Overview of Digital Detector Technology J. Anthony Seibert, Ph.D. Department of Radiology University of California, Davis Disclosure • Member (uncompensated) – BarcoBarco-Voxar Medical Advisory Board – ALARA (CR manufacturer) Advisory Board Learning Objectives • Describe digital versus screenscreen-film acquisition • Introduce digital detector technologies • Compare cassette and cassettecassette-less operation in terms of resolution, efficiency, noise • Describe new acquisition & processing techniques • Discuss PACS/RIS interfaces and features 1 Conventional screen/film detector 1. Acquisition, Display, Archiving Transmitted xx-rays through patient Film processor Exposed film Developer Fixer Wash Dry Gray Scale encoded on film Intensifying Screens Film x-rays → light Digital xx-ray detector 2. Display Digital to Analog Conversion Digital Pixel Matrix 1. Acquisition Transmitted xx-rays through patient Digital processing Analog to Digital Conversion Charge collection device X-ray converter x-rays → electrons 3. Archiving Analog versus Digital Spatial Resolution MTF of pixel aperture (DEL) 1 100 µm Modulation 0.8 200 µm 0.6 1000 µm 0.4 0.2 0 0 1 2 3 4 5 6 7 8 9 10 11 Frequency (lp/mm) Sampling Pitch Detector Element, “DEL” DEL” 2 Characteristic Curve: Response of screen/film vs. digital detectors 5 Useless 10,000 FilmFilm-screen (400 speed) Digital 1,000 3 2 Overexposed Useless 100 Correctly exposed 1 10 Relative intensity Film Optical Density 4 Underexposed 0 0.01 20000 0.1 1 10 100 1 Exposure, mR 2000 200 20 2 Sensitivity (S) Analog versus digital detectors • Analog – – – – Coupled acquisition and display Higher resolution Limited dynamic range, fixed detector contrast Immediate exposure feedback • Digital – – – – Separated acquisition and display Lower resolution Higher dynamic range and noisenoise-limited contrast Proper exposure potentially hidden Image Processing • Crucial for optimal image presentation • Flexibility adds potential advantage – DiseaseDisease-specific image processing – Computer aided detection 3 Digital System Technologies Projection Radiography • Computed Radiography (CR) • CCD “Direct” Radiography (DR) • CMOS • Flat Panel (TFT) arrays Consideration: “Cassette” Cassette” vs. “Cassetteless” Cassetteless” operation Computed Radiography (CR) ...is the generic term applied to an imaging system comprised of: Photostimulable Storage Phosphor to acquire the xx-ray projection image CR Reader to extract the electronic latent image Digital electronics to convert the signals to digital form Image Acquisition CR QC Workstation Patient information Latent image produced CR Reader Latent image extracted DICOM / PACS Laser film printer Display / Archive 4 CR: Photostimulated Luminescence τ phonon Conduction band tunneling τ recombination Energy Band BaFBr 4f 6 5d Laser stimulation F/F+ e- PSL 3.0 eV 8.3 eV 2.0 eV τ Eu 4f 7 / Eu 3+ Eu 2+ e Incident x-rays Valence band PSLC complexes (F centers) are created in numbers proportional to incident xx-ray intensity CR: Latent Image Readout Reference detector f -θ lens Cylindrical mirror Light channeling guide Laser Source Output Signal Polygonal Mirror ADC PMT Laser beam: Scan direction x= 1279 image y=To1333 z=processor 500 Plate translation: SubSub-scan direction Phosphor Plate Cycle PSP x-ray exposure Base support plate exposure: create latent image reuse laser beam scan plate readout: extract latent image light erasure plate erasure: remove residual signal 5 CR Innovations • HighHigh-speed line scan systems (<10 sec) • DualDual-side readout capabilities (increase DQE) • Structured phosphors • Mammography applications ?? • Low cost tabletable-top CR readers DR: “Direct” Direct” Radiography ....refers to the acquisition and capture of the x-ray image without user intervention – “Indirect” Indirect” detector: a conversion of xx-rays into light and then light into photoelectrons – “Direct” Direct” detector: a conversion of xx-rays to electronelectron-hole pairs with direct signal capture CCD detector systems • Area Scintillator / lens coupling CCD Scintillating Screen (Gd2O2S), CsI • Area Scintillator / fiberoptical coupling Scintillating Screen (CsI) Array of CCD Fiber Optical Cameras Coupling • Slot scintillator linear array fiberoptical coupling 6 CCD area detector 35 cm High fill factor ~ 100 % Good light conversion efficiency (~85%) 5 cm 5 cm 43 cm 2.5 cm 2.5 cm 4 to 16 megapixels Optical de-magnification Lens efficiency? Secondary Quantum Sink Optically coupled CCD systems • Technology improvements are overcoming quantum sink issues (lens / phosphor) • Low cost systems for budgetbudget-limited situations • Capable imaging systems Scanning slot chest xx-ray system • • • • • CCD array Fiberoptic coupling No grid Reduced scatter Low dose • “Effective” Effective” DQE compares to flatflat-panel systems 7 CMOS • “RAM” RAM” with photodiode converter • Random access readout • Low voltage operation (5V) • ? NOISE …… • Large FOV detector available (tiled CMOS) CMOS DECODER LATCHES COUNTER ROW DRIVERS Complementary Metal Oxide Semiconductor PIXEL ARRAY COLUMN SIGNAL CONDITIONING CLK RUN DEFAULT LOAD ADDRESS DATA +5V DECODER TIMING AND CONTROL COUNTER VS_OUT VR_OUT READ FRAME LATCHES Array of tiled CMOS sensors Xrays Scintillator Fiberoptic plate Microlens optics CMOS sensors Controller electronics 7000x7000 element array, 17” 17” x 17” 17” FOV for one implementation 8 ThinThin-FilmFilm-Transistor Array Laptop LCD display PhotoPhoto-emitter X-ray converter Photo detector TFT Active Matrix Array TFT active matrix array Amplifiers – Signal out G1 Active Area G2 Dead Zone G3 D1 Data lines CR1 D2 CR2 D3 CR3 Gate switches ThinThin-Film Transistor Storage Capacitor Charge Collector Electrode Charge Amplifiers Analog to Digital Converters ThinThin-FilmFilm-Transistor Array • Indirect (CsI scintillator + photodiode) • Direct (a (a-selenium) 9 Indirect / Direct flat panel detector systems FlatFlat-panel Fluoroscopy / Fluorography • Based upon TFT charge storage and readout technology • ThinThin-FilmFilm-Transistor arrays – Proven with radiography applications – Now available in fluoroscopy • CsI scintillator systems (indirect conversion) • a-Se systems (direct conversion) Flat panel vs. Image Intensifier Flat panel II Field coverage / size advantage to flat panel Image distortion advantage to flat panel 10 Flat vs. Fat Digital Flat Panel Conventional II Dynamic Range Very Wide (5-10 times more than conventional) Narrow (TV camera limit) Distortion No Distortion Distortion from curved input surface of II Detector Size Weight and thickness much lower Heavy, bulky detector Image Area 41 cm x 41 cm square Round area is more than 20% smaller area for same diameter Image Quality Good resolution, high DQE Good resolution, high DQE Dynamic range Digital Flat Panel II/TV Saturation Limit <Soft Tissue> <Spine> Saturation Limit Video Signal Detector Signal <Lung> Noise Floor Noise Floor X-Ray Intensity X-Ray Intensity Flat panel vs. Image Intensifier • Electronic noise limits flatflat-panel amplification gain at fluoro levels (1(1-5 µr/frame) • Pixel binning (2x2, 3x3) offers improvements • Low noise TFT’ TFT’s are slowly being produced; variable gain technologies on the horizon • II’ II’s will likely go the way of the CRT…… CRT…….. 11 Detector Characteristics • MTF • NPS • DQE ““Pre-sampled” PrePre-sampled” sampled” MTF 1.0 0.9 a-Selenium: 0.13 mm 0.8 Modulation 0.7 0.6 CR: 0.05 mm 0.5 0.4 ScreenScreen-film 0.3 CsICsI-TFT: 0.20 mm 0.2 0.1 CR: 0.10 mm 0.0 0.0 0.5 1.0 1.5 2.0 2.5 3.0 3.5 4.0 4.5 5.0 Frequency (lp/mm) Detective Quantum Efficiency, Radiography 0.8 DQE( f ) CsI - TFT 0.6 a-Se - TFT 0.4 CR “dual-side” Screen-film 0.2 CR Conventional 0.0 0.0 0.5 1.0 1.5 2.0 2.5 Spatial Frequency (cycles/mm) 12 Equipment considerations • Specific applications – Fluoroscopy – Pediatrics – Trauma and ED – Orthopedics multimulti-film studies (scoliosis, etc) – Dental panorex – Operating room – Mammography – Radiation Therapy Escape Dental Panorex example Integration into “digital” digital” paradigm often requires creative ideas, e.g., modification of cassette for CR Technological Advances CR mammography 50 µm spot Thicker phosphor layer front back Transparent phosphor base 2 light guides LineLine-scan CR array reader with “structured” structured” phosphor Portable DR Device Resurgence of “slotslot-scan” scan” systems • No grid, great scatter rejection • Low patient dose CR systems with DR form factor 13 Pros and Cons: CR vs. DR • CR • DR – Flexibility* Flexibility* – Single room use • portables, multiple rooms, mammography -- direct replacement • Dedicated chest, bucky • C-arm / UU-arm – New technology – Proven technology* • experience is expanding • 2 decades of experience – Screen-film paradigm – Acquire and display* • extra steps for processing • no extra steps • ↑ patient throughput Pros and Cons: CR vs. DR • CR • DR – Limited DQE • Higher dose for same SNR – Integration/interfacing • PACS +++ • x-ray system + – Range of systems and * costs to match needs – Higher DQE * • Better dose efficiency – Integration/interfacing * • PACS +++ • x-ray system +++ – Higher costs for detector and xx-ray source $$$ Escape Less distinction between CR / DR “cassette” cassette” vs “cassetteless” cassetteless” Portable Lower cost CR Portability Flexibility Low cost DR Speed Ease of use High cost Integrated High speed 14 Advanced Acquisition & Processing Techniques • Dual energy imaging – Tissue selective imaging – Differential attenuation with energy • Digital tomosynthesis – Acquisition from several projection angles – Reconstruction of tomographic slices Dual Energy Image Pair Low kVp High kVp ? Nodule? TissueTissue-selective Images Soft – tissue Only Nodule not in soft tissue image Bone Only → Nodule calcified 15 Digital Tomosynthesis: reduce structured noise Left Right Shift images to select plane Add to create tomogram • 3 cm above detector • 9 views, + to - 30° • 1.4 x dose Tomographic ramp Niklason, L.T. et.al. Radiology 205:399-406 QC tools, phantoms, exposure data • Consider systems with a simple yet robust QC phantom and automated analysis • Look for a system having exposure information with database mining capabilities • Find out about preventive maintenance and unscheduled maintenance procedures • Provide for adequate quality control support!! • QC Workshop: Wednesday, Room 608 Escape CR / DR Implementation • PACS and DICOM – Digital Imaging COmmunications in Medicine – Provides standard for modality interfaces, storage/retrieval, and print • Modality Worklist (from RIS via HLHL-7 “broker” broker”) – Reduce technologist input errors • Technologist QC Workstation – Image manipulation and processing – “For Processing” Processing” vs “For Presentation” Presentation” – VOI LUT 16 CR/DR implementation • Robust PACS/Network System – Image Size: Storage Needs • 8 - 32 Mbytes uncompressed – 10 Pixels/mm – 4300 x 3560 x 2 Bytes • 3 - 13 Mbytes: 2.5:1 Lossless Compression • Lossy compression??? – Network Transmission • 100 Mbit/sec Mbit/sec minimum (diagnostic workstations) CR/DR implementation • Uniformity Among CR/DR images and Display Monitors – Acceptance Testing • Measurement of Performance • Correction of Substandard Performance – Calibration of CR/DR Response – Calibration of Monitors • Maximum brightness • LookLook-upup-Tables, DICOM GSDF, Part 14 – Heterogeneous environment more difficult… difficult…. IHE? Conclusions • CR is the most flexible and costcost-effective technology for digital acquisition • Direct digital radiographic devices have advantages in efficiency and throughput • RealReal-time imaging & advanced processing are clinically relevant considerations 17