TG119 Test Suite for VMAT The Duke Experience The Delivery Systems for RapidArc Fang-Fang Yin, Ryan McMahon, Jennifer O’Daniel, Jackie Wu • Objectives – Understand clinical feasibility of using TG119 test suite for RapidArc commissioning and QA Varian 21EX 120 Millennium MLC Static and Rotational IMRT Static gantry IMRT RapidArc/VMAT NovalisTx 120 HD MLC Acceptance Testing and Commissioning One of the important component for VMAT acceptance testing and commissioning is to perform an end-to-end test for the process of VMAT, including simulation, planning, QA, localization and delivery. TG119 useful for evaluating planning, QA, and delivery Multiple apertures At each angle One aperture At each angle 1 TG119 Test Suite and RapidArc: Initial Observations and Experience • All TG119 tests are compatible with RapidArc delivery – Planning constraints met in all test cases – Phantom geometries for chamber and film measurements pose no problem – Measurements only done for composite dose distributions Currently, we are only evaluating the test suite using single arc treatment plans with full 360o gantry rotations Comparison of Planning Results TG119 Test Suite for RapidArc Treatment Planning • Arc arrangements will depend on your clinic’s preferences • We used single arcs with full gantry rotations, • Our intent is to re-evaluate if we want to start using multiple arc plans and/or partial gantry rotations. • All TG119 planning constraints achievable with single– arc RapidArc plans • Doing Static Gantry IMRT plans in parallel with RapidArc plans gives you an initial understanding of the advantages or disadvantages of each technique. Comparison of Planning Results Prostate MultiTarget 6000 Duke IMRT NTx Duke IMRT 21Ex TG119 Results Duke IMRT NTx 9000 Duke IMRT 21Ex 8000 Duke RapidArc NTx Duke RapidArc 21Ex Duke RapidArc NTx 7000 Duke RapidArc 21Ex 4000 6000 Dose (cGy) D ose (cG y) 5000 TG119 Results 3000 2000 5000 4000 3000 1000 2000 0 CentralTarget CentralTarget D99 D10 Superior Target D99 Superior Target D10 Inferior Target Inferior Target D99 D10 1000 0 Prostate D95 Prostate D5 Rectum D30 Rectum D10 Bladder D30 Bladder D10 2 Comparison of Planning Results Head & Neck Comparison of Planning Results TG119 Results C-Shape Easy Duke IMRT NTx Duke IMRT 21Ex 6000 Duke IMRT 21Ex 6000 5000 4000 4000 Duke RapidArc 21Ex 3000 2000 2000 1000 1000 0 0 PTV D90 PTV D99 PTV D20 Cord Maximum Parotid D50 Comparison of Planning Results C-Shape Hard Duke IMRT 21Ex Duke RapidArc NTx 6000 PTV D95 PTV D10 Core D10 Acceptance Testing Sample TG119 Results Duke IMRT NTx 7000 Duke RapidArc 21Ex • Test 2.1: Accuracy of dMLC position vs. gantry position – Tolerance: + 1 mm • Test 2.2: Accuracy of dMLC position during arc 5000 Dose (cGy) Duke RapidArc NTx 5000 Dose (cGy) Dose (cGy) Duke RapidArc 21Ex 3000 TG119 Results Duke IMRT NTx Duke RapidArc NTx 4000 – Tolerance: + 1 mm 3000 • Test 2.3: Ability to accurately detect MLC position error 2000 – Criteria: detect sub-millimeter error in position 1000 0 PTV D95 PTV D10 Core D10 3 Acceptance Testing Sample Commissioning RapidArc Delivery • Next perform several iterations of patient specific QA. • Test 2.4: Accuracy of dose rate and gantry speed control during RapidArc – Tolerance: + 2% • Our procedure was: • Ion chamber measurement in rectangular phantom • Three film planes in solid water • Axial, sagittal, coronal through high dose (PTV) • Test 2.5: Ability to control leaf speed/position during RapidArc – Tolerance: + 2% • TG119 procedure is: • Ion chamber measurements in rectangular phantom • Two film planes in solid water • Coronal plane through high dose (PTV) • Coronal plane through low dose (organ-at-risk) TG119 Test Suite for RapidArc Ion Chamber Measurements No modification required. Chamber measurements done with Ion Chambe r High Dose Re gion same phantom/chamber for fixed-beam IMRT and RapidArc TG119 IMRT vs. RapidArc: Planar Dose measurements Current TG119 results include a wide range of standard IMRT QA tools for planar dose/fluence verification 4 TG119 Results Error (% relative to prescription) 3 Duke IMRT NTx Duke RapidArc NTx 2 Local Confidence Interval: 3.1% (IMRT), 5.2% (RapidArc) 1 0 -1 Diode/Chamber Array -2 -3 TG119 Confidence Interval 4.5% -4 -5 Multi Target Prostate Head & Neck C-Easy C-Hard Film EPID These can be used for initial RapidArc/VMAT commissioning, but many clinics will have new devices for rotational IMRT QA. 4 How to Incorporate New Rotational QA Devices into the Test Suite? Angular Dependence of Planar Measurement Devices • Response of planar measurement devices can have a substantial angular dependence. – Potentially large source of uncertainty, particularly for treatment plans containing partial arcs • Solutions: – Fix QA device to gantry (e.g. EPID) • Potential to miss gantry position errors – Angular calibration/correction Delta 4 • Not currently available for some commercial QA devices Matrixx Sun Nuclear TG119 Test Suite for RapidArc Multi-planar Measurements Coronal Plane (Film) TG119 Test Suite for RapidArc Multi-planar Measurements Sagittal Plane (Film) 5 Remaining Issues, Future Directions • Evaluate test suite using plans with: • Partial arcs • Multiple arcs • Design phantom geometries and planning conditions that are more applicable to delivery with a rotating gantry • Organize multi-institutional analysis of the test suite’s application to RapidArc/VMAT • Build upon initial TG119 results • How to deal with large variations between commercially available VMAT QA devices 6