Meiosis notes Dec 8-16 December 16, 2014 Meiosis- producing half of DNA to pass on to offspring = Gametes ↳ sperm or egg Meiosis notes Dec 8-16 December 16, 2014 2 stages 1. Meiosis I (unique) Prophase I--> Metaphase I --> Anaphase I --> Telophase I 2. Meiosis II (exactly like mitosis but with 1/2 the chromosomes) Prophase II--> Metaphase II --> Anaphase II --> Telophase II Meiosis notes Dec 8-16 December 16, 2014 Meiosis I Prophase I - ~ 90% of the time of meiosis a. chromosomes condense and coil up b. nuclear membrane dissolves c. crossing over occurs between non-sister homologous chromosomes (synapsis) - homologous chromosomes. wrap around each other and exchange genetic material. Meiosis notes Dec 8-16 December 16, 2014 -unique mixture of DNA from both parents that you can no longer tell if chromosome is from mom or dad Purpose for crossing over -increases genetic diversity beyond independent assortment of chromosomes Meiosis notes Dec 8-16 December 16, 2014 Metaphase I -homologous chromosomes stay paired up and line up side by side along metaphase plate - each centromere has only ONE Kinetochore (not 2) -centrioles produced spindle fibers but only grab one homologous chromosome Meiosis notes Dec 8-16 December 16, 2014 3. Anaphase I - Homologous chromosomes are separated - sister chromosomes are still connected at centromere 4. Telophase I --> chromosomes at opposite poles - nuclear mebrane reforms - chromosomes unwind Cytokinesis- cell splits into two new cells * Not functional Meiosis notes Dec 8-16 December 16, 2014 Meiosis II- exactly like mitosis but with 1/2 of the chromosomes. n=2 here the cells will finish with only n =haploid Meiosis notes Dec 8-16 December 16, 2014 5. Prophase II -chromosomes condense - nuclear membrane dissolves - centrioles move to opposite poles n=3 still * Exactly like prophase of mitosis Meiosis notes Dec 8-16 December 16, 2014 - chromosomes at opposite poles of cell -nuclear membrane reformes -chromosomes uncoil Cytokinesis- all cells separate and contain only n which is haploid (not 2n like mitosis) Meiosis notes Dec 8-16 December 16, 2014 Oogenesis- the formation of the egg 1 cell --> 1 supersized egg and 2 polar bodies Spermatogenesis- formation of the sperm 1 cell--> 4 sperm