M.Davis,M.E.Wilson,E.C.Goldsmith,andJ.A.Carson+.Estrogenstatusandskeletalmuscle recoveryfromdisuseatrophy.JournalofAppliedPhysiol.100(6):2012-232006.65citations 35.Brown,A.S.,J.M.Davis+,E.A.Murphy,M.D.Carmichael,J.A.Carson,A.Ghaffar,andE.P.Mayer.Gender differencesinmacrophageantiviralfunctionfollowingexercisestress.Med.Sci.SportsExerc.38(5):859-863,2006.13 citations 34.Alderson,N.L.,W.Yuping,M.Blatnik,N.Frizzell,M.D.Walla,T.J.Lyons,N.Alt,J.A.Carson,R.Nagai,S.R.Thorpe, andJ.W.Baynes+.S-(2-succinyl)cysteine:anovelchemicalmodificationoftissueproteinsbyaKrebscycle intermediate.ArchBiochemBiophys450(1):1-8,2006.35citations 7 33.Mehl,K.A*.,J.M.Davis,F.G.Berger,andJ.A.Carson+.MyofiberDegeneration/Regenerationisinducedinthe cachecticApcMIN/+mouse.JournalofAppliedPhysiol.99:2379-23872005.40citations 32.Mehl,K.A*.,J.M.Davis,J.M.Clements*,F.G.Berger,M.Pena,andJ.A.Carson+.Decreasedintestinalpolyp multiplicitywithexerciseisdependentonintensity,gender,andinflammatorystateinApcMIN/+mice.Journalof AppliedPhysiology98:2219-2225,2005.61citations 31.McClungJ.*,K.Mehl*,R.W.Thompson*,L.L.Lowe,andJ.A.Carson+.NandroloneDecanoatemodulatesinitial overloadinducedchangesinmusclemorphologyandgeneexpressioninratsoleusmuscle.AmJPhysiolRegulIntegr CompPhysiol.288:R1543-R1552,2005.28citations 30.Carmichael,M.D.*,J.M.Davis+,E.A.Murphy*,A.S.Brown*,J.A.Carson,E.Mayer,andA.Ghaffar.Recoveryof runningperformancefollowingmuscledamagingexercise:RelationshiptobrainIL-1β.Brain,Behavior,&Immunity, 19(5):445-52,2005.40citations $ 29.Neiman,D.C.,J.M.Davis,D.A.Henson,S.J.Gross,C.L.Dumke,A.C.Utter,D.M.Vinci,J.A.Carson,A.Brown*,SR McAnulty,LSMcAnulty,andNTTriplett.MusclecytokinemRNAchangesafter2.5hofcycling:influenceof carbohydrate.MedSciSportsExerc.37(8):1283-90,2005.100citations 28.Washington,T.A.*,J.M.Reecy,R.W.Thompson*,L.L.Lowe,J.M.McClung*,andJ.A.Carson+.Lactate DehydrogenaseExpressionattheOnsetofAlteredLoadinginRatSoleusMuscle.J.Appl.Physiol.97:1424-1430,2004. 15citations 27.AltN.*,J.A.Carson,N.L.Alderson,R.Nagai,T.Henle,S.R.Thorpe,andJ.W.Baynes+.Muscleproteinisprotected fromchemicalmodificationindiabeticrats.ArchivBiochem&Biophys425:200-206,2004.53citations 26.McClungJ.*,R.W.Thompson*,L.L.Lowe,andJ.A.Carson+.RhoAexpressionduringrecoveryfromskeletalmuscle disuse.J.Appl.Physiol.Apr;96(4):1341-8,2004.19citations $ 25.Neiman,D.C.,J.M.Davis,V.A.Brown,D.A.Henson,C.L.Dumke,A.C.Utter,D.M.Vinci,M.F.Downs,J.C.Smith, J.A.Carson,A.Brown*,S.R.McAnultyandL.S.McAnulty.Carbohydrateandimmunityfollowingresistancetraining. J.Appl.Physiol.Apr;96(4):1292-8,2004.156citations 24.Carson,J.A.+,D.E.Culberson,R.W.Thompson*,R.A.Fillmore,andW.E.Zimmer.Smoothmuscleγ-actinpromoter regulationbyRhoAandserumresponsefactorsignaling.BiochimicaetBiophysicaActa,Jul28;1628(2):133-9,2003. 8 citations 23.McClung,J.*,W.J.Lee*,R.W.Thompson*,L.L.Lowe,andJ.A.Carson+.RhoAinductionbyfunctionaloverloadand nandrolonedecanoateadministrationinratskeletalmuscle.EuropeanJ.Physiol.;PflugersArchiv.Dec;447(3):345-55, 2003.25citations 22.Lee,W.J.*,J.McClung*,R.W.Thompson*,andJ.A.Carson+.RegulationofAndrogenReceptorExpressionatthe onsetoffunctionaloverloadinratplantarismuscle.AMJPhysiolRegulIntegrCompPhysiol.Nov;285(5):R1076-85. 2003.42citations 21.Lee,W.J.*,J.McClung*,G.A.Hand,andJ.A.Carson+.Overload-inducedandrogenreceptorexpressionintheaged rathindlimbreceivingnandrolonedecanoate.J.Appl.Physiol.94:1153-1161,2003.41citations 20.McClung,J.*,G.Hand,J.M.Davis,andJ.A.Carson+.Effectofcreatinesupplementationonthecardiacmuscleof endurancetrainedrats.Euro.J.Appl.Physiol.89:26-332003.10citations $ 19.Nieman,D.C.,J.M.Davis,D.A.Henson,J.Walberg-Rankin,M.Shute,C.L.Dumke,A.C.Utter,D.M.Vinci,J.A.Carson, A.Brown*,W.J.Lee*,S.R.McAnulty,andL.S.McAnulty.Carbohydrateingestioninfluencesskeletalmusclecytokine mRNAandplasmacytokinelevelsaftera3-hrun.J.Appl.Physiol.94:1917-1925,2003.273citations 18.Carson,J.A.+,W.J.Lee*,J.McClung*,andG.A.Hand.SteroidReceptorConcentrationinagedrathindlimbmuscle:The effectofanabolicsteroidadministration.J.Appl.Physiol.93:242-250,2002.51citations 17.Hand,G,C.Hewitt,L.Fulk,*H.Stock,J.A.Carson,J.Davis,andM.Wilson.Differentialreleaseofcorticotropin-releasing hormone(CRH)intheamygdaladuringdifferenttypesofstretch.BrainResearch949:122-130,2002.43citations $ 16.Carson,JA,D.Nettleton,andJ.M.Reecy.Differentialgeneexpressionintheratsoleusmuscleduringearlywork overload-inducedhypertrophy.FASEBJ16(2):207-209,2002.115citations 8 15.Wei,L.,L.Wang,J.A.Carson,J.E.Agan,K.I.Yoshida,andR.J.Schwartz.β1integrinandorganizedactinfilaments facilitatescardiomyocytespecificRhoA-dependentactivationoftheskeletalα-actinpromoter.FASEBJ.15:785-7962001. 65citations $ 14.Carson,J.A.,R.A.Fillmore,R.J.Schwartz,andW.E.Zimmer.Thesmoothmusclegamma-actingenepromoterisa moleculartargetformNkx3.-1,avertebratehomologueofDrosophilaBagpipe,andserumresponsefactor.J.Biol. Chem.275(50):39061-39072,2000.100citations $ 13.Fluck,M.,J.A.Carson,A.Ziemieki,andF.W.Booth.FocaladhesionproteinsFAKandpaxillinincreasewithoverloadinducedhypertrophyofALDmuscle.AmJ.Physiol.277(46):C152-C162,1999.111citations 12.Fluck,Martin,J.A.Carson,R.J.Schwartz,andF.W.Booth.SRFproteinisup-regulatedduringstretch-induced hypertrophyofroosterALDmuscle.J.Appl.Physiol.86(6):1793-1799,1999.50citations 11.Carson,J.A.,andF.W.Booth.SerumresponsefactormRNAinductioninthe hypertrophyingchickenpatagialismuscle.J.Appl.Physiol.86(1):377-3821999.16citations 10.Carson,J.A.,andF.W.Booth.Effectofserumandmechanicalstretchonskeletalα-actingeneregulationincultured primarymyocytes.Am.J.Physiol.(CellPhysiol.44):C1438-1448,1998.45citations 9.Carson,J.A.,andF.W.Booth.MyogeninmRNAiselevatedduringrapid-,slow-,andmaintenance-phasesofstretchinducedhypertrophy.PflugersArch-Eur.J.Physiol.435:850-858,1998.45citations 8.Marsh,D.R.,J.A.Carson,L.N.Stewart,andF.W.Booth.Activationoftheskeletalα-actinpromoterduringmuscle regeneration.J.MuscleRes.&CellMot.19(8):897-907,1998.18citations $ 7.Marsh,D.R.,D.S.Criswell,J.A.Carson,W.T.Lester,andF.W.Booth.Myogenicregulatoryfactorsduringregeneration ofskeletalmuscleinyoung,adult,andoldrats.J.Appl.Physiol.83(4):1270-1275,1997.137citations 6.Carson,J.A.,R.J.SchwartzandF.W.Booth.SRFandTEF-1regulationoftheskeletalα-actinpromoterduringstretch overloadinducedhypertrophyinslowtonicmuscleofyoungchickens.Am.J.Physiol.(Cell39)270:C1624-C1633,1996. 89citations 5.Carson,J.A.,andS.E.Alway.Stretchoverload-inducedsatellitecellactivationinslowtonicmusclefromadultand agedJapanesequail.Am.J.Physiol.(Cell39)270:C578-C584,1996.51citations 4.Carson,J.A.,M.YamaguchiandS.E.Alway.Thetimecourseofadaptationstostretch-overloadintheagedJapanese quail.J.Gerontology50(6):B391-398,1995.20citations 3.Carson,J.A.,Z.Yan,F.W.Booth,M.E.Coleman,R.J.Schwartz,andC.S.Stump.Regulationoftheskeletalα-actin promoterinyoungchickensduringhypertrophycausedbystretchoverload.Am.J.Physiol.(Cell37):C918-C924,1995. 61citations 2.Alway,S.E.,J.A.CarsonandW.J.Roman.Adaptationinmyosinexpressionofavianskeletalmuscleafterweighting andunweighting.J.MuscleRes.&CellMot.16:111-122,1995.9citations 1.Carson,J.A.,M.Yamaguchi.andS.E.Alway.Hypertrophyandproliferationofskeletalmusclefibersfromagedquail. J.Appl.Physiol.78(1):293-299,.1995.36citations 9 Scholarship:RefereedLiteratureReviews/BookChapters *denotesUSCmentoredstudentauthorcontribution(italicsdirectJ.Carsonsupervision) +denotescorrespondingauthor/seniorauthor $ BOLDreference:highlycitedarticle(over100citations) RefereedReviewofLiteraturePublications 10.Carson,J.A.+,J.P.Hardee*,&B.N.VanderVeen*.Skeletalmuscleoxidativemetabolism’semergingroleasa biologicaltargetandcellularregulatorofcancer–inducedmusclewasting.Seminars–CellandDev.Biol.Inpress 2015.(invitedrefereed)impactfactor–6.21(5yr). 9.Carson,J.A.&S.C.Manolagas.Effectsofsexsteroidsonbonesandmuscles:similarities,parallels,and putativeinteractionsinhealthanddisease.BoneNov;80:67-78.2015PMCID:PMC4600533(invited,refereed) impactfactor4.31(5yr). 8.NarsaleAA*,&J.A.Carson+.Roleofinterleukin-6incachexia:therapeuticimplications.CurrOpinSupport PalliatCare.2014Dec;8(4):321-7.PMCID:PMC4323347(invited,refereed)2014impactfactor1.66 7.CarsonJ.A.+&K.Baltgalvis*.Interleukin6asakeyregulatorofmusclemasswithcancercachexia.Exercise& SportsScienceReviews,38:4168-176,October2010.(invited,refereed)2014impactfactor4.82PMCID:PMC3065300 85citations 6.Dudgeon,W.D.*,PhillipsK.D.,CarsonJ.A.,BrewerR.B.,DurstineJ.L.,andG.A.Hand+:Counteracting musclewastinginHIV-infectedindividuals.HIVMedicine(7):299-310,2006.68citations 5.A.Pinasco*&J.A.Carson+.Preseasonconditioningforcollegesoccerplayers.StrengthandConditioning Journal,NationalStrength&ConditioningAssociation27(5):56-65,2005. $ 4. Carson,J.A.+,andL.Wei.IntegrinSignalling:Apotentialroleinoverload-inducedhypertrophy.J.Appl. Physiol.88:337-343,2000.(invited,refereed)130citations $ 3.Booth,F.W.,B.S.Tseng,M.Fluck,andJ.A.Carson.Molecularandcellularadaptationofmuscleinresponse tophysicaltraining.ActaPhysiol.Scand.162:343-350,1998.126citations 2.Carson,J.A.+.TheregulationofGeneExpressioninHypertrophyingSkeletalMuscle.(ed)J.O.Holloszy. ExerciseandSportsScienceReviews.Balt.MD.Williams&Wilkins.pg301-320,1997.(invited,refereed)45 citations 1.Criswell,D.S.,J.A.Carson,andF.W.Booth.Regulationofcontractileproteingeneexpressioninunloaded mouseskeletalmuscle.J.GravitationalPhysiol.3(2):58-60,1996.5citations BookChapters J.A.Carson&M.Puppa*.BiologicalPathwaysImpactingCancerSurvival:Exerciseasacountermeasureforthe developmentandprogressionofcachexia.(eds)C.Ulrich,KSteindorf,NBerger.Exercise,EnergyBalanceandCancer. Series:EnergyBalanceandCancer2012 J.Baynes&J.ACarson.Muscle:EnergyMetabolismandContraction.(ed)J.Baynes&M.H.Dominiczak.Medical Biochemistry,Mosby2009. J.Baynes&J.ACarson.Muscle:EnergyMetabolismandContraction.(ed)J.Baynes&M.H.Dominiczak.Medical Biochemistry,Mosby2004. Carson,J.A.,andF.W.Booth.Molecularbiologyofexercise.(ed)W.E.Garrett.Textbook Media,PA.Williams&Wilkins.2000.1citation ofSportsMedicine(Vol.I). BoothF.W.,J.A.CarsonandZ..Yan.Molecularandcellularadaptationsofmuscle inresponsetoexercise.(eds)R.J. MaughanandS.M.Shirreffs.BiochemistryofExerciseIX.Champaign,IL.HumanKinetics.pg339-344,1996 10 Scholarship:Presented/PublishedAbstracts 2016 SongGaoandJA.Carson.BasalandStretch-inducedMyotubeProteinSynthesisRegulationbygp130Signaling.Advancesin SkeletalMuscleBiologyinHealthandDiseaseConference,Gainesville,FL,2016. JPHardee,SGao,DKFix,BNVanderVeen,KLHetzler,andJACarson.Cachecticmouseskeletalmuscleanabolicresponseto acuteandtrainingeccentriccontractions.AdvancesinSkeletalMuscleBiologyinHealthandDiseaseConference, Gainesville,FL,2016. DennisK.Fix,JustinP.Hardee,SongGao,KimbellL.Hetzler,JA.Carson.TheRoleofgp130intheRegulationofMuscle MitochondrialDynamicswithCancerCachexia.CenterforColonCancerResearchRetreat,Columbia,SC,2016. 2015 HardeeJP,GaoS,FixDK,VanderVeenBN,HetzlerKL,andJACarson.Cachecticmouseskeletalmuscleanabolicresponsetoacuteand th trainingeccentriccontractions.8 InternationalConferenceonCachexia,SarcopeniaandMuscleWasting.Paris,France. December2015. HardeeJP,MangumJE,FixDK,SatoS,PuppaMJ,HetzlerKL,andJACarson.Cachecticskeletalmuscleresponsetoeccentricand concentriccontractions.ACSMNationalMeeting,SanDiegoCA.May2015 GaoS,andCarsonJA.LewisLungCarcinomaRegulationofMechanicalStretch–InducedProteinSynthesisinCultured Myotubes.ExperimentalBiology,April2015.Boston,MA. LABrown,JLBrown,MERosa,DELee,RAPerryJr,JPHardee,JACarson,NPGreeneandTAWashington.ProgressionofCancerCachexia AltersMuscleLactateMetabolisminApcMin/+Mice.ExperimentalBiology,April2015.BostonMA HetzlerKL,HardeeJP,PuppaMJ,NarsaleAA,SatoS,DavisJM,CarsonJA.IL-6Signalingduringcancercachexiaprogression:Thefemale responseExperimentalBiology,April2015.BostonMA 29(1Supplement):1038.11 HardeeJP,GaoS,HetzlerKL,SatoS,PuppaMJ,andCarsonJA.Stat3regulationincachecticskeletalmuscleafterrepeatedeccentric contractions.ExperimentalBiology,April2015.BostonMA HardeeJP,MangumJE,FixDK,SatoS,PuppaMJ,HetzlerKL,andCarsonJA.Cachecticskeletalmuscleresponsetoeccentricand concentriccontractions:aroleforstat3signaling.AmericanCollegeofSportsMedicineConference,SoutheastChapter, February2015.JacksonvilleFL 2014 HetzlerKL,CarsonJA.Effectsofovarianfunctiononcancercachexiaprogression.UniversityofSouthCarolinaWomen'sHealthResearch Forum,October2014. Puppa,MJ.,Narsale,AA.,Carson,JA.,RoleofIL-6Trans-SignalingonMuscleProteinSynthesisDuringCancerInducedCachexia. ExperimentalBiology,Apr,2014,SanDiego,CA. HardeeJP,PorterC,SidossisLS,CarsonJA,HerndonDN,andSumanOE.EffectofEarlyandLateOutpatientExerciseTrainingonMuscle MassandProteinKineticsinSeverelyBurnedChildren.ExperimentalBiology.April2014.SanDiego,CA. Narsale,AA.,EnosR.,Puppa,MJ.,Carson,JA.,LiverProteinSynthesisandGlycogenStoragewiththeProgressionofCancerCachexia, ExperimentalBiology,Apr,2014,SanDiego,CA. GaoS,andCarsonJA.Lewislungcarcinomacellsregulationofstretch-inducedmTORactivationinC2C12myotubes.Experimental Biology.April2014.SanDiego,CA. HetzlerKL,SatoS,NarsaleAA,PuppaMJ,CarsonJA.TheEffectofSexonIL-6RegulationofCancerCachexiaProgressionintheApcmin/+ mouse.ExperimentalBiology.April2014.SanDiego,CA. MangumJE,HardeeJP,PuppaMJ,CarsonJA.TheEffectofCachecticMyofiberMetabolicPropertiesontheResistanceExercise-Induced HypertrophyResponse.ExperimentalBiology.April2014.SanDiego,CA. HetzlerKL,CarsonJA.SexDifferencesinResponsetoIL-6duringtheProgressionofCancerCachexia.UniversityofSouthCarolina GraduateStudentDay.April2014.Columbia,SC. AugustineMR,HardeeJP,BatemanTA,andCarsonJA.TheEffectofUnloadingandIrradiationonSkeletalMuscleProteinTurnover. USCDiscoveryDay.April2014.Columbia,SC. LearnerEL,PuppaMJ,HardeeJP,HetzlerKL,andCarsonJA.Theroleoftheskeletalmusclegp130receptorinIL-6inducedmuscle morphologicalchanges.DiscoveryDay.April2014.Columbia,SC. Durante,E.,Narsale,AA.,Carson,JA.,TheEffectofAntibioticTreatmentonLiverFunctionintheApcMin/+mousemodelofCancer Cachexia,DiscoveryDay,April2014,Columbia,SC SimmonsM.,Narsale,AA,CarsonJA,RoleofIL-6SignalingonSkeletalMuscleWastingintheFemaleLewisLungCarcinomaModelof Cachexia,DiscoveryDay,Apr.2014,Columbia,SC. HardeeJP,PorterC,SidossisLS,CarsonJA,HerndonDN,andSumanOE.Effectofearlyoutpatientexercisetrainingonskeletalmuscle massandfunctioninseverelyburnedchildren.AmericanBurnAssoc.March2014.Boston,MA. 2013 YangJH,NarsaleAA,Aartun,JDPuppa,MJ,and,CarsonJA.TheEffectofAntibiotictreatmentonLiverfunctionduringCancerCachexia. CollegeofEngineeringandComputing,USouthCarolinaandSCGovernor’sSchoolforScienceandMathematics,Columbia SCJuly2013 SchreinerM.,PuppaM,NarsaleA,McClellanJ,ReaganL,CarsonJ.Theeffectofleptinreceptorantagonistadministrationonratskeletal musclemetabolicgeneregulation.USouthCarolinaandSCGovernor’sSchoolforScienceandMathematics,ColumbiaSCJuly 2013. 11 HardeeJP,PuppaMJ,NarsaleAA,GaoS,andCarsonJA.TheEffectofCachexiaSeverityandResistanceExerciseonSkeletalMuscle Mass.AmericanCollegeofSportsMedicine.May2013.Indianapolis,IN. M.J.Puppa,J.A.Carson.Cachecticskeletalmuscleresponsetoanovelboutoflowfrequencystimulation.AmericanCollegeofSports Medicine.May2013.Indianapolis,IN. PuppaMJ,NarsaleAN,GaoS,CarsonJA.Skeletalmusclegp130receptorregulationofcancercachexia-inducedmusclemassloss. ExperimentalBiology.April2013Boston,MA. GaoS,CarsonJA.RoleofTrans-signalingMoleculesfromLewisLungCarcinoma(LLC)CellsonC2C12MyotubeAtrophyandProtein TurnoverRegulation.ExperimentalBiology.April2013Boston,MA. PuppaMJ,NarsaleAN,GaoS,CarsonJA.Skeletalmusclegp130receptorregulationofcancercachexia-inducedmusclemassloss.St.Jude NationalGraduateStudentSymposium.March2013Memphis,TN. PuppaM.J.,andJ.A.Carson.Cachecticskeletalmuscleresponsetoanovelboutoflowfrequencystimulation.AmericanCollegeofSports MedicineConference,SoutheastChapter.GreenvilleSCFeb2013. HardeeJP,PuppaMJ,NarsaleAA,GaoS,andCarsonJA.TheEffectofCachexiaSeverityandResistanceExerciseonSkeletalMuscleMass AmericanCollegeofSportsMedicineConference,SoutheastChapter.GreenvilleSCFeb2013. EngelA.,VelazquezK.,NarsaleA.,PuppaM.J.,J.A.Carson.Theeffectofil-6lossoninitialladderclimbingexercise-inducedchangesin strengthandmusclemass.AmericanCollegeofSportsMedicineConference,SoutheastChapter.GreenvilleSCFeb2013. 2012 HardeeJP,PuppaMJ,SatoS,CarsonWO,HetzlerKL,BatemanT,andJ.A.Carson.TheEffectofRadiationDosingonMouseSkeletal MuscleOxidativeMetabolism.AmericanSocietyforGravitational&Space.NewOrleans,November2012 Sato,S.,M.J.Puppa,S.Gao,andJ.A.Carson.TheeffectofmusclecontractiononcachecticmusclemTORsignalingandproteinsynthesis Min/+ inApc mouse.AmericanPhysiologicalSociet/IntegrativePhysiologyofExerciseMeeting,DenverCO,October2012. PuppaM.J,J.P.White,S.Sato,S.Gao,andJ.A.Carson.TheeffectofexercisetrainingonanabolicresponsesinIL-6-inducedcancer cachexia.CancerCachexiaConferenceMolecularMechanismsandTherapeuticApproaches.BostonSeptember2012. CarsonWO,HardeeJPandCarsonJA.Theeffectofradiationdosageonmouseskeletalmuscleoxidativecapacity.CollegeofEngineering andComputing,UniversityofSouthCarolinaandSCGovernor’sSchoolforScienceandMathematics,ColumbiaSCJuly2012. WhiteC.,PuppaM.J.,McClellanJ.,andJ.A.Carson.Theeffectsofquercetinonskeletalmuscleproteindegradationandoxidative capacityinmiceafflictedwithchemicallyinducedcancercachexia.SummerProgramsforResearchInterns.Collegeof EngineeringandComputing,UniversityofSouthCarolinaandSCGovernor’sSchoolforScienceandMathematics,ColumbiaSC July2012. PuppaM.J.,J.P.White,S.Sato,andJ.A.CarsonIL-6signalingregulatesmuscleFIS1expressionduringtheprogressionofcachexia. AdvancesinSkeletalMuscleBiologyinHealth&DiseaseConference.Feb2012 SatoS.,M.J.Puppa,A.A.Narsale,A.D.Johannes,andJ.A.Carson.Theeffectofresistancetrainingonmusclemaintenanceinthe ApcMin/+mice.AdvancesinSkeletalMuscleBiologyinHealthandDisease,Gainsville,Florida.Feb2012 GaoS.,andJ.A.Carson.EffectsofdifferentdosesofIL-6onpathwaysregulatingproteinturnoverinC2C12myotubes.Advancesin SkeletalMuscleBiologyinHealthandDisease,Gainsville,Florida.Feb2012 PuppaM.J.,J.P.White,K.T.Velazquez,S.Sato,A.ANarsale,andJ.A.Carson.EffectofexercisetrainingonmuscleenergystatusinIL-6 inducedcachexia.AmericanCollegeofSportsMedicineConference,SoutheastChapter.Jacksonville,FL.Feb2012. VelazquezK.T.,J.P.Hardee,M.J.Puppa,J.D.Aartun,A.A.Narsale,S.Sato,J.M.Davis,andJ.A.Carson.TheEffectofQuercentin SupplementationonVolitionalFatigueandSkeletalMuscleMassRetentionDuringCancerCachexia.AmericanCollegeofSports MedicineConference,SoutheastChapter.Jacksonville,FL.Feb2012. 2011 VelazquezK.T.,R.T.Enos,A.Narsale,JAartun,M.J.Puppa,E.A.Murphy,M.J.Davis,J.A.Carson.Curcuminandquercetin supplementationattenuateleanbodymasslossduringtheprogressionofcancercachexiaintheLewisLungCarcinoma-tumorMin/+ bearingmouseandApc mouse.6thCachexiaConference.Milan,Italy.Dec2011. White,JP.,Sato,S,Puppa,M,CarsonJ.ExercisetrainingpreventsIL-6suppressionofmusclePGC-1αandMitofusin1&2proteinsduring theprogressionofcachexiaintheApcMin/+mouse.AmericanInstituteforCancerResearchAnnualResearchConference, WashingtonDC(November2011). SatoS.,M.J.Puppa,K.T.Velazquez,A.Narsale,J.P.WhiteandJ.A.Carson.TheEffectOfTumorGrowthAndModerateExerciseOn ApcMin/+MouseCageActivity.NationalAmericanCollegeofSportsMedicineMeeting.Denver,CO.June2011. PuppaM.J.,JWhite,KVelazquez,SSato,JAartun,J.A.Carson,Effectofexercisetrainingonneuromuscularperformanceincachectic mice.NationalAmericanCollegeofSportsMedicineMeeting.Denver,CO.June2011. SatoS.,M.Lima,R.Enos,J.W.BaynesandJ.A.Carson.Theeffectofoxidativecapacityonmousemuscleproteinsynthesisduring cachexia.ExperimentalBiology,Washington,D.C.April2011. WhiteJ.P,,MPuppa,SSato,JBaynes,J.A,Carson.IL-6inhibitionattenuatesactivationofubiquitinproteasome-dependentdegradation incachecticmuscle.ExperimentalBiology,Washington,D.C.April2011. NarsaleA.A,JD.Aartun,MJ.Puppa,SSato,JP.White,JW.Baynesand,J.A.Carson;Theroleofgutpermeabilityandsystemic Min/+ bacterialloadoncachexiaprogressioninApc mice.GraduateStudentDay,8thApril,2011. PuppaM.J.,J.P.White,K.Velazquez,S.Sato,J.Aartun,J.A.Carson,Effectofexercisetrainingonneuromuscularperformancein cachecticmice.SoutheastRegionAmericanCollegeofSportsMedicineMeeting,GreenvilleSC.Feb2011 2010 White,J.P.PuppaMJ,Velazquez,KT,BaynesJWandJ.A.Carson.MuscleproteinSynthesisandIL-6-inducedCachexiaintheApcMin/+ Mouse.ACSM’sConferenceonIntegrativePhysiologyofExerciseendorsedbyTheAmericanPhysiologicalSocietyMiami,FL September2010. 12 AndersonS.N.,M.J.Puppa,WhiteJPandJ.A.Carson.Theeffectofexerciseonskeletalmuscleoxidativestressandmitochondrial biogenesisinApcMin/+mice.SummerProgramsforResearchInterns.CollegeofEngineeringandComputing,Universityof SouthCarolinaandSCGovernor’sSchoolforScienceandMathematics,ColumbiaSCJuly2010. Sharperson,C.M.,WhiteJP,PuppaM.,andJ.A.Carson.Theeffectsofexerciseandfishoilsupplementationonthedevelopmentof anemiainacolorectalcancermousemodel.SummerProgramsforResearchInterns.CollegeofEngineeringandComputing, UniversityofSouthCarolinaandSCGovernor’sSchoolforScienceandMathematics,ColumbiaSCJuly2010. Pupa,M.J.,J.P.White,K.TVelazquez,J.W.Baynes,andJ.A.Carson,treadmillexerciseandglucoseclearanceinApcMin/+mice.American CollegeofSportsMedicineNationalMeeting,BaltimoreMD,June2010. White,J.P.PuppaMJ,Velazquez,KT,BaynesJWandJ.A.Carson.TreadmillExerciseandIL-6-inducedCachexiaintheApcMin/+Mouse. AmericanCollegeofSportsMedicine.Baltimore,MDJune2010. WhiteJ.P.,S.Sato,S.L.WelleandJamesA.Carson.TheeffectofcastrationonIGF-1signalingandmetabolicregulationinskeletalmuscle. AmericanFederationforAgingResearchGrenteeMeeting.SantaBarbara,CAJune2010. White,J.P.,ShuichiSato,MelissaJ.Puppa,JohnW.BaynesStephenL.WelleandJamesA.Carson,IL-6-inducedCachexiaandMuscleIGF1Signaling,ExperimentalBiology.Anaheim,CA.April2010 Pupa,M.J.,JamesP.White,MarkA.Cairns,ShuichiSato,JohnW.Baynes,andJamesA.Carson,Roleofgutbarrierdysfunctionand endotoxemiaindevelopmentofcoloncancercachexia,ExperimentalBiology,AnaheimCA,April2010.(2005.2) VelazquezK.T.,SSato,JPWhite,MJPuppa,JWBaynes,andJACarson.SkeletalMuscleOxidativeCapacityinCachecticMice. ExperimentalBiology,AnaheimCA,April2010(283.11/II13) WhiteJ.P.,M.J.Puppa,S.Sato,J.W.BaynesandJ.A.Carson.GlucoseToleranceandExerciseinaMouseModelofCancerCachexia. AmericanCollegeofSportsMedicineConference,SoutheastChapterRegionalMeetingGreenville,SC.February2010. SheehanJ,WhiteJP,ShuichiSatoandJamesCarson,TheAssociationbetweenGlucoseToleranceandCachexiaintheApcMin/+Mouse. AmericanCollegeofSportsMedicine,SoutheastChapter.Greenville,SC.February2010. 2009&earlierover100notshown 13 Scholarship:MentoredHighSchoolResearch InternationalExchangeHighSchoolStudents 2015SouthCarolinaFallProgramforResearchInterns.UniversityofSouthCarolinaHonorsCollege&SouthCarolina Governor’sSchoolforScienceandMath.**Student:LuisHauptmann,JohannaWittumSchuleSchool,Germany, GermanHighSchoolExchangeStudent;Mentor:JamesA.Carson. 2015SouthCarolinaFallProgramforResearchInterns.UniversityofSouthCarolinaHonorsCollege&SouthCarolina Governor’sSchoolforScienceandMath.**Student:NathalieBrucker,JohannaWittumSchuleSchool,Germany, GermanHighSchoolExchangeStudent;Mentor:JamesA.Carson. 2014SouthCarolinaFallProgramforResearchInterns.UniversityofSouthCarolinaHonorsCollege&SouthCarolina Governor’sSchoolforScienceandMath.**Student:HannaMeisi,JohannaWittumSchuleSchool,Germany,German HighSchoolExchangeStudent;Mentor:JamesA.Carson. 2013SouthCarolinaFallProgramforResearchInterns.UniversityofSouthCarolinaHonorsCollege&SouthCarolina Governor’sSchoolforScienceandMath.**Student:InesMazurek,JohannaWittumSchuleSchool,Germany,German HighSchoolExchangeStudent;Mentor:JamesA.Carson. 2013SouthCarolinaSummerProgramforResearchInterns.UniversityofSouthCarolinaHonorsCollege&SouthCarolina Governor’sSchoolforScienceandMath.**Student:JihoonYang,GyeonggiScienceHighSchool,KoreanHighSchool ExchangeStudent;Mentor:JamesA.Carson. 2012SouthCarolinaFallProgramforResearchInterns.UniversityofSouthCarolinaHonorsCollege&SouthCarolina Governor’sSchoolforScienceandMath.**Student:NicoleEger,GermanHighSchoolExchangeStudent;Mentor: JamesA.Carson.Project:AnacuteexerciseboutoncachecticmuscleAMPKandPGC-1α. 2012SouthCarolinaSummerProgramforResearchInterns.UniversityofSouthCarolinaHonorsCollege&SouthCarolina Governor’sSchoolforScienceandMath.**Student:EnjooKang,KoreanHighSchoolExchangeStudent;Mentor:James A.Carson.Project:TheRoleofthegp130ReceptorinCachexia. SouthCarolinaHighSchoolStudents 2015InternationalBaccalaureateProgramProject,DreherHighSchool.Student:JanaLiese,Mentor:JamesA.Carson. 2015SouthCarolinaSummerProgramforResearchInterns.UniversityofSouthCarolinaHonorsCollege&SouthCarolina Governor’sSchoolforScienceandMath.Student:HermaniPatel,SCGovernor’sSchoolforScience&Mathematics; Mentor:JamesA.Carson. 2015SouthCarolinaSummerProgramforResearchInterns.UniversityofSouthCarolinaHonorsCollege&SouthCarolina Governor’sSchoolforScienceandMath.Student:EmiliaBaliou,SCGovernor’sSchoolforScience&Mathematics; Mentor:JamesA.Carson. 2014DutchForkHighSchoolResearchProgram,StudentOliviaReszcynski:MentorJamesCarson, 2014SouthCarolinaSummerProgramforResearchInterns.UniversityofSouthCarolinaHonorsCollege&SouthCarolina Governor’sSchoolforScienceandMath.Student:NathanPigone,SCGovernor’sSchoolforScience&Mathematics; Mentor:JamesA.Carson. 2014SouthCarolinaSummerProgramforResearchInterns.UniversityofSouthCarolinaHonorsCollege&SouthCarolina Governor’sSchoolforScienceandMath.Student:MayankPatel,SCGovernor’sSchoolforScience&Mathematics; Mentor:JamesA.Carson. 2013SouthCarolinaSummerProgramforResearchInterns.UniversityofSouthCarolinaHonorsCollege&SouthCarolina Governor’sSchoolforScienceandMath.Student:JacquelineBudidharma,SCGovernor’sSchoolforScience& Mathematics;Mentor:JamesA.Carson. 2013SouthCarolinaSummerProgramforResearchInterns.UniversityofSouthCarolinaHonorsCollege&SouthCarolina Governor’sSchoolforScienceandMath.Student:MathiasSchreinerSCGovernor’sSchoolforScience&Mathematics; Mentor:JamesA.Carson.Project 2012SouthCarolinaSummerProgramforResearchInterns.UniversityofSouthCarolinaHonorsCollege&SouthCarolina Governor’sSchoolforScienceandMath.Student:CameronWhite,SCGovernor’sSchoolforScience&Mathematics; Mentor:JamesA.Carson. 2012SouthCarolinaSummerProgramforResearchInterns.UniversityofSouthCarolinaHonorsCollege&SouthCarolina Governor’sSchoolforScienceandMath.Student:WilliamCarson,LexingtonHighSchool;Mentor:JamesA.Carson. 14 2011SouthCarolinaSummerProgramforResearchInterns.UniversityofSouthCarolinaHonorsCollege&SouthCarolina Governor’sSchoolforScienceandMath.Student:KyleBrennan,SCGovernor’sSchoolforScience&Mathematics; Mentor:JamesA.Carson. 2011SouthCarolinaSummerProgramforResearchInterns.UniversityofSouthCarolinaHonorsCollege&SouthCarolina Governor’sSchoolforScienceandMath.Student:DanielleSchwartz,SCGovernor’sSchoolforScience&Mathematics; Mentor:JamesA.Carson. 2010–2011DanielMiller,RichlandNortheastHighSchool,MagnateHonorsProgramResearchPaper Researchmentor/communityexpert:JamesCarson 2010SouthCarolinaSummerProgramforResearchInterns.UniversityofSouthCarolinaHonorsCollege&SouthCarolina Governor’sSchoolforScienceandMath.Student:CamaraSharperson,SCGovernor’sSchoolforScience&Mathematics; Mentor:JamesA.Carson. 2010SouthCarolinaSummerProgramforResearchInterns.UniversityofSouthCarolinaHonorsCollege&SouthCarolina Governor’sSchoolforScienceandMath.Student:SamuelAnderson,SCGovernor’sSchoolforScience&Mathematics; Mentor:JamesA.Carson. 2009SouthCarolinaSummerProgramforResearchInterns.UniversityofSouthCarolinaHonorsCollege&South CarolinaGovernor’sSchoolforScienceandMath.Student:GraceBradford,SCGovernor’sSchoolforScience& Mathematics;Mentor:JamesA.Carson. 2009SouthCarolinaSummerProgramforResearchInterns.UniversityofSouthCarolinaHonorsCollege&SouthCarolina Governor’sSchoolforScienceandMath.Student:AlexKabil,SCGovernor’sSchoolforScience&Mathematics;Mentor: JamesA.Carson. 2008SouthCarolinaSummerProgramforResearchInterns.UniversityofSouthCarolinaHonorsCollege&SouthCarolina Governor’sSchoolforScienceandMath.Student:SaraLancaster,SCGovernor’sSchoolforScience&Mathematics; Mentor:JamesA.Carson. 2007SouthCarolinaSummerProgramforResearchInterns.UniversityofSouthCarolinaHonorsCollege&SouthCarolina Governor’sSchoolforScienceandMath.Student:VictorRusso,SCGovernor’sSchoolforScience&Mathematics; Mentor:JamesA.Carson. 2007SouthCarolinaSummerProgramforResearchInterns.UniversityofSouthCarolinaHonorsCollege&SouthCarolina Governor’sSchoolforScienceandMath.Student:ChavisStackhouse,Governor’sSchoolforScience&Mathematics; Mentor:JamesA.Carson. 2006SouthCarolinaSummerProgramforResearchInterns.UniversityofSouthCarolinaHonorsCollege&SouthCarolina Governor’sSchoolforScienceandMath.Student:ShobhitVishnoi;Mentor:JamesA.Carson. 2005SouthCarolinaSummerProgramforResearchInterns.UniversityofSouthCarolinaHonorsCollege&SouthCarolina Governor’sSchoolforScienceandMath.Student:BridgetteMobley,SCGovernor’sSchoolforScience&Mathematics; Mentor:JamesA.Carson. 2005SouthCarolinaSummerProgramforResearchInterns.UniversityofSouthCarolinaHonorsCollege&SouthCarolina Governor’sSchoolforScienceandMath.Student:MaryBethSmith,SCGovernor’sSchoolforScience&Mathematics; Mentor:JamesA.Carson. 2003SouthCarolinaSummerProgramforResearchInterns.UniversityofSouthCarolinaHonorsCollege&SouthCarolina Governor’sSchoolforScienceandMath.Student:AlexisDemon,SCGovernor’sSchoolforScience&Mathematics; Mentor:JamesA.Carson. 2002SouthCarolinaSummerProgramforResearchInterns.UniversityofSouthCarolinaHonorsCollege&SouthCarolina Governor’sSchoolforScienceandMath.Student:SeanTran,SCGovernor’sSchoolforScience&Mathematics;Mentor: JamesA.Carson. 15 Scholarship:MentoredUndergraduateResearchFellows MagellonApprenticeCapstoneScholarFellowship.UniversityofSouthCarolina.Fall2015.$999stipend& Supplies.StudentSandraBlock,USCExerciseScienceUndergraduateStudent.Title:EffectofCancerCachexiaon AndrogenReceptorProteinExpressionDuringMuscleHypertrophy. MagellanScholarUndergraduateResearchFellowship.UniversityofSouthCarolina.Fall2015/Spring2016, $3,000stipend&supplies.Student:AlisonSaum,USCExerciseScienceUndergraduateMentor:JamesA.Carson Title:TheeffectsofOvarianFunctionandIL-6onMuscleMorphologyandInflammationinthecachecticmouse. MagellanScholarUndergraduateResearchFellowship.UniversityofSouthCarolina.Summer/Fall2013, $2,500stipend&supplies.Student:MatthewAugustine,USCExerciseScienceUndergraduateMentor:JamesA. CarsonTitle:TheeffectofAnabolicSteroidtreatmentonproteinturnoverwithcachexia MagellanScholarUndergraduateResearchFellowship.UniversityofSouthCarolina.Summer/Fall2013, $2,500stipend&supplies.Student:MakieraSimmons,USCBiologyUndergraduateMentor:JamesA.Carson Title:“Skeletalmusclewastinginlewislungcarcinomamodelofcachexia”. HonorsCollegeSURFResearchFellowship.UniversityofSouthCarolina.Fall/Spring2013, $2,500stipend&supplies.Student:MatthewAugustine,USCExerciseScienceUndergraduate Mentor:JamesA.CarsonTitle:TheeffectofAnabolicSteroidtreatmentonproteinturnoverwithcachexia HonorsCollegeSURFResearchFellowship.UniversityofSouthCarolina.Fall2012-2013, $3,000stipend&Supplies.Student:ElizabethDurante(USCBiology&DanceUndergraduate Mentor:JamesA.CarsonTitle:“LiverMetabolicFunctionwithCancerCachexia” HonorsCollegeSURFResearchFellowship.UniversityofSouthCarolina.Fall2012-2013, $3,000stipend&Supplies.Student:EmilyLerner(USCExerciseScienceUndergraduate) Mentor:JamesA.CarsonTitle:“MuscleoxidativemetabolismduringtheprogressionofCancer” HonorsCollegeSURFResearchFellowship.UniversityofSouthCarolina$3,000stipend&Supplies.$3,000stipend& Supplies.Student:AmberEngel(USCExerciseScienceUndergraduate)Mentor:JamesA.CarsonTitle:“MuscleContraction andProteinSynthesiswithCancerCachexia” HonorsCollegeSURFResearchFellowship.UniversityofSouthCarolina.Spring2011$3,000stipend&Supplies.Student: WesleyHardgrove(USCExerciseScienceUndergraduate)Mentor:JamesA.CarsonTitle:“Exercisepreventsmusclemass losswithcancercachexia” HonorsCollegeResearchFellowship.UniversityofSouthCarolina.2009-2010$3,000stipend&Supplies.Student:Aniruddh APatel(USCBiologyUndergraduate,currentlyinMedicalSchoolUofSouthCarolinaSchoolofMedicine)Mentor:JamesA. CarsonTitle:“Musclemasslosswithcachexia” HonorsCollegeResearchFellowship.UniversityofSouthCarolina),.2008–2009$3,000stipend&Supplies.Student:Jewel Sheehan(USCExerciseScienceUndergraduate,currentlyinMedicalSchoolUofNorthCarolina,ChapelHill)Mentor:James A.CarsonTitle:“Musclemasslosswithcachexia” HonorsCollegeResearchProject.UniversityofSouthCarolina2007.$1,000expenses Student:DaveManish(Senior,BiologyHonorsCollege.currentlyinMedicalSchoolWakeForestUniversity) Min/+ Mentor:JamesA.CarsonTitle:“EffectofexerciseanddietonApc miceintestinalapoptosisandCOX-2”. HonorsCollegeResearchProject.UniversityofSouthCarolina2007.$1,000researchexpenses Student:MattJepson(Senior,BiologyHonorsCollege,currentlyinMedicalSchoolUniversityofSouthCarolinaSchoolof Medicine)Mentor:JamesA.CarsonTitle:“Cachexia-inducedheartextra-cellarmatrixremodeling”. HonorsCollegeResearchProject.UniversityofSouthCarolina2007.$1,000researchexpenses Student:MikeKanwisher(Senior,BiologyHonorsCollege,currentlyinMedicalSchoolMedicalCollegeofGeorgia)Mentor: JamesA.CarsonTitle:“Fishoilsupplementationandcachecticmusclemass”. HonorsCollegeResearchFellowship.UniversityofSouthCarolina2006-2007.$3,000stipend&Supplies.Student: SamanthaIngram(USCBiologyUndergraduate)Mentor:JamesA.CarsonTitle:“Musclemasslosswithcachexia” HonorsCollegeResearchFellowship.UniversityofSouthCarolina2005-2006.$3,000stipend;10hrwk/researchfor academicyear.StudentManishJ.Dave(USCBiologyUndergraduate)Mentor:JamesA.CarsonTitle:“TheEffectofExercise andaHighFatDietontheIntestinalPolypIncidence 16 Scholarship:AWARDSMentoredResearchHighSchool&Undergraduates 2014DiscoveryDay,UniversityofSouthCarolina.April2014.2ndPlace,StudentUndergraduate ResearchAwardCompetition:ExerciseScience&PhysicalEducation. MathewAugustine,ExerciseScience,HonorsCollege,UniversityofSouthCarolina,Spring2014 “RadiationanddisusechangesinskeletalmusclemTORRegulation”(CarsonUndergraduateStudent). 2009DiscoveryDay,UniversityofSouthCarolina.April2009.1stPlace,StudentUndergraduate ResearchAwardCompetition:BiomedicalScienceCategory. Student:JewelSheehan,ExerciseScience,USCHonorsCollege(CarsonUndergraduateStudent). Submission:TheAssociationofGlucoseTolerancewithCachexiaintheAPCMin/+. 2009SouthCarolinaJuniorAcademyofScienceCompetition,April20091stPlace-HighSchoolWritten ScienceProjectPaper:BiomedicalScienceCategory. Student:SarahLancaster(GovernorsSchoolofScienceandMath,SummerResearchpositioninCarsonLab). Submissiontitled“TheEffectofTestosteroneonSkeletalMuscleMitochondrialBiogenesisandApoptosis. 2008SoutheasternChapterAmericanCollegeofSportsMedicine.BirminghamAL.2ndPlace-Student ResearchAwardCompetitionMasters/UndergraduateCategory. Student:MattJepson(CarsonUndergraduate&MastersStudent). Submission:TheEffectofCancerCachexiaontheExtracellularMatrixintheHypertrophyingAPCmin/+Mouse Heart 2004SouthCarolinaJuniorAcademyofScienceCompetition,April2004 2ndplacebothOralandWrittenHighSchoolScienceProjectCompetition:BiomedicalScienceCategory. Student:AlexisDeman(GovernorsSchoolofScienceandMath,SummerResearchpositioninCarsonLab). Submissiontitled“Skeletalmusclewastingandassociatedgeneexpressioninamousemodelofcoloncancer. 17 Scholarship:ChairofUndergraduateHonorsResearchThesis EmilyLearner,ExerciseScience,HonorsCollege,UniversityofSouthCarolina,Spring2014 “Musclegp130regulationofSkeletalMuscleMassandRegeneration” JamesA.Carsonchair MathewAugustine,ExerciseScience,HonorsCollege,UniversityofSouthCarolina,Spring2014 “RadiationanddisusechangesinskeletalmusclemTORRegulation” JamesA.Carsonchair ElizabethDurante,Biology&Dance,HonorsCollege,UniversityofSouthCarolina,Spring2014 “LiverFunctionwithcancerCachexia” JamesA.Carsonchair AndyPatel,ChemistryMajor,HonorsCollege,UniversityofSouthCarolina,Spring2010 “ChangesinOxidativeMetabolismwiththeprogressionofCachexiaintheApcMin/+Mouse” JamesA.Carsonchair CurrentlyinMedicalSchool,MedicalUniversityofSouthCarolina,2010 DaveManish,Biologymajor,HonorsCollege,UniversityofSouthCarolina,Spring2007, “EffectofexerciseanddietonApcMin/+miceintestinalapoptosisandCOX-2”. JamesA.Carsonchair CurrentlyinMedicalSchool,WakeForestUniversity,2007 MikeKanwisher,BiologyHonorsCollege,UniversityofSouthCarolina,Spring2007, “Fishoilsupplementationandcachecticmusclemass”. JamesA.Carsonchair CurrentlyinMedicalSchool,MedicalCollegeofGeorgia,2007 MarkWilson,ExerciseScienceHonorsCollege,UniversityofSouthCarolina,Spring2007,“Testosterone effectonmusclerecoveryfromdisuse”. JamesA.Carsonchair CurrentlyenrolledinMedicalSchool,UniversityofSouthCarolina,2008 MattJepson,BiologyHonorsCollege,UniversityofSouthCarolinaSpring2007, “Cachexia-inducedextra-cellarmatrixremodelingintheheart”. JamesA.Carsonchair CurrentlyinMedicalSchool,UniversityofSouthCarolina,Fall2009 18 Scholarship:MentoredUndergraduateResearchPrograms Summer2014NSFfundedSouthCarolinaAllianceforMinorityParticipationinResearch,Researchexperience forminorityundergraduatestudents.Student:XavierBell,MidlandsTechUndergraduate,Mentor:JamesA. CarsonProjecttitled:TBD. Spring2014,PresbyterianCollegeProgramforUndergraduateResearch,Students:StephanieDohmier.Devid Sellman,FloydNicholson.InconjunctionwithPresbyterianCollegefacultysuppliedbiologicalsamplesand laboratoryexpertisetoconduct3seniorcancerresearchprojects. Summer2009UniversityofSouthCarolinaEXPORTSummerResearchInternshipProgram,Research experienceforminorityundergraduatestudents.Student:SoniaThomas,UniversityofSouthCarolina, BiologyMajor,Mentor:JamesA.CarsonProjecttitled:“CachexiaintheApcMin/+mouse:TheroleofAkt signaling”. Summer2008USCSchoolofMedicineUndergraduateResearchInternshipProgram. ResearchexperienceforundergraduatesStudent:LovericaIrby,USCBiologicalSciencesMajor,Mentor: JamesA.CarsonProjecttitled:“Cancercachexiaandmitochondriallossinskeletalmuscle” Summer2008UniversityofSouthCarolinaEXPORTSummerResearchInternshipProgram,Research experienceforminorityundergraduatestudents.Student:JosephJohnson,ClaflinUniversityBiologyMajor, Mentor:JamesA.CarsonProjecttitled:“IntestinalGSK3-βphosphorylationintheApcMin/+mousemodelof colorectalcancer”. Summer2008UniversityofSouthCarolinaEXPORTSummerResearchInternshipProgram,Research experienceforminorityundergraduatestudents.Student:EricaLittles,ClaflinUniversityBiologyMajor; Mentor:JamesA.CarsonProjecttitled:“Theeffectoftestosteroneonskeletalmuscleoxidativecapacity”. Spring2008UniversityofSouthCarolinaDiscoveryDay,ResearchexperienceforUSCundergraduatestudents. Student:BethWolf,USCAthleticTrainingMajor;Mentor:JamesA.CarsonProject:“MRSAincidenceina collegevolleyballenvironment”. Summer2007UniversityofSouthCarolinaEXPORTSummerResearchInternshipProgram,Research experienceforminorityundergraduatestudents.Student:MykenziGibbs,USCExerciseScienceMajor; Mentor:JamesA.CarsonProjecttitled:“Aktactivationduringmuscleregeneration”. Summer2006PalmettoHealth–UniversityofSouthCarolinaCentersofResearchExcellenceSummerBiomedical ResearchInternshipProgram.Student:PujaDalal,USCExerciseScience,USCHonorsCollege.Mentor:JamesA. Carson.Projecttitled:“Androgenreceptorexpressionincachecticmousemuscle”. Summer2005PalmettoHealth–UniversityofSouthCarolinaCentersofResearchExcellenceSummerBiomedical ResearchInternshipProgram.Student:MattJepson,USCBiologyMajor,USCHonorsCollege.Mentor:JamesA. Carson.Projecttitled:“EffectofIL-6onmyosinexpressioninskeletalmuscleduringcachexia”. Summer2004PalmettoHealth–UniversityofSouthCarolinaCentersofResearchExcellenceSummerBiomedical ResearchInternshipProgram.Student:MeaganWaltmann,USCBiologyMajor.Mentor:JamesA.Carson. Projecttitled:“GeneexpressionassociatedwithintestinalpolypformationintheAPCminmouse”. Summer2003PalmettoHealth–UniversityofSouthCarolinaCentersofResearchExcellenceSummerBiomedical ResearchInternshipProgram.Student:EmersonGowerIII,USCBiologyMajor,USCHonorsCollege.Mentor:James A.Carson.Projecttitled:“Cardiachypertrophyandassociatedgeneexpressioninamousemodelforcoloncancer”. Summer2002PalmettoHealth–UniversityofSouthCarolinaCentersofResearchExcellenceSummerBiomedical ResearchInternshipProgram. Student:KristenCook,USCBiologyMajor.Mentor:JamesA.Carson. Projecttitled:“Theeffectofincreasedanddecreasedcontractileactivityonestrogenreceptorαexpressioninfemale ratsoleusmuscle”. 19 Scholarship:DoctoralStudentSupervision CompletedPhDsasChair(10) 10.KimbellHetzler,Fall2015,ExerciseScience,JamesCarsonChair Dissertationtitle:RoleofovarianfunctionincachexiaprogressionintheApcmin/+mouse Lefttopursue:Post-DoctoralResearchFellow,EmoryMedicalSchool 9.AditiiNarsale,Spring2014,ExerciseScienceDepartment,JamesCarsonChair Dissertationtitle:Roleofchronicinflammationonliverfunctionduringcachexiaprogressioninthe Apcmin/+mousemodel Lefttopursue:Post-DoctoralResearchFellow,Dept.Immunology,PennStateMedicalSchool 8.MelissaPupa,Fall2013,ExerciseScienceDepartment,JamesCarsonChair Dissertationtitle:TheRegulationofSkeletalMuscleMassandMitochondrialBiogenesisBygp130/STAT3 SignalingDuringCancerCachexia. Leftotpursue:PostDoctoralFellowSt.JudesChildrensResearchHospital,MemphisTN,Departmentof DevelopmentalandNeurobiology,PI:FabioDemontis 7.SuichiSato,Summer2012,ExerciseScienceDepartment,JamesCarsonChair Dissertationtitle:TheEffectofSEXandExerciseTrainingDuringTheProgressionofCancerCachexia. LefttoPursue:Post-doctoralResearchFellow,UniversityofLouisvilleMedicalSchool,Departmentof AnatomicalSciencesandNeurobiology;PI:Dr.AshokKumar, 6.KandyVelasquez,Summer2012,ExerciseScienceDepartment,JamesCarsonChair Dissertationtitle:TheEffectsofQuercetin,Curcumin,andExercise,ontheDevelopmentofCancer Cachexia. LefttoPursue:2013PostdoctoralfellowUSCSchoolofMedicine 5.JimWhite,Spring2011,ExerciseScienceDepartment,JamesCarsonChair Dissertationtitle:Regulationofmuscleproteinturnoverduringtheprogressionofcancercachexia. LefttoPursue:Post-doctoralResearchFellow,Dana-FarberCancerInstitute.DepartmentofCell Biology,HarvardMedicalSchool;PI:Dr.BruceSpiegelman 4.TyroneWashington,Spring2008,ExerciseScienceDepartment,JamesCarsonChair Dissertationtitle:Theroleofinterleukin-6duringskeletalmusclegrowthfollowingoverload-induced hypertrophyandrecoveryfromdisuse-inducedatrophy. LefttoPursue:TenuretrackfacultyUniversityofEvansville;2011-CurrentTenureTrackAssistant Professor,UniversityofArkansas 3.RayThompson,Summer2007,ExerciseScienceDepartment,JamesCarsonChair Dissertationtitle:Theroleofinterleukin-6oncardiacenlargementinamousemodelofcolorectalcancer LefttoPursue:ClinicalAssistantProfessorFaculty,UniversityofSouthCarolina 2.KristenMehl-Baltgalvis,Summer2007,ExerciseScienceDepartment,JamesCarsonChair Dissertationtitle:Theroleofinterleukin-6duringmusclewastinginamousemodelofcolorectalcancer LefttoPursue:PostdoctoralFellowatUniversityofMinnesota,Dr.DawnLowePI;2011-CurrentSenior Scientist,RigelPharmaceuticals 1.JosephMcClung,Summer2005,ExerciseScienceDepartment,JamesCarsonchair Dissertationtitle:Theroleofestrogensignalingregulationinskeletalmusclerecoveryfromdisuseatrophy LefttoPursue:PostdoctoralresearchFellowatUniversityofFlorida,ScottPowersPI;2011Research AssociateDukeUniversityMedicalSchool;Current:2013facultyEastCarolinaSchoolofMedicine, PhysiologyDept. 20 ExternalDissertationreviewer:AyieshaSaleem,YorkUniversity,TorontoCanadaAugust2013 CompletedPhDsasmemberofdissertationcommittee(9) JennyStiener,Fall2012,ExerciseScienceDepartment,MarkDavis,JCarsoncommitteemember. BradGordon,Spring2012,ExerciseScienceDepartment,MattKostek,JCarsoncommitteemember. DianaDelgado,Summer2012,ExerciseScienceDepartment,MattKostek,JCarsoncommitteemember. YinXiong,Fall2006,BiomedicalSciencesResearchProgram,UniversityofSouthCarolinaSchoolof Medicine.BillHrusheskychair.JCarsoncommitteemember. MartinCarmichael,Fall2005.ExerciseScienceDepartment,MarkDavis,JCarsoncommitteemember. AdrianBrown,Spring2004,,ExerciseScienceDepartment,MarkDavis,JamesCarsonCommitteemember. JoelAtance,Spring2004,DevelopmentalBiology&AnatomyDepartment,UniversityofSouthCarolina SchoolofMedicine.WayneCarverChair,JamesCarsoncommitteemember. AngelaMurphy,Summer2004,ExerciseScienceDepartment,MarkDavis,JCarsoncommitteemember. LauraFulk,Fall2004,ExerciseScienceDepartment,GregHand,JCarsonCommitteemember. InProgressDoctoralCandidatesasCommitteeChairandAdvisor SongGao,AppliedPhysiology,ExerciseScience,fromIntegratedBiomedicalSciencesProgramprojected 2016,JamesCarsonChair JustinHardee,AppliedPhysiology,ExerciseScience,Projected2016,JamesCarsonChair DennisFix,AppliedPhysiology,ExerciseScience,Projected2017,JamesCarsonChair BrandonVanderveen,AppliedPhysiology,ExerciseScience,Projected2019,JamesCarsonChair OtherMentoredResearch 2004AmericanPhysiologicalSocietyFrontiersinPhysiologyProfessionalDevelopmentFellowship. Acompetitivesummerfellowshipprogramtoprovidealearning/researchopportunityforpublicschool scienceteachersofferedbytheAmericanPhysiologicalSociety. Participant:BetsyScarborough.RichlandCountySchoolDistrict1MiddleSchoolScienceteacher. Mentor:JamesA.Carson.,Project:“LiverCatalaseactivityduringCancerCachexia”. Scholarship:Post-DoctoralFellowSupervision MariaLima,PhD; JonathonBrock,PhD; 2009–2011(co-supervisedwithDr.JohnBaynes) 2007-2008(co-supervisedwithDr,JohnBaynes) 21 Scholarship:MastersStudentSupervision ChairMaster’sThesisCommittee(5) DennisFix,Fall2013,Thesistitle:Theeffectofradiationdoseonskeletalmusclemorphology. JoshuaMangum,Fall2013,Thesistitle.MetabolicplasticityofcachecticSkeletalMuscle SoniaThomas,Spring2011Thesistitle“SuccinationinDiabetes” MarkCairns,Summer2008(currentlyinMedicalSchool,U.SouthCarolina)Thesistitle“Endotoxinandcachexia” JamieMcClellan,Spring2008(graduatePhDUSCMedical)Thesistitle“pyridoxamineandcachexia” Master’sThesisCommitteeMember RyanFalick,Spring2014 LaurenVerviake,Spring2013 ClaireGroschwitz,Spring2005, SupervisedExerciseScienceMastersStudentProjects(8) JoshuaJefferies,2015,“StrengthNormsforSouthCarolinaHighSchoolAthletes” NathanRice,Spring2014,“StrengthChangesinHighSchoolAthletes” JohannesAartun,Spring2012,“ExerciseandCancerSurvival” KarinaHowell,Summer2010“Trainingforlandingandcuttingstabilityinthefemaleathlete” BrandonCain,Spring2010“IL-6andColorectalCancer” NicoleReese,Fall2009,title“COPDandExercise” MattJepson,Spring2009,title“AdiposeTissueHypoxia:LinkingObesitytoInsulinResistance AprilWilson,Spring2005,title“NSAIDSandrecoveryfrommuscledamage” JeremiahBlankenship,Spring2005,title“MixedMethodsofMaximalForcetraining” AdrianPinasco,Spring2002,title“ThePhysiologicbasisforSoccertraining” Othergraduatestudentsfunded/supervisedasresearchGA’sandunderJamesCarson’s supervisionforatleast1semester JohannesAartun,fall2010–present,AppliedPhysiologyMSStudent SoniaThomas,Fall2009–2011,AppliedPhysiologyMSstudent AmandaClifford,Fall2009,AppliedPhysiologyMSstudent AshlyArtese,Spring–summer2009–Summer2009,AppliedPhysiologyMSstudent NicoleReese,Fall2008–Fall2009present,AppliedPhysiologyMSstudent MattJepson,Fall2007–Spring2009,AppliedPhysiologyMSstudent AprilWilson,Fall2004-Spring2005,ExerciseScienceGraduateStudentgraduatedSpring2005. ClaireGroschwitz,spring2002–spring2003,ExerciseScienceundergraduateandMaster’sstudent,acceptedinto VeterinarySchoolfall2004. StevenChen,2002spring–2002summer,ExerciseScienceMastersprogram, RobinBrewer,2001fall–2002spring,ExerciseScienceMastersstudent, JillMaxwell,fall2001,ExerciseScienceMastersprogram,graduatedin2003. WonJunLee,fall2000–spring2003,ExerciseScienceDoctoralstudent,transferredtoPharmacy. TonyaZier,fall2000–spring2001,ExerciseScienceMaster’sStudent,graduatedin2001. PaulBurkhart,summer2000,ExerciseScienceGraduateStudent,graduatedsummer2000. 22 Scholarship:MentoredGraduateStudentFellowships&Grants SPARCGraduateResearchGrant,UniversityofSouthCarolina.2015-16 Student:JustinHardee(EXSCGraduateStudent);PrincipalInvestigator:JamesA.Carson.. Title:mTORC1RegulationofMuscleProteinSynthesisinaMouseModelofCancerCachexia$5,000 AmericanCollegeofSportsMedicineGraduateStudentResearchAward.2015-2016 Student:JustinHardee(EXSCGraduateStudent);PrincipalInvestigator:JamesA.Carson.. Title:SkeletalMuscleResponsetoLow-andHigh-FrequencyElectricalStimulation.$4,842Expenses AmericanCollegeofSportsMedicineGraduateStudentResearchAward.2013-2014 Student:MelissaPuppa(EXSCGraduateStudent);PrincipalInvestigator:JamesA.Carson.. Title:Theregulationofmitochondrialplasticitybygp130rinskeletalmuscleaftercontraction.$4,700Expenses SouthEastAllianceforGraduateEducationandtheProfessoriate(SEAGEP),2010-2011AcademicYear Student:KandyVelazquez(EXSCDoctoralCandidate,Mentor:JamesCarson$4,000Stipend SouthCarolinaSpaceGrantFellowship.SouthCarolinaSpaceGrantConsortium2005–2006 Student:TyroneWashington(EXSCGraduateStudent);PrincipalInvestigator:JamesA.Carson. Title:“Estrogen’sroleinmuscleregrowthfromatrophy”.$7,500Stipend AmericanCollegeofSportsMedicineGraduateStudentResearchAward.2004-2005 Student:KristenMehl(EXSCGraduateStudent);PrincipalInvestigator:JamesA.Carson.. Title:“EicosapentaenoicAcidandExerciseasaCachexiaCountermeasure”.$5,000ResearchExpenses GatoradeSportsScienceInstituteGraduateStudentResearchProgram.,2004–2005 Student:KristenMehl(EXSCGraduateStudent);PrincipalInvestigator:JamesA.Carson. Title:“ConjugatedLinoleicAcidandExerciseasaCachexiaCountermeasure$1500researchExpenses AmericanCollegeofSportsMedicineNASAGraduateResearchGrant.($5,000),2003-2004 Student:JosephM.McClung(EXSCGraduateStudent);PrincipalInvestigator:JamesA.Carson. Title:“EffectofanabolicsteroidsonRhoAlocalizationduringrecoveryfromdisuseskeletalmuscleatrophy”. AmericanFederationForAgingGlennStudentAwardForResearchInTheAreaOfTheBiologyOfAging. Research($5,000),2002-2003.Student:RaymondThompson(EXSCGraduateStudent);PrincipalInvestigator: JamesA.Carson.Title:“EffectofInflammationonAgedSkeletalMuscleRegeneration”. AmericanCollegeofSportsMedicineNASASpacePhysiologyResearchGrant.($2,500),2002-2003. Student:JosephMcClung(EXSCGraduateStudent);PrincipalInvestigator:JamesA.Carson. Title:“β1IntegrinSignalingduringdisuseskeletalmuscleatrophy”. GatoradeSportsScienceInstituteGraduateStudentResearchProgram.($500),2002-2003. Student:JosephMcClung(EXSCGraduateStudent);PrincipalInvestigator:JamesA.Carson Title:“Leucineadministrationasacountermeasureforunloadinginducedatrophyinratskeletalmuscle. GatoradeSportsScienceInstituteStudentGrantProgram.($500),2002-2003. Student:ChristopherBopp(EXSCGraduateStudent);PrincipalInvestigator:JamesA.Carson. Title:“CreatineSupplementationEffectsonCardiacGeneExpression. SouthCarolinaSpaceGrantConsortiumSouthCarolinaSpaceGrantFellowship,($5,100),2001-2002 Student:TyroneWashington(EXSCGraduateStudent);PrincipalInvestigator:JamesA.Carson. Title:“LactateDehydrogenaseActivity,andmRNAabundanceinatrophyingandhypertrophyingmuscle. SouthCarolinaSpaceGrantConsortiumSouthCarolinaSpaceGrantFellowship,($7,175),2001-2002. Student:JosephMcClung(EXSCGraduateStudent);PrincipalInvestigator:JamesA.Carson. Title:“MechanicalSignalingDuringCountermeasurestoreducedisuseatrophy”. 23 Scholarship:AWARDS:MentoredGraduateStudentResearch 2015SoutheasternChapterAmericanCollegeofSportsMedicine.JacksonvilleFL,Feb.2015. 1stPlace–DoctoralStudentResearchAward.Student:JustinHardee(Carsondoctoralstudent). Submissiontitled“Cachecticskeletalmuscleresponsetocontractions:aroleforStat3signaling”. 2013SoutheasternChapterAmericanCollegeofSportsMedicine.GreenvilleSC,Feb.2013. 1stPlace–DoctoralStudentResearchAward.Student:MelissaPuppa(Carsondoctoralstudent). Submissiontitled“Cachecticskeletalmuscleresponsetoanovelboutoflowfrequencystimulation”. 2010GraduateStudentDay,UniversityofSouthCarolina,April2010. 1stPlace,GraduateStudentResearchAward,Health&LifeSciencesCategory(Poster). Student:JamesWhite(Carsondoctoralstudent).Submissiontitled“Skeletalmuscleproteinsynthesisand cancercachexiaintheApcMin/+mouse 2007MidwesternChapterAmericanCollegeofSportsMedicine.October2007 OutstandingDoctoralStudentOralCommunicationsPresentation.Student:TyroneWashington(Carson DoctoralStudent)Submission:Interleukin-6deficiencyattenuatestherecoveryofgastrocnemiusmusclemass fromdisuse-inducedatrophy. 2006Southe3asternChapterAmericanCollegeofSportsMedicine.Charlotte,NorthCarolina,Feb.2006. 2ndPlace-GraduateStudentResearchAward.Student:KristenMehl(Carsondoctoralstudent). Submissiontitled“TheRoleofIL-6inCancerCachexiaInducedMuscleWastingintheApcMin/+mouse”. 2005SouthCarolinaNutritionResearchConsortiumResearchSummit––.Columbia,SCNovember2005. FirstPlace-GraduateStudentPosterAward;Student:KristenMehl(Carsondoctoralstudent). Submission“Theinteractionofahigh-fatdietandexerciseonintestinalpolypdevelopmentinApcMin/+mice”. 2004SoutheasternChapterAmericanCollegeofSportsMedicine.–.Atlanta,Georgia,Jan.2004. 3rdplaceGraduateStudentResearchAward.Student:KristenMehl(Carsondoctoralstudent) Submissiontitled“PhysicalactivitydecreasesintestinalpolypdevelopmentintheAPCmin+/-mouse”. 2003UniversityofSouthCarolina–GraduateStudentDayOralPresentation. ResearchAward;Health($400).PrincipalStudentInvestigator:JosephM.McClung(CarsonDoctoral Student).Submission:“Pro-inflammatorycytokineexpressioninagedregeneratingskeletalmuscle.” 2002UniversityofSouthCarolinaGraduateStudentDayColumbia,SC,March2002. OralpresentationResearchAward($400).Student:JosephMcClung(CarsonDoctoralStudent) Submission:“RhoAinductionbyfunctionaloverloadandnandrolonedecanoateinratskeletalmuscle”. 2002SoutheasternChapterAmericanCollegeofSportsMedicine.Atlanta,Georgia. 1stPlace-OutstandingDoctoralStudentResearchAward($500).Student:JosephMcClung(CarsonDoctoral Student)Submissiontitled“RhoAinductionbyfunctionaloverloadinratskeletalmuscle”. 2002BetaKappaChiScientificHonorSociety/NationalInstituteofScienceBrookhaven GraduateStudentOralPresentationResearchAward($500).Student:TyroneWashington.Submission: “Decreasedlactatedehydogenaseactivityattheonsetoffunctionaloverloadinratplantarismuscle”. 2002BetaKappaChiScientificHonorSociety/NationalInstituteofScienceBrookhaven. GraduateStudentOralPresentationResearchAward($300).Student:JosephMcClung.Submissiontitled “RhoAexpressionandskeletalmusclehypertrophy” 2002NationalInstituteofScience,Columbia,SC,2002. GraduateStudentOralPresentationResearchAward($300).Student:JosephMcClung Submissiontitled“RhoAinductionbyfunctionaloverloadandnandrolonedecanoateinratskeletalmuscle”. 24 Scholarship:ResearchGrants PENDING R21(AChandaPI) 1/1/2017–12/30/2018 0.6calendar NationalInstitutesofHealth/NCI $390,875(2yr) Status:Pending CarsonJACo-I ImpactofDietarySeleniumSupplementationonMicrobiomeandMetaboliteProfilesinApcMINMice. R21(CarsonPI) 07/1/2016–6/30/2018 1.2calendar NationalInstitutesofHealth/NCI $402,875(2yr) Status:Pending LinkingCancerCachexiatoGutDysbiosis VAMerit(GinsbergJ,DornVA) 7/1/2016–6/302019 0.6calendar VeteransAffairs–DornResearchInstitute $567,454(3yr–subcontract) CarsonJACo-I(subcontract) AutonomicBluntingandRestorationinVeteranswithGulfWarSyndrome:TheHeartRate VariabilityIndexofCognitivePerformance,Fatigue,andRest/Activity R21(KohHPI,USCExerciseScience) 07/1/2016–6/30/2018 1.2calendar NationalInstitutesofHealth/NIAMS $391,715(2yr) Status:Pending CarsonJACo-I TheRoleofTRB3inDenervation-andCancerCachexia-inducedInsulinResistance RO1(TothMPI,VermontCollegeofMedicine) 06/1/2016–5/30/2021 0.6calendar NationalInstitutesofHealth/NIAMS $170,197(subcontract) Status:Pending CarsonJACo-I(subcontract) SkeletalMuscleAtrophyandDysfunctioninHumanCancer ACTIVE RO1(CarsonPI) 04/15/2014–2/28/2019 2.0calendar NationalInstitutesofHealth/NCI $1,483,315(5yr);$296,6631yr Status:Funded Otherinvestigators:AngelaMurphy,MarkPena CachexiainApcMIN/+mice:TheroleofIL-6 5P30GM103336-02 SeedGrant(ChatterjeeS.PI) 09/1/2015–8/30/2016 Center ForColonCancerResearchatUSC $50,000(1yr) Status:Funded CarsonJACo-I TLR4-inducedmiRsasmolecularsignatureinNALFDpotentiationofcolonneoplasia 5P30GM103336-02(BergerPI) 7/1/2013–6/30/2018 1.0calendar NIH/NIGMS CenterForColonCancerResearch. 25 AssociateDirector(Carson) PhaseIIICenterGrant 26 SelectedGrantFundingCompleted NationalInstitutesofHealthRelatedFunding(over3.4milliondollars) RO1CA121249-01A2(CarsonPI) April2008–March2013 2.4calendar NationalInstitutesofHealth/NationalCancerInstitute: $1,118,000(Total costs) Title:CachexiainApcMIN/+mice:TheroleofIL-6 R37DK019971-31(PIBaynes;Carsonco-PI)Sept2007–July2011 1.5calendar SNationalInstitutesofHealth/NationalInstituteofDiabetes&DigestiveDiseases(NIDDK/NIH) Title:GlycationofProteininDiabetes $1,492,100(Total Costs) R21CA135377-01A1(PIMurphy;CarsonCo-I) Sept2009–August2011 0.36calendar NationalInstitutesofHealth/NationalCancerInstitute $540,000totalcost Title:CurcuminandQuercetininColonCancer:RoleofMacrophage-InducedInflammation RO3AR051434-01A1(CarsonPI) July2005–June2007 2.4calendar NationalInstitutesofHealth/NIAMS $139,130totalcost Title:Androgen’sroleinskeletalmuscleregeneration F32AR008328-01(CarsonPI,BoothMentor) June1994–May1997 12.0calendar NationalResearchServiceAward,Post-DoctoralTrainingFellowship, $75,000 NationalInstituteofArthritisandMusculoskeletalandskindiseases,TheNationalInstitutesofHealth,. Title:Chickenα-actinpromoterfunctionduringhypertrophy NationalInstitutesofHealthNationalCenterRelatedFunding Source:NationalInstitutesofHealthGrantP20fromtheNationalCenterforResearchResources,U SouthCarolinaCOBRECenterforDietarySupplements&Inflammation/PilotProjectGrant Dates:March2013–February2014 Funds:$10,000 Principalinvestigator:JamesA.Carson Title:Quercetinsupplementationandthepreventionofgutbarrierdysfunctionduringcancercachexia Source:NationalInstitutesofHealthGrantP20RR-017698fromtheNationalCenterforResearch Resources,UniversityofSouthCarolinaColorectalCancerCOBREProgram CompletedDates:July2010–June2012 Funds:$279,00(total) PrincipalInvestigator:RajaFayd,AssistantProfessorExerciseScienceMentor:JamesA.Carson(1 monthsalary) Title:TheroleofSeleniumandadiponectininchronicinflammation-inducedcoloncancer Source:NationalInstitutesofHealthGrantP20RR-017698fromtheNationalCenterforResearch Resources,UniversityofSouthCarolinaColorectalCancerCOBREProgramStatus:Funded,SeedGrant ProgramDates:11/1/10–6/31/11Funds:$50,000(Direct)PrincipalInvestigator:JamesA.Carson Title:Gutbarrierdysfunctionin2distinctmodelsofcancercachexiainmice 27 Source:NationalInstitutesofHealthGrantfromtheNationalCenterforResearchResources SharedInstrumentationGrant Dates:February2010PrincipalInvestigator:RobertPriceFunds:$381,491(Direct)Investigator:James Carson(instrumentationgrant);contributedtograntproposal Title:IVISSpectrumImagingSystemfortheUniversityofSouthCarolina Source:NationalInstitutesofHealthGrantP20RR-017698fromtheNationalCenterforResearch Resources,UniversityofSouthCarolinaColorectalCancerCOBREProgramSeedGrantProgramDates: 7/1/08–6/31/09Funds:$50,000(Direct)PrincipalInvestigator:JamesA.Carson Title:GutbarrierDysfunction:ThetriggerforcachexiainApcMin/+mice Source:NationalInstitutesofHealthGrantP20RR-017698fromtheNationalCenterforResearch Resources,UniversityofSouthCarolinaColorectalCancerCOBREProgramSubmission:June2004, ProjecttargetinvestigatorDates:9/1/05–6/31/07Funds:$140,000 PrincipalInvestigator:JamesA.Carson(COBRETargetPI) Title:TheeffectofphysicalactivityonintestinalpolypformationintheAPCminmouse Source:NationalInstitutesofHealthGrantP20RR-017698fromtheNationalCenterforResearch Resources,UniversityofSouthCarolinaColorectalCancerCOBREProgram Submission:October2003,seedgrantawardStatus:Funded,SeedGrantDates:1/03–7/04Funds: $80,000 PrincipalInvestigator:JamesA.CarsonTitle:Theeffectofphysicalactivityonintestinalpolyp formationintheAPCminmouse OtherCompletedFunding Source:AmericanHeartAssociationMid-AtlanticRegion,BeginningGrantinAid Submission:November1999Status:FundedGrant#:0060173UDates:7/2000–6/2002P rincipalInvestigator:JamesA.Carson Title:SmoothmusclegammaactingeneactivationbyRhoA:Apotentialroleinsmoothmusclemechanicalsignaling Source:AmericanFederationForAgingResearch(AFAR),AFARResearchGrantProgram Submission:December1999Status:FundedDates8/1/2000–6/31/2002Funds:$50,000PrincipalInvestigator:JamesA. CarsonTitle:SerumResponseFactor’sroleinagedskeletalmuscle’sbluntedremodelingresponsetochronicstretch Source:TheOhioStateUniversityGraduateSchool. Submission:1992Status:FundedDates1992-1993Funds:$900 PrincipalInvestigator:JamesA.Carson;Mentor:StephenAlway Title:TheeffectofagingonfibernumberandsatellitecellactivationintheanteriorlatissimusdorsimuscleoftheJapanese Quailafterstretch-overload Source:NationalScienceFoundation/EPSCoRgrant#EPS-0132573andNIH/BRINgrant#8-PORR13461.Collaborative ResearchProgram. Submission:February2002Status:Funded,expiredDates:5/02–12/03Funds:$75,000($45KtoDr.Carson) PrincipalInvestigator:JamesA.Carson&LarryLowe(BenedictCollege) Title:AgedMuscle’sDecreasedRegenerativeCapacity:Inflammation’sCriticalRole. AspireIProgram(Carson), 05/091/2013–9/31/2014 0.0calendar UniversityofSouthCarolinaVPResearchOffice $15,000(1year) ROLEOFIL-6SIGNALINGONSKELETALMUSCLEWASTINGINLEWISLUNGCARCINOMAMODELOFCACHEXIA FundstogeneratepreliminarydataforgrantsubmissionrelatedtoIL-6inducedcachexia. 28 SeedGrant(Carson) 03/01/214–02/28/215 0.0calendar NationalInstitutesofHealthGrantP20RR-017698fromtheNationalCenterforResearchResources,UniversityofSouth CarolinaColorectalCancerCOBREProgram $5,000(1yr) Title:Measurementofmusclefibertypespecificproteinsynthesisrates Source:ArnoldSchoolofPublicHealthSeedGrant (USCCompetitiveinternal) Status:Funded-USCinternalDates:June2007–May2008Funds:$5,000(DirectCosts) Principalinvestigator:JamesA.Carson) Title:InflammationandCachexiainApcMIN/+mice Source:ResearchConsortiumonChildrenandFamilies/USC Status:Funded–USCinternalDates:May2006–April2007Funds:$19,998 PrincipalInvestigator:MeganC.Kurlychek,AsstProf.USCCriminology&CriminalJustice Investigator:JamesA.Carson Title:Performanceenhancingdrugs:Afeasibilitystudyinassessingmotives,correlates,andoutcomesamonga generalpopulationofyoungadults. Source:PalmettoHealth/SouthCarolinaCancerCenter Status:Funded(#SCCCRO6-04);StateinitiativeDates:May2006–April2007Funds:$24,500 PrincipalInvestigator:GregHand,Assoc.Prof.EXSC;Investigator:JamesA.Carson Title:Theeffectoflong-termphysicalactivityonmarkersofmetabolicdysfunctionandinflammationinelderly prostatecancersurvivors. Source:SouthCarolinaNutritionResearchConsortium Submission:April2004Status:FundedDates 8/1/04–7/31/05 Funds:$20,000 Principalinvestigator:JamesA.Carson,co-investigatorDr.StephanieMuga Title:Nutrition&Exerciseinterventiononintestinalpolypformation. Source:NationalScienceFoundation/EPSCoRgrant#EPS-0132573andNIH/BRINgrant#8-PORR13461. CollaborativeResearchProgram. Submission:October2003,Competitive6monthRenewalofCollaborativeproject Status:Funded,expiredDates:12/1/03–6/30/04Funds:$35,000($30,000toDr.CarsonatUSC) PrincipalInvestigator:JamesA.Carson&LarryLowe(BenedictCollege) Title:AgedMuscle’sDecreasedRegenerativeCapacity:Inflammation’sCriticalRole. Source:UniversityofSouthCarolinaResearchSupportProgram,DevelopmentalGrant Submission:January2002Status:FundedDates9/1/2002–6/30/2003Funds:$15,000 PrincipalInvestigator:JamesA.Carson Title:AgedMuscle’sDecreasedCapacityForRegeneration:TheAndrogenReceptor’sRole Source:UniversityofSouthCarolinaSchoolofMedicine–SchoolofPublicHealthCollaborativeresearch IncentiveProgram Submission:2002Status:FundedDates9/1/2002–8/31/2003Funds:$20,000 PrincipalInvestigators:MarleneWilson&GregoryHandCollaborativeteamMember:JamesCarson Title:Anxiety,PhysicalActivity,andOpioidPeptides Source:.UniversityofSouthCarolinaCollegeofNursingCenterForHealthPromotionandRiskReductionin SpecialPopulations. Submission:2002Status:FundedDates9/1/2002–8/31/2003Funds:$10,000 PrincipalInvestigators:GregoryHand&KennethPhillips,Investigativeteam:JamesA.Carson Title:DevelopmentalGrant.“EffectsofAcupunctureandNursingBackRubonStress-inducedoraldiseasein HIV+Individuals. Source:SouthCarolinaSpaceGrantConsortium,TravelGrant/SouthCarolinaSpaceGrantConsortium Submission:February2000Status:FundedDates7/1/2000–2/28/2001Funds:$8,000/6months PrincipalInvestigator:JamesA.Carson Title:AndrogenTherapyAsACounterMeasureAgainstUnweighting-InducedSkeletalMuscleAtrophy 29 GrantSubmissionsNotFunded Submitted2015,notfunded RO1(MurphyAPI;CarsonCo-I) 04/1/2016–3/30/2021 0.6calendar NationalInstitutesofHealth/NCI $1,688,750(5yr) Title:TargetingMCP-1inObesity-EnhancedBreastCancer Submitted2014,notfunded NASASpaceBiology(Carson,subCo-I) 12/01/14-12/31/17 $250,000year1 1.0calendar MechanismsforWhole-LimbAtrophyDuringLongDurationSpaceflight.Thisresearchproposaladdressthe degradationofskeletal,joint,andmuscletissueinthehindlimbfromlongtermspaceflightandrecoveryupon reloading NIH/NCIR21(Fayad;Carsonco-I)$393,710(Totalcosts2yr);09/01/2014–08/30/2016 3.0calendar Co-investigator:JamesA.CarsonExerciseandAdiponectin:Roleinchronicinflammation-inducedcoloncancer Submitted2013,notfunded NIH/NIAMS1R21AR065015-01R21(Carson) June2014–May2016 $342,250year12.0calenda Title:Theroleofgp130receptorsignalinginload-inducedgrowth Intheproposedstudywewillevaluatetheroleofmusclegp130receptorandSTAT3signalingduringoverload inducedhypertrophyanddisuseatrophyinotherwisehealthymice.. Scored 33 percentile, reformatting for submission R21NationalInstitutesofHealth/NCIStatus:SubmittedJune2013,Scoredresubmitting, Dates:April2014–March2016Funds:$393,710(Totalcosts2yr); Principalinvestigator:RajaFayad,AsstProfessorUSCEXSCCo-investigator:JamesA.Carson(3calendar months)Title:ExerciseandAdiponectin:Roleinchronicinflammation-inducedcoloncancer AmericanDiabetesAssociation.Status:resubmissionNotfundedDates:January2014–December2017 Funds:$345,000(Totalcosts)Principalinvestigator:JamesA.Carson(1calendarmonth) Otherinvestigators:RajaFayad,AngelaMurphyTitle:TheMusclegp130Receptor’sRoleinMuscleProteinand MetabolicRegulationDuringHighFatDiet-inducedObesity. Submitted2012,notfunded R21NationalInstitutesofHealth/NIAMS.Status:Scored42,notfunded,willresubmit Dates:June2013–May2015.Funds:$685,000(Totalcosts2yr);$342,250firstyear.Principalinvestigator:James A.Carson(2calendarmonths).Title:Theroleofgp130receptorsignalinginload-inducedgrowth Source:R01NationalInstitutesofHealth/NationalCancerInstitute.Status:Scored30,inrevisionandwill resubmit2013.Dates:April2013–March2018.Funds:$1,756,250(Totalcosts5yr);$342,250firstyear. Principalinvestigator:JamesA.Carson(2calendarmonths).Otherinvestigators:AngelaMurphy,J.MarkDavis Title:CachexiainApcMIN/+mice:TheroleofIL-6 Source:AmericanDiabetesAssociation Status:NotFundedg,BasicScienceGrantDates:January2013– December2016Funds:$345,000(Totalcosts)Principalinvestigator:JamesA.Carson(1calendarmonth) Otherinvestigators:RajaFayadTitle:TheMusclegp130Receptor’sRoleinMuscleProteinandMetabolic RegulationDuringHighFatDiet-inducedObesity. Submitted2011,notfunded NationalSpaceBiomedicalResearchInstitute,Status:Notfunded,submittedDecember2011;Funds:$544,000 (totalcost)subcontracttoUSCJCarson;PrincipalInvestigator:TedBateman,AssociateProfessor,UNC-Chapel Hill,Co-investigator:JamesA.Carson(1monthsalary);Title:IntegratedWholeJointHealth:TimeCourseof MusculoskeletalandCartilageDegradation/RecoveryforMicrogravityandSpaceRadiation NationalInstitutesofHealth/NationalCancerInstitute,Status:Scored,notfunded,resubmit,Dates:4/1/12– 3/31/14;PrincipalInvestigator:ElizabethMurphy,AssistantProfessor,USCSchoolofMedicine,Co-investigator: 30 JamesA.Carson(0.27months);Funds:$376,760(Total)Title:MacrophagesinHighFatDietEnhanced ColorectalCancer:RegulationbymiRNA-155 NationalInstitutesofHealth/NIAMS,4/1/12–3/31/14,PrincipalInvestigator:MatthewKostek,Assistant ProfessorEXSC,USC,Co-investigator:JamesA.Carson(0.9months),Funds:$379,850(Total)Title:PGC1-alpha, Utrophin,andMuscleFunctionResponsetoResveratrolinmdxMice NationalInstitutesofHealth/NationalCenterforResearchResources,Dates:4/1/12–3/31/13,Principal Investigator:RobertPrice,USCSchoolofMedicine,Co-investigator:JamesA.Carson Funds:$702,999(Total)Coreinstrumentationinstrument,Title:GATAN3ViewSerialBlockFaceScanning ElectronMicroscopeonaZeissSigmaSEM Submitted2010,notfunded NationalInstitutesofHealth/NationalCancerInstitute,Status:R01notfundedresubmit,Submitted:June 2010,Funds:$1,500,000totalcost;PrincipalInvestigator:AngelaMurphy(AssistantProfessor,USCSchoolof Medicine),Co-PrincipalInvestigator:JamesCarson(5%effort) Title:Multi-targetedpreventionofobesityenhancedcancerbyquercetin:RoleofSIRT1 NationalInstitutesofHealth,Status:R21notfundedsubmissionTBD,Submitted:June2010,Funds:$404,250 totalcost;PrincipalInvestigator:JeffPatton(AssociateProfessor,USCSchoolofMedicine),Co-Investigator: JamesCarson(subcontract) Title:PathogenesisofMitochondrialMyopathyandSideroblasticAnemia (MLASA) CancerPrevention&ResearchInstituteofTexas,Status:Submitted:June2010;PrincipalInvestigator:Yi-PingLi (AssociateProfessor,UniversityofTexasMedicalSchoolHouston),Co-investigator:JamesCarson(subcontract) Title:TheRoleofAutophagyinCancerCachexia NationalInstitutesofHealth/NationalInstituteofDiabetes&DigestiveDiseases(NIDDK/NIH) ,Submission: RO1submittedFebruary2010,Status:Notfunded,plantoreviseandresubmit,Funds:$1,138,400(Totalcosts), Principalinvestigator:NormaFrizzell,Co-PI:JamesA.Carson(0.9calendarmonths) Title:TheRoleofSuccinationinEndoplasmicReticulumStressintheDiabeticAdipocyte Submitted2009,&earlier,over45grantsubmissionsnotfunded 31 Scholarship:SpeakingPresentations ScheduledInvitedPresentations 3rdCancerCachexiaConference,September2016,WashingtonDC,invitedsymposiumspeaker. 2016 UniversityofIndianaUniversitySchoolofMedicine,February25,2016,IndianapolisIN,Invitedlecture, canceledduetoflightissueswithweather. 2016AdvancesinSkeletalMuscleBiologyinHealthandDisease,January2016,GainesvilleFL,Invited symposiumspeaker. 2015 InternationalCachexiaConference,ParisFrance,December2015,Invitedspeakersymposiummuscle mitochondriaandcachexia. AmericanCollegeofSportsMedicineNationalMeeting.SanDiego.InvitedSpeakerinasymposium “FatiguewithdiseaseandInflammation”andtalktitle“Combattingcancerfatigue:Theinteractionof inflammationandexercise.”May2015. ExperimentalBiologyMeeting,AmericanPhysiologicalSociety,SessionChair,BostonMA.EEP Symposiumtitle“MolecularMechanismsofMuscleAtrophy,HypertrophyandMicroRNA”.April2015. WoffordCollege,SpartanburgSC,InvitedSpeaker.“PhysicalActivityandHealth:ExerciseScienceat USC.”January2015 2014 UniversityOfArkansasMedicalSchoolGrandRoundsEndocinology,InvitedLittleRockAR,December 2014.Title“RegulationofCancerCachexia-inducedMuscleWastingbythegp130receptor:Arolefor exercise”. UniversityOfNebraskaMedicalSchoolCancerBiologySeminarSeries,InvitedOmahaNE,November 2014.Title“Theroleofthegp130receptorincancercachexiaprogression”. InternationalCachexiaConference,MontrealCanada,InvitedSymposiaParticipant,September20 2014.“MitochondriaDysfunctionandCancerCachexia. UniversityofKentuckyMedicalSchool,MuscleBiologySeminarSeries,LexingtonKentucky.Invited speaker.“Musclewastingwithcancer:Aroleforthegp130receptorandexercise.July2014 ExperimentalBiologyMeeting,AmericanPhysiologicalSociety,Invitedspeaker,SanDiegoCA.EEP symposiumMolecularMechanismsofMuscleAtrophy,title“Il-6&MuscleRemodelingwithCancer Cachexia.April2014. JohnsonCSmithUniversity,Biochemistry/ChemistrySeminarSeries,CharlotteNC,InvitedSpeaker. “ColonCancerResearchattheUniversityofSouthCarolina”March2014. COBRECenterforDietarySupplements&InflammationSeminarSeries,USCSchoolofMedicine, ColumbiaSC.InvitedSpeaker.“Quercetinsupplementationandthepreventionofgutbarrier dysfunctionduringcancercachexia”.March2014 2013 TexasTechUniversity,ExerciseandSportsScienceDepartment,LubbockTX,InvitedSpeaker.“Theregulationof proteinturnoverwithcancercachexia,:Aroleforexercise”,November2013. 32 PresbyterianCollegeBiologySeminarSeries,ClintonSC,InvitedSpeaker.“ImprovingCancerPatientSurvival: UnderstandingCachexia’srole”September2013. YorkUniversityKinesiologyprogram,TorontoCanada,InvitedSpeaker.“Theregulationofproteinturnover withcancercachexia,:Aroleforthegp130receptor”,August2013. GalaxoSmithKlineMuscleResearchGroup,RaleighNC,InvitedSpeaker.“Theregulationofproteinturnover withcancercachexia:Aroleforthegp130receptor”,March2013. TheOhioStateUniversityJamesCancerCenter,CachexiaResearchGroupSeminarSeries,ColumbusOhio, InvitedSpeaker.“Theregulationofproteinturnoverwithcancercachexia,:Aroleforthegp130receptor”, March2013. 2012 MarshallUniversity,HuntingtonWVA,CellDifferentiationandDevelopmentCenterSeminarSeries InvitedSpeaker.“IL-6andcancercachexia:Aroleforexercise”March2012. AdvancesinSkeletalMuscleBiologyinHealth&Disease,UniversityofFlorida,Gainesville, InvitedSpeakerinSymposium“MuscleProteinTurnoverWithCachexia:Aroleforexerciseandcontraction. February2012 SoutheasternChapterofAmericanCollegeofSportsMedicineMeeting.JacksonvilleFLInvitedSpeakerina symposium“GutBarrierfunctioninApcMinmice”February2012 KansasUniversity,HealthSportandExerciseScienceDepartmentSeminarProgram,Lawrence,KSInvited Speaker.“IL-6andcancercachexia”January2012 2011 LouisianaStateUniversity,ExerciseScienceDepartment,SeminarProgram,BatonRouge,LaInvitedSpeaker.“IL6andcancercachexia”November2011 CaseWesternReserveMedicalSchool,CancerCenterSeminarProgram InvitedSpeaker.“IL-6andcancercachexia”November2011 CenterforColonCancerResearch,UniversityofSouthCarolina;ResearchRetreat,InvitedSpeaker.“GutBarrier functioninApcMinmice”January2011 2010 CenterforColonCancerResearch,UniversityofSouthCarolinaSeminar,“IL-6andCancerCachexia”Oct.2010 SyracuseUniversity,ExerciseScienceDepartmentSeminar.InvitedSpeaker.Musclewastingandcancer cachexia:TheroleofIl-6.February2010. 2009&Earlier 5thInternationalCachexiaConference,BarcelonaSpain.December2009.Invitedspeaker:Muscleregeneration withcachexia. PennStateUniversity,NollPhysiologyLab&KinesiologyDepartmentSeminarSeries.InvitedSpeaker.Muscle wastingandcancercachexia:TheroleofIl-6.October2009. UniversityofSouthCarolinaSchoolofMedicine:BiomedicalSciencesSeminarSeries,InvitedSpeaker.“Muscle wastingwithcancercachexia”March2009. CenterforColonCancerResearch,UniversityofSouthCarolina;ResearchRetreat,InvitedSpeaker.“GutBarrier DysfunctionandCancerCachexia”January2009 WestVirginiaMedicalSchool:ExerciseScienceSeminarSeries,InvitedSpeakerExerciseScienceDepartment, WestVirginiaSchoolofMedicineSpeaker.“IL-6&Wasting”November2008. AmericanCollegeofSportsMedicineNationalMeeting.IndianapolisIN.InvitedSpeakerinasymposium “WastingDiseasesinHumans:FromAnimalresearchtoClinicalApplication”andtalktitle“Hormone& CytokineInfluenceonMuscleWasting”May2008. MolecularGeneticsSeminarSeries,AnimalScienceDepartment,IowaStateUniversity.InvitedSeminarSpeaker. “IL-6&Wasting”April2007. 33 AmericanCollegeofSportsMedicineNationalMeeting.DenverCO.InvitedSpeakerinasymposium“Hormones andmuscleregeneration”.June,2006. AmericanCollegeofSportsMedicineNationalMeeting.DenverCO.ResearchPresentation“TheroleofIL-6in Overload-inducedMuscleGrowth”.June,2006 AmericanCollegeofSportsMedicineNationalMeeting.NashvilleTN.InvitedSpeakerinasymposium“Muscle wastingmechanisms”.June,2005. UniversityofSouthCarolinaCOBREColorectalCancerGroup.UniversityofSouthCarolina(Dr.FrankBerger Chair),titled“Mechanismsinducingofmusclewastingwithcancercachexia.Columbia,SouthCarolina.May 2005.InvitedSpeaker SoutheastRegionalChapterAmericanCollegeofSportsMedicine.CharlotteNC.InvitedSpeakerina symposium.Talktitle“MechanismsofMuscleWasting”.January,2005 UniversityofSouthCarolinaCOBREColorectalCancerGroup.UniversityofSouthCarolina(Dr.FrankBerger Chair),titled“ExerciseandIntestinalPolypFormationintheAPCminMouse.Columbia,SouthCarolina.April 2004.InvitedSpeaker. SouthCarolinaCancerCenter.UniversityofSouthCarolina.October2003.Invitedspeaker.Title:Exercise& APCminmousepolypformation. AmericanCollegeofSportsMedicineNationalMeeting.SanFranciscoCA.InvitedSpeaker“Immunologyand SkeletalMuscleAdaptationSymposium”.June,2003. MedicalCollegeofGeorgiaPhysiologySeminarSeries,MedicalCollegeofGeorgiaPhysiologyDepartment, November2002,InvitedSpeaker. UniversityofSouthCarolinaCOBREColorectalCancerGroup.UniversityofSouthCarolina(Dr.FrankBerger Chair),November2002.InvitedSpeaker. UniversityofSouthCarolina,BiologicalSciencesSeminarSeries.UniversityofSouthCarolina,October2002. InvitedSpeaker. UniversityofSouthCarolina,DepartmentofExerciseScienceSeminarSeries.UniversityofSouthCarolina, August2002.InvitedSpeaker. AmericanCollegeofSportsMedicineNationalMeeting.St.Louis,Missouri.InvitedSpeaker“Doseresponseof ExerciseSymposium”.June,2002. UniversityofFloridaDepartmentofExerciseScienceSeminarSeries.UniversityofFlorida,Departmentof ExerciseScience,March2001.InvitedSpeaker. UniversityofGeorgiaDepartmentofExerciseScienceSeminarSeries.UniversityofGeorgia,Departmentof ExerciseScience,March2001.InvitedSpeaker UniversityofMissouriVeterinarySciencesSeminarSeries.UniversityofMissouriVeterinarySchool,Columbia Missouri,February2001.InvitedSpeaker SoutheastRegionalChapterAmericanCollegeofSportsMedicine.RegionalMeeting,ColumbiaSC.Organizer& speakerofasymposiumentitled“Theeffectofalteredloadingonskeletalmusclegeneexpressionand function”.January27,2001 BasicSciencesBiomedicalSeminarSeries,UniversityofSouthCarolinaSchoolofMedicine,ColumbiaSC. November20,2000.InvitedSpeaker DevelopmentalBiologyWeeklyDepartmentalMeeting,UniversityofSouthCarolinaMedicalSchool,Columbia SC,October1999.InvitedSpeaker AmericanCollegeofSportsMedicineNationalMeeting.Seattle,WA.InvitedSpeaker“MolecularRegulationof AgingSymposium”.June,1999,InvitedSpeaker. 34 AmericanCollegeofSportsMedicineNationalMeeting,Denver,CO.InvitedSpeaker“TheRegulationofStriated MuscleHypertrophySymposium”.May,1997 1996AmericanPhysiologicalSocietyIntersocietyMeeting;IntegrativeBiologyofExercise.Vancouver,British Columbia.InvitedSpeaker“PlasticityofMuscleSymposium”.October,1996. DepartmentofIntegrativeBiology,Physiology,andPharmacologyIntramuralSeminarSeries.TheUniversityof TexasHealthScienceCenter,Houston.,September,1996. DepartmentofIntegrativeBiology,SummerLectureSeries.TheUniversityofTexasHealthScienceCenter, Houston.,July,1996. DepartmentofIntegrativeBiology,SummerLectureSeries.TheUniversityofTexasHealthScienceCenter, Houston.,July,1995. AmericanCollegeofSportsMedicineNationalMeeting,Minneapolis,Minn.Session“MuscleandRegulatory Mechanisms”.June,1995. DepartmentofPhysiologyandCellBiology,SummerLectureSeries.TheUniversityofTexasHealthScience Center,Houston.,June,1994. AmericanCollegeofSportsMedicineNationalMeeting,IndianapolisInd.MolecularMechanismsInterest Group.June,1994. DepartmentofCardiology,GuestPresentation.TheUniversityofTexasHealthScienceCenter,Houston,1994 DepartmentofPhysiologyandCellBiology,BrownBagPresentationSeries.TheUniversityofTexasHealth ScienceCenter,Houston,October,1993. DepartmentofExerciseScience,SeminarSeries.OhioStateUniversity,1993. DepartmentofVeterinaryAnatomyandCellBiology,GuestPresenter.TheOhioStateUniversity,1992 DepartmentofExerciseScience,SeminarSeries.OhioStateUniversity,1992. DepartmentofExerciseScience,SeminarSeries.OhioStateUniversity,1990. 35 SpeakingPresentations–Instructional/Service UniversityofSouthCarolinaNIH/IDEAmeeting,ColumbiaSC,Invited.“TheCenterforColonCancer ResearchattheUniversityofSouthCarolina:ProgressandUpdates”November2014 ColonCancerResearchGalaLuncheon,ColumbiaSC,Invited.“Thescopeofcoloncancerresearchatthe UniversityofSouthCarolina”March2014 SouthCarolinaHighSchoolStrengthCoachesAnnualMeeting,ColumbiaSC,InvitedSpeaker.“Analysis of2003-2013StrengthChampionshipData:insightsandconclusions”January2014 SouthCarolinaHighSchoolCoachesAnnualMeeting,GreenvilleSC,InvitedSeminarSpeaker. “ConditioningPitfallsrelatedtotheHighSchoolAthlete”July2010 RichlandSchoolDistrict1CoachesConvocation2009,ColumbiaSC,InvitedSeminarSpeaker.“Using Datatoevaluatemiddleschoolandhighschoolathletes:Theroleofexercisetesting”.August14,2009. SouthCarolinaHighSchoolCoachesAnnualMeeting,CharlestonSC,InvitedSeminarSpeaker.“Exercise Physiology&Training”July2009. SouthCarolinaHighSchoolCoachesAnnualMeeting,CharlestonSC,InvitedSeminarSpeaker.“Exercise Physiology&Training”July2008. SouthCarolinaChapteroftheNationalStrength&ConditioningAssociationAnnualClinic,Universityof SouthCarolina,InvitedSeminarSpeaker.“AdaptationstoResistanceExercise”April2008. SouthCarolinaHighSchoolCoachesAnnualMeeting,CharlestonSC,InvitedSeminarSpeaker.“Core training”July2007. SouthCarolinaAthleticTrainersAssociationAnnualMeeting,ColumbiaSC,InvitedSeminarSpeaker. “Inflammation:FriendorFoe”July2007. SouthCarolinaChapteroftheNationalStrength&ConditioningAssociationAnnualClinic.Universityof SouthCarolina.InvitedSpeaker.Title“MuscleHypertrophy:Whathavewelearned?”May2007 SouthCarolinaChapteroftheNationalStrength&ConditioningAssociationAnnualClinic.Charleston SouthernUniversity,March2006.InvitedSpeaker.Title“FunctionalTesting:Whatcanittellus?”. SouthCarolinaChapteroftheNationalStrength&ConditioningAssociationAnnualClinic.Charleston SouthernUniversity,May2005.InvitedSpeaker.Title“MuscleHypertrophywithResistanceTraining”. TridentAnnualSportsMedicineConference.Charleston,SouthCarolina,June2004.InvitedSpeaker. Title“FemaleResistanceTraining;Whatmodulatestheresponse? SouthCarolinaChapteroftheNationalStrength&ConditioningAssociationAnnualClinic.Charleston SouthernUniversity,June2004.InvitedSpeaker.Title“ErgogenicAidsandmusclemasschangeswith resistanceExercise. SouthCarolinaChapteroftheNationalStrength&ConditioningAssociationAnnualClinic.Universityof SouthCarolina,June2003.InvitedSpeaker.Title“Femaleadaptationstoresistancetraining. SouthCarolinaChapteroftheNationalStrength&ConditioningAssociationAnnualClinic.Universityof SouthCarolina,Columbia,June2002.InvitedSpeaker.Title“Youthadaptationtoresistancetraining”. 36 Teaching TeachingAwards • • NominatedfortheArnoldSchoolofPublicHealthKeithTeachingAward,2004,2009, 2012,2013. NominatedfortheUniversityofSouthCarolinaKeyAwardforIntegrating UndergraduateTeachingandResearch,Spring2007. LastPeerReviewofteachingevaluationSpring2014,Ratingof5(outof5),excellentrating RecentStudentevaluationsforcoursesentirelytaughtbyJCarson Course EXSC880Myology(3h) EXSC781ExercisePhysiology2(3h) EXSC695WritinginResearch(3h) EXSC755:SkmMuscleOverload EXSC223A&P1(3h) EXSC781ExercisePhysiology2(3h) EXSC695WritinginResearch(3h) EXSC880Myology(3h) EXSC223A&P1(3h) RecentCoursesTaught Sum2015 Spring2015 Fall2014 Sum2014 Sum2014 Spring2014 Spring2014 Sum2013 Sum2013 N 5/7 9/13 10/15 5/10 21 7/10 10/11 12 33 Universitywide(5high) 4.4–4.8 4.44–4.67 4.6-4.8 4.6–5.0 4.45-4.73 4.79 4.54 4.74 4.49 Effectiveness(5high) 4.60 4.56 4.50 4.75 4.73 4.86 4.70 4.67 4.06 Fall2015(1courserelease,chairduties) EXSC777 ExerciseandEndocrineFunction(Davis)3h,taught1lectureonanabolichormones EXSC783 ExerciseScienceSeminarseries1h(N=13),coordinatelectureseminarseriesfordepartment EXSC899 DissertationPreparation6totalcredithours,1-3h(N=5),7htotal HNRS499 SeniorThesis/Project(N=1,3h) Summer2015 EXSC790 Graduateindependentstudy,3h(N=1),graduateresearchexperience(3credithtotal) EXSC880 Myology,3h(N=7),coordinateandtaughtentirecourse EXSC899 DissertationPreparation6totalcredithours,1-2h(N=5) Spring2015 EXSC781 AdvancedExercisePhysiologyII,3h(N=13),coordinateandteachentirecourse EXSC783 ExerciseScienceSeminarseries1h(N=13),coordinatelectureseminarseriesfordepartment EXSC899 DissertationPreparation11totalcredithours,1-4h,N=4 Fall2014 EXSC695 WritingandPresentinginResearch,3h(N=15),coordinateandteachentirecourse EXSC783 ExerciseScienceSeminarseries1h(N=21),coordinatelectureseminarseriesfordepartment EXSC899 DissertationPreparation2totalcredithours,1h(N=2) Summer2014 EXSC223 Anatomy&PhysiologyI,4h(N=21),coordinatelabsandtaughtalllectures EXSC755 Skeletalmusclewithaginganddisease,3h(N=12),coordinateandtaughtentirecourse EXSC785 AdvancedExercisePhysiologyLab,3h(N=2),coordinateandtaughtentirecourse EXSC790 Graduateindependentstudy,3h(N=1),graduateresearchexperience(3credithtotal) EXSC899 DissertationPreparation5totalcredithours,1-2h(N=4) Spring2014 BMEN499 CollegeEngr,BiomedicalEngrUndergraduateResearch(N=1) EXSC695 WritingandPresentinginResearch,3h(N=12),coordinateandteachentirecourse EXSC781 AdvancedExercisePhysiologyII,3h(N=10),coordinateandteachentirecourse EXSC783 ExerciseScienceSeminarseries1h(N=13),coordinatelectureseminarseriesfordepartment EXSC799 ThesisPreparation,6h(N=1),MSthesis EXSC899 DissertationPreparation11totalcredithours,1-4h,N=4 Fall2013 SCHA499 SeniorThesis,3h(N=3),undergraduateseniorthesis(6htotal) EXSC499 UndergraduateIndependentstudy,3h,(N=1)laboratoryresearchexperience EXSC695 WritingandPresentinginResearch,3h(N=4),coordinateandteachentirecourse EXSC783 ExerciseScienceSeminarseries1h(N=20),coordinatelectureseminarseriesfordepartment 37 EXSC780 EXSC777 EXSC790 EXSC798 EXSC799 EXSC899 Summer2013 BIOL399 EXSC223 EXSC785 EXSC790 EXSC799 EXSC880 EXSC899 Spring2013 SCHC390Z EXSC499 EXSC695 EXSC781 EXSC783 EXSC790 EXSC799 EXSC899 Fall2012 EXSC780 EXSC777 EXSC783 EXSC899 Summer2012 EXSC223 EXSC785 EXSC790 EXSC899 Spring2012 EXSC499 EXSC695 EXSC783 EXSC798 EXSC899 Fall2011 EXSC780 EXSC777 EXSC783 EXSC799 EXSC899 GraduateExercisePhysiology(Durstine)3h,taught25%ofcourse ExerciseandEndocrineFunction(Davis)3h,taught11.5hlectureonanabolichormones MechanismsofPhysicalactivityHealthRelationship(Pate)1h,taught11hlectureoncancer GraduateProject,3h(N=1),MSproject ThesisPreparation,6h(N=1),MSthesis DissertationPreparation11totalcredithours,1-4h,N=4 UndergraduateIndependentStudy,3h(N=1) Anatomy&PhysiologyI,4h(N=39),coordinatelabsandtaughtalllectures AdvancedExercisePhysiologyLab,3h(N=2),coordinateandtaughtentirecourse Graduateindependentstudy,3h(N=1),graduateresearchexperience(3credithtotal) ThesisPreparation,3h(N=1),MSthesis Myology,3h(N=12),coordinateandtaughtentirecourse DissertationPreparation5totalcredithours,1-2h(N=4) HonorsCollegeproject,1h(N=1) UndergraduateIndependentstudy,3h,(N=1)laboratoryresearchexperience WritingandPresentinginResearch3h(N=4),coordinateandteachentirecourse AdvancedExercisePhysiologyII,3h(N=12),coordinateandteachentirecourse ExerciseScienceSeminarseries1h(N=14),coordinatelectureseminarseriesfordepartment Graduateindependentstudy,1-2h(N=3),graduateresearchexperience(4credithtotal) ThesisPreparation,4h(N=1),MSthesis DissertationPreparation8totalcredithours,1-3h,N=4 GraduateExercisePhysiology,3h(N=29),taughtentirecourse ExerciseandEndocrineFunction(Davis)3h,taught1lectureonanabolichormones ExerciseScienceSeminarseries1h(N=17),coordinatelectureseminarseriesfordepartment DissertationPreparation6totalcredithours,1-3h(N=3) Anatomy&PhysiologyI,4hcourse,taughtentirecourse(N=27students) AdvancedExerciseScienceLab,3hcourse,taughtentirecourse(N=6students) GraduateIndependentStudy,3h,supervised(N=1students) DissertationPreparation2h-4h,supervised(N=5students) UndergraduateIndependentstudy,3h,(N=1)laboratoryresearchexperience WritingandPresentinginResearch3h(N=2),coordinateandteachentirecourse ExerciseScienceSeminarseries1h(N=21),coordinatelectureseminarseriesfordepartment GraduateProject,3h(N=1),MSproject DissertationPreparation13totalcredithours,1-6h(N=5) GraduateExercisePhysiology,3h(N=40),taughtentirecourse ExerciseandEndocrineFunction(Davis)3h,taught1lectureonanabolichormones ExerciseScienceSeminarseries1h(N=22),coordinatelectureseminarseriesfordepartment ThesisPreparation,3h(N=1),MSthesis DissertationPreparation19totalcredithours,1-6h(N=5) 38 Coursesdevelopedorsignificantlymodifiedasfarascontentandrequirementsby JamesCarson. EXSC781AdvancedExercisePhysiology2,UniversityofSouthCarolina,Columbia. 2013–Present.DesignedcoursetocoveradvancedExercisePhysiologytopics. EXSC695“ReadingandWritinginResearch”,UniversityofSouthCarolina,Columbia. Spring2003-Present.Iserveasthemaininstructorforanundergraduateandgraduateexercisesciencemajors.The courseisaseniorlevelresearchanddesigncourse.Topicsincludebasicresearchdesign,dataanalysis,proposalwriting, practicalresearchexperienceandresearchpresentation. SCCC376C“SkeletalMuscleActivity&DiseasePrevention”,UniversityofSouthCarolina,Columbia. IwasaskedbytheSouthCarolinaHonorsCollegetodevelopandteachanHonorsCollegecoursethatwouldbotheducate andstimulatecuriosityintobiologicalresearch,Themainobjectivesrelatedtothiscoursearetoteachthescientific researchprocesswhilelearningtherelationshipofskeletalmuscleactivitywithvariousphysiologicalconditionsrelatedto disease. EXSC783“ResearchSeminarinExerciseScience”,attheUniversityofSouthCarolina,Columbia. Coursedesignedtoteachthecomponents,andformationprocessofascientificproposal.Componentscoveredincluded introduction,specificaims,literaturereview,andmethodology.Taught100%ofthecourse. EXSC780“AdvancedExercisePhysiologyI”,attheUniversityofSouthCarolina,Columbia. Fall1999-2005&2007-presentThefirstinaseriesofrequiredgraduatelevelcoursesforexercisesciencemasters,DPT andPh.D.students.Iteach100%ofthecourse,whichisrelatedtotopicsencompassingadvancedexercisephysiology relatedtocardio-respiratoryandskeletalmusclefitness. EXSC785“AdvancedExercisePhysiologyLab”,attheUniversityofSouthCarolina,Columbia. Summer2000-present.Arequiredcourseforthesis/researchtrackgraduatestudents.Thecoursecombines theorybasedlecturewithpracticallabexperience.Assaystaughtincludeproteinquantification,enzyme activity,westernblotting,andplasmidDNAisolation. EXSC755C“SpecialTopicsinExerciseScience”,attheUniversityofSouthCarolina,Columbia. Sum2000–2005,2014 Thisseriesofcourseswasdesignedbymyselftoexpandthestudent’sknowledgeofthephysiologicaladaptationstoskeletalmuscle byreadingandsynthesizingcurrentandclassicresearchinspecifictopicareas.Thiscourseisdesignedtoprovideanalysisthatis moreindepththanwhatiscurrentlyprovidedinthecoreexercisesciencecurriculum. Topics: 2000:SkeletalMuscleAdaptationtoResistanceExerciseinYouth,AdultandAgedPopulations. 2001:MuscleMassMaintenance/HypertrophyDuringWastingandDisuse. 2002AgingandSkeletalMuscle. 2003Skeletalmuscleandhormones. 2004Morphologicalandfunctionaladaptationstoresistancetraining. 2005Cellularmechanismsofmusclegrowth 2014Skeletalmuscleadaptationtoresistancetrainingandoverloadwithaginganddisease(ORTAD) EXSC880“Myology”attheUniversityofSouthCarolinaColumbia. AdoctorallevelcourseforAppliedPhysiologytractstudents.Thiscourseprovidesanindepthexaminationofskeletal muscleadaptationtoexerciseandtraining. PhysiologyfortheHealthSciencesattheUniversityofSouthCarolinaSchoolofMedicine,Columbia. Spring2000-2002.Itaughtthemusclephysiologyportionofthiscoursedesignedforallhealthsciencegraduatestudentsat theUniversityofSouthCarolina.ThecourseisofferedthroughthePhysiologyandPharmacologyDepartmentatthe UniversityofSouthCarolinaSchoolofMedicine. 39 Service:University UniversityFacultyAthleticsRepresentative(FAR)SearchCommittee,AppointedbyProvostOffice, Fall2013. UniversityCommitteeonTenureandPromotion(UCTP).ELECTED,3yearterm.Serveonfaculty reviewpanels,andreviewandpresentfacultyfilestothefullcommittee.2013–2014(resignedto becomeDepartmentChair) FacultyadvisorforExerciseScienceClubStudentOrganization.2013–present University Athletics Advisory Committee. ELECTED, 3 year term. University-wide committee to advisetheFacultySenateonUniversityAthleticmatters.2013–2016. Integrated Biomedical Sciences Graduate Program Steering Committee. Appointed. Universitywide committee to facilitate graduate student recruitment and retention in the Integrated BiomedicalGraduateProgramattheUniversityofSouthCarolina.2010–Present AnimalCareUsersGroup.Appointed.NewUniversity-widecommitteetoexamineissuesrelatedto animalresearchontheSouthCarolinacampus.2010–Present. Faculty advisor for South Carolina Club Football Student Organization. 2010 – 2014. (Club disbanded) JudgefortheJuniorScience&HumanitiesSymposium.2010,2011,2012,2013 Writtenevaluationofhighschoolsciencepapersforthecompetition. HeadJudgeJr.DivisionGeneralScience,AnnualUSCCentralSouthCarolinaRegionIIScienceand EngineeringFairattheCarolinaColiseum,ColumbiaSouthCarolina.2010 Institutional Animal Use and Care Committee, University of South Carolina, University President appointedfullcommitteemember.Monthlyyearroundmeetingwhereallanimaluseprotocolsto be performed at the University of South Carolina are reviewed and approved or rejected. 2001 - 2009. HeadJudgeSr.DivisionGeneralScience,AnnualUSCCentralSouthCarolinaRegionIIScienceand EngineeringFairattheCarolinaColiseum,ColumbiaSouthCarolina.2007–2009 JudgeGraduateStudentDayCompetition,April,UniversityofSouthCarolina2007,20082011 AppointedtoUniversity-wideSearchCommitteeforHeadVeterinarianattheUniversityofSouth Carolina2006–2007. ScienceFairJudge,GeneralScienceCategory,AnnualUSCCentralSouthCarolinaRegionIIScience andEngineeringFairattheCarolinaColiseum,ColumbiaSouthCarolina.2003,2004,2005,2006, 2007 UniversityofSouthCarolinaFacultySenate.AppointedfacultysenatorrepresentingtheSchoolof Public Health and the Department of Exercise Science. Monthly meetings to discuss and vote on issuespertainingtothegovernanceoftheUniversityofSouthCarolina.2002–2004. Institutional Animal Use and Care Committee, University of South Carolina, University President appointedalternate.Monthlyyearroundmeetingwhereallanimaluseprotocolstobeperformed attheUniversityofSouthCarolinaarereviewedandapprovedorrejected.2000-2001. 40 Service:ArnoldSchoolofPublicHealth SearchCommitteeMemberClusterHireinPhysicalActivity2011 DirectorPhysicalActivityResearchTaskForce(futuredirections)2010–2012 CEPHCertificationCommittee,ArnoldSchoolofPublicHealth2009–2010 ResearchAdvisoryCommittee.ArnoldSchoolofPublicHealth2007-Present ASPHCouncilofGraduateDirectors,ArnoldSchoolofPublicHealth2007-Present GraduateStudentAwardsCommittee,ArnoldSchoolofPublicHealth2007-Present Tenure&PromotionCommittee,ArnoldSchoolofPublicHealth2005–Present ResearchFacultyReviewCommittee,SchoolofPublicHealth2005-2007 CEPHCommitteeforCriteria,SchoolofPublicHealth2000–2001 GrievanceCommittee,SchoolofPublicHealth2000–2002 HumanSubjectResearchApprovalCommitteeSchoolofPublicHealth.2001-2002 Service:DepartmentofExerciseScience MemberSearchCommitteeforEXSCChair,2013–May2014. MemberSearchCommitteefor2EXSCfacultypositions,2013–present ChairClusterSearchCommitteeExerciseScience2012-2013 DirectoroftheWeeklyExerciseScienceDepartmentSeminarSeries2002–present DirectorofGraduateStudies2007–present UndergraduateAdvisoryCommittee2010–Present SearchcommitteeMC/Rtenuretrackfacultysearch2011–2012 IntegrativeMuscleBiologyJournalClub,weekly2001–present DirectorAppliedPhysiologyDivision,2004–2008 Co-DirectorofScientificFoundationsUndergraduateTrack,2001–2010 ChairSearchCommittee,ExerciseSciencetenuretrackAssistantProfessor2007–2008 SearchCommitteeMember,ExerciseSciencetenuretrackAssistantProfessor2006-2007 ExerciseScienceGraduateCommittee2001–2005 ExerciseScienceLaboratoryEquipmentSafetyCourse1999–2006 IntegrativeMuscleBiologylaboratoryMeeting,weekly1999-present FacultyMeetings,ScienceDepartment1999–present UndergraduateCommittee,1999–2001 ExerciseScienceStudentLaboratoryRiskManagementGroup,1999–2000 Service:Professional 41 BoardTrusteeMember,SouthEastChapterofAmericanCollegeofSportsMedicine,elected 2014-2016 NominatedandranforACSMBoardofTrusteeselection(notelected).2013 ElectedExercisePhysiologyCouncilor,Environmental&ExerciseSection,AmericanPhysiological Society.Term2012-2015 EditorialBoard,ExerciseSportsScienceReviews(ESSR),AmericanCollegeofSportsMedicine. 2011–2014 AmericanCollegeofSportsMedicineScienceIntegration&LeadershipCommittee.2009–2012 AmericanCollegeofSportsMedicineResearchAdvisoryCommittee.2006–2009 SouthCarolinaStateChapteroftheNationalStrengthandConditioningAssociation(NSCA) Secretary,andClinicDirector,2001-2008 HelpedestablishSouthCarolinaChapteroftheNSCAandcurrentlyholdSecretary positionontheexecutiveboard.Alsoset-up,organized,andadministeredtheannual stateclinicinJunefor2002,2003&2004.The2002&2003clinicswereheldinthe ExerciseScienceDepartmentatTheUniversityofSouthCarolina,Columbia.The2004 clinicisbeingheldatCharlestonSouthernUniversity.Theorganizationandannual clinichassteadilygrownoverthe3yearsithasbeeninexistence. Professionalmemberships(current) AmericanCollegeofSportsMedicine AmericanPhysiologicalSociety NationalStrengthandConditioningAssociation Manuscriptreview 2013–present EditorialBoard,JournalofAppliedPhysiology 2009–present EditorialBoard,AmericanJournalofPhysiologyIntegrative&Regulatory 2011–2014 AssociateEditor,Exercise&SportsScienceReviews 1999–2003 EditorialBoard,JournalofAppliedPhysiology. Manuscriptsreviewedfor: JournalofAppliedPhysiology AmericanJournalofPhysiology(CellPhysiology,Endocrine&Metabolism) PLOSJournals Nature:CellBiology MedicineScienceSportsandExercise JournalofNeuroscienceMethods LifeSciences InternationalJournalofSportsMedicine Grantreview 2105 2014 2014 2013–Present 2013 2012 NIH/NCITumorCellBiologyexternalreviewer,June NIH/NCIProvocativeQuestions:CancerTherapy&Outcomesgrantreview NIHSMEPstudysectionexternalreviewer,June VeteransAffairsCellular&MolecularMedicinePanelMember NIH/NCIProvocativeQuestions:CancerTherapy&Outcomesgrantreview NASAGrantReviewPanel:MuscleStudySection 42 2012 2011 2011 2007 2003-2005 VeteransAffairsCellular&MolecularMedicinePanelAdHocreview AdHocreviewWorldCancerResearchFund(WCRF)researchgrant ExternalreviewerFrenchMuscularDystrophyAssociation(AFM)GrantReview NSFAdHocproposalreview. MidAtlanticAmericanHeartAssociationGrantReviewCommittee StudySection:Mid-Atlantic5-MolecularSignaling) TraveltoBaltimoreinAprilfor2-daysandreviewAHAapplications related tomolecularsignaling.Servedasprimaryreviewer,secondary reviewer,andvoting committeememberonapproximately60proposals. Willserveuntil2005. Service:Community 2007–2010 SouthCarolinaUnitedFutbalClub,SouthCarolina’slargestcommunitybased,nonprofit,youthsoccerclub.Iservedasanadvisortocoachesanddirectorsonconditioningand maturationissues.Includein-serviceactivities. 2008–2010 ElectedBoardmember,IrmoHighSchoolYellowJacketClub,fundraisingarmforall IrmoHighSchoolathletics. 2003-2005Richland–LexingtonPublicSchoolDistrict5–appointedhealthprofessionalonpanelto examinesexeducationpoliciesandcurriculumdelivery.2003-2005 2007-2012 HeadJudgeSouthCarolinaHighSchoolStrengthandConditioningStateChampionships 2007–Present HeadJudgeHighSchoolRegionStrengthandConditioningChampionshipsheld atByrnesHighSchoolandWoodruffHighSchool 1999–present.Providedcoaches,playersandparentswithfreeadvice,demonstrationsandhandouts regardingconditioning.Routinely(manyyears)workwithandtestmaleandfemalehighschoolsoccer athletesforcoachesasrequestedforPhilSavitz(IrmoHigh,RiverBluffHigh),MikeMauldin(Dutch ForkHigh,BlythewoodHigh)Thisservicecontinuestobeprovidedatnocharge,lastperformed January2014. 2004BenLippenHighSchoolJVFootballDefensiveCoordinator 2005BenLippenHighSchoolVarsityFootballDefensivelinecoach 43 Certifications • • • • CertifiedOlympicLiftingClubCoach,USAWeightlifting,2002 CertifiedStrengthandConditioningSpecialist(C.S.C.S.),NationalStrengthandConditioning Association(N.S.C.A.)(1992,expired). ClassDlicensedyouthsoccercoachthroughU.S.SoccerAssociation,2000. NationalYouthSoccerCoachingDiploma,NationalSoccerCoachesAssociationofAmerica2001. 44 References • • • • • LarryDurstine,Ph.D. Professor Chair,DepartmentofExerciseScience UniversityofSouthCarolina 1300WheatStreet Ph:(803)777-7680 Fax:(803)777-8422 E-mail:ldurstin@mailbox.sc.edu GregHand,Ph.D..MPH Professor&Dean SchoolofPublicHealth RobertC.ByrdHealthSciencesCenter WestVirginiaUniversity Ph:(304)293-9190 E-mail:gahand@hsc.wvu.edu StephenAlway,Ph.D. Professor Chair,DivisionofExercisePhysiology WestVirginiaSchoolofMedicine P.O.Box9227 Morgantown,WestVirginia9227 E-mail:salway@hsc.wvu.edu JamesReecy,Ph.D. Professor Dept.AnimalScience IowaStateUniversity 2255KildeeHall AmesIowa50011 jreecy@iastate.edu Ph:515-294-9269 45