Ultrasound Beamformation and Image Reconstruction AAPM 2009 Conference G. Wayne Moore, B.Sc., MA, FASE What we will cover • Historical Perspective of Ultrasound Technology • Ultrasound and Tissue Water • Partition of Ultrasonic Imaging Events • Image Quality Advances • Ultrasound System Architecture Changes • Beamformation Analysis and Test Device • Modern Approaches to Solving Old Imaging Problems • Newer Approaches to Image Reconstruction – 2D Matrix Arrays • Test Fixture and 3D Volumetric Image Reconstruction Analysis • What’s Coming in the Future for Ultrasound We’ Water””! We’re Just “Bags of Water Ultrasound and Tissue Water • An archetypal person has about 40 L of body fluid • 25 L are inside 75 trillion cells • 15 L are outside the cells (interstitial spaces) • 5 L in blood volume – 2 L of RBCs – 3 L of plasma Still the law! 1540m/sec 6.5B 6.5 Bsec/cm 1 Partition of Ultrasonic Imaging Events The scanhead or Transducer History of Modern Diagnostic Ultrasound Transmit signal out Echo signal return 2 Specialized Signal Processing Gray Scale Image Processing 1 TissueTissueultrasound Doppler Image Processing 3 6 In co mp lex ≅t ity Color/Gray scale display Mass Storage: VCR CD 5 PACS LAN 4 1979 2009 •A-Mode •M-Mode •B-Scan •Mechanically Steered Real-time •Linear Array Real-time •Zero-crossing Doppler •Spectral Doppler (FFT) •Phased Array Real-time •CW Doppler in Probe – Bernoulli Equation •Color Flow Doppler •Triplex modes of Operation •Pseudo-Color •Color “Angio” & Power Doppler •Harmonic Imaging & Variants •Contrast Media Imaging •Spatial Compounding •3D Imaging – Volumetric •4D Imaging – Steered Curved Array •Phase Aberration Correction 3D Volumetric cardiac image derived from 2D Matrix Array with 2,500 elements pseudo Color display identifies proximal and distal echoes Some 3D Clinical Advantages: Advantages 1985 1997 No geometric assumptions No mental interpolations (cognitive reconstruction) Provides pre-surgical perspective Provides post-surgical perspective Pyramidal volume of ultrasonic data 2 + Evolution of Ultrasound System Architecture Proprietary Hardware Centric Design Proprietary Hardware Centric Hybrid Centric Proprietary Software Centric Software + Generalized Backend Centric Single Platform Microsoft XP Embedded Software Platform Specialized Front End Generalized Back End Proprietary Software Centric Design TGC Application The digital beamformer function has historically resided in the main console of the ultrasound system Shift from analog to digital beamformers PA ADC PA ADC PA ADC PA ADC PA ADC PA ADC PA ADC PA ADC PA ADC 128 Element Transducer PA = Pre amplifier ADC = Analog to digital converter Dynamic Time Delays Change of System Technologies Since 1990 = Σ 10 bits 36 MHz 1024 Values 60 dB Dynamic Range 3 Digital beamforming 2009 Higher element counts were once restricted by the need to have a single wire in the probe cable for each element in the array. Multiplexing the elements allowed for transducers with higher element counts and a lower number of transmit channels in the beamformer. Current 2D matrix arrays with element counts of 2,500 necessitated a different approach to beamforming, and where the beamforming, or at least parts of it would take place. Beamformation Analysis Text--fixture and setText set-up High speed serial interface that provides control signals for the sub-beamformer e.g., defining delays for each unique element x Sub-beamforming performed in the probe x (f) x(f) x(f) 100 Channels feeding & receiving 2,500 elements Would be normally what a “standard” front end would expect to see Time sampling is digital, all else is analog Commercially available ultrasound probe and system testing device using a single crystal to both receive signals from the probe and transmit signals into the system via the probe. 4 Green LED Red LED Fundamental Imaging sample rate gaps in phased array sector display Test Device – Block Diagram Power On Timer 200 mSec ON OFF Threshold timer 10 mSec Amplifier Comparator Transducer + Threshold Level Target 3-5 cm 5-7 cm 7-9 cm 10MHz 3-5cm 5MHz 5-7cm 26µsec = 2cm 26µsec = 2cm 2nd Harmonic Imaging Harmonic Image Fundamental Image Generator 10 MHz 5 MHz 2.5 MHz Target Transmitter 2.5MHz 7-9cm 26µsec = 2cm An example of expanding aperture focusing used to maintain spatial resolution throughout depth of field Active aperture changes as a function of depth 5 Old imaging problems, new imaging approaches Transducer Scanning Field Shadowing Object Shadow Still the law! 1540m/sec 6.5B 6.5 Bsec/cm Objects that are very reflective or very attenuating remove ultrasound from the image area behind the mass producing shadows. These events mark a specific interaction between ultrasound and tissues, and a property of the shadowing tissues. Shadowing in Propagation Events Probe Transducer Scanning Field Refractive Surface Refractive Shadow Circular or cystic structures can produce refraction at the edge of the structure, bending the beam into the object, producing shadows extending from the edge of the object. This happens with a change in propagation velocity, but does not happen if there are no velocity changes. Ultrasound Refraction at the Edge of a Circular Object Breast Lesion Normal Scan Lines SonoCT Scan Lines Spatial Compounding 6 Limited Fields of View Spatial Compounding Using Multiple Apertures and Angles SieScape by Siemens Slice Motion With a structure identifying algorithm, the system locates and positions major structures, calculating the structure location in the continuous slicing scan of the transducer. This technique is equivalent to compound B-scanning without a scanning arm. 7 Complex Beamforming in 4D Systems 20 Degree Angle Text--fixture and setText set-up for 4D Image Formation Analysis Using a Philips iE33 Ultrasound System and X7X7-2t probe In order to create “real-time” 4D ultrasound images (i.e., three spatial dimensions plus motion), volume datasets must be acquired, processed and displayed at a rate higher than the capacity of the human eye to retain a visual impression 60 Degree Angle Bench SetSet-up Nickel (PVDF) Tektronix Scope RF Power Amplifier Probe/Nickel Fixture 2D Matrix Array 2,500 elements Frame rate paces random access to the array 8 TEE/Nickel Interface Position/Pressure Control Mechanism 3 2 3 2 1 2 3 2 3 X7-2t 5x5 element sub-aperture Philips X7-2t probe 2500 elements 100 channels Inside the X7X7-2t Potted Passive Components Array Carrier CCD X7--2t Inside the X7 Flex to Array Interface Flex Circuit Backing Material Gold Foil I/O connection for Integrated Circuit Tip Collar Coax to Flex Circuit Interface Transducer Array NonNon-insulated Bm thick bonding wires* 9 System Interface Input signal from Nickel 4Bsec burst @ 5MHz * common mode rejection ratio Battery powered Diff PrePre-amplifier good high freq detection and CMRR* Detecting xmit, generates target, gets amplified by the RF amp Ultrasound system pulse Noise feed through from RF amp Nickel pulse Noise + Acoustic Acoustic signal only Receive out of ultrasound system Nickel transmit pulse matches every other system transmit creating one line gaps in sector display shown above 10 3D image rotated Nickel transmit pulse displayed across all slices ½ sector switching 3D image Nickel transmit pulse displayed Ni Sys Ni Sys Signal In Front Mixed mode (Color Flow Doppler and Imaging) Reduced frame rate approximately matches every Nickel pulse thereby “filling in” each sector line 11 Signal In Middle So What is Coming Next? Signal In Back Major innovation in ultrasound will slow, but… 12 …ultrasound still must remain competitive with other so… … advanced imaging modalities such as MR, so (1) 2D Matrix Arrays will be developed for broader clinical application For example, extensions of ultrasound applications based on clinical need and cost effectiveness Standard Imaging System Connector Standard Ultrasound Cable (2) Design and optimization of capacitive micro-machined ultrasonic transducers – silicon substrates may not be the avenue 1. Wrist-Mounted Connector (3) Extended sub-beamformer + CMUTs 2. Flat Flex Cable 3. Small-profile, finger-mounted array END PRESENTATION Thank You Nobility of Soul Never Kept a Business in the Black 13