CT Basics Dianna Cody, Ph.D. Professor & Chief, Radiologic Physics U.T. M.D. Anderson Cancer Center “Pure” CT • Information regarding attenuation correction with CT AND • Information regarding how CT is partnered with PET • Will be covered later in the workshop Axial Platforms first generation Axial/Helical Platforms second generation 1 CT X-ray Tube Design Evacuated glass or metal envelope Oil for insulation and heat dissipation Lead housing absorbs unwanted x-rays Port for useful beam Beam Collimation • Pre-patient collimators define width of beam in z (all systems) • “Detector” collimators reduce scatter at detectors (some CTs) X-ray Beam Characteristics • Polyenergetic beam – Bremsstrahlung radiation – Characteristic Ch i i radiation • Max photon energy depends on kVp • Min photon energy depends on filtration Beam Filtration • Removes low energy x-rays from beam – Low E photons contrib to dose, not image – Filter reduces beam-hardening artifacts • Shapes energy distribution across beam – Removes more low energy from edges – Results in more uniform beam hardening after passing through filter and patient 2 Beam Filtration Detector Characteristics X-ray fan beam Filter Shaped beam Patient • • • • • Efficiency Response time Dynamic range High reproducibility Electronic stability Uniform output Solid State Detectors Image Reconstruction Process Back Projection – 1st Generation CT Object = Rod in air • Photodiode multipliers (no PMT) • CdWO4 crystals 99% conversion and capture efficiency • Ceramics 99% absorption, 3X conversion Beam direction black arrow 1 (angle 1) Tube detector scans across Tube-detector (red arrows) Data (Profile 1) recorded w/ detector position Repeat for Angle 2 to get Profile 2, etc 3 Backprojection Reconstruction Filters 1 Object 2 Projection data 1 2 3 Recon filter 3 4 4 Backprojection of filtered data 5 Backprojection of filtered data for two angles Filtered Backprojection Filtered profile 5 Filtered Backprojection 4 Spatial Resolution X-Y Voxel Size Ability to detect a small object easily distinguished from background • • • • • • • Display Field of View (DFOV) size Reconstruction filter (algorithm, kernel) X-rayy tube focal spot p size Image thickness (blurs edges of objects) Pitch (blurs edges of objects) Patient motion Image zoom Voxel size = DFOV/512 512 pixels 50 cm DFOV Pixel = ~ 1 mm 512 pixels Effects of Recon Filters on Resolution & Noise Std Recon Soft Recon Effects of Recon Filters on Resolution & Noise Std Recon Bone Recon 5 Effects of Recon Filters on Resolution & Noise Std Recon Effects of Recon Filters on Resolution & Noise Detail Recon Std Recon Edge Recon Contrast Resolution Ability to see a small object not easily distinguished from background (NOISE) Effects of Recon Filters on Noise Recon Filter Soft Standard Lung Detail Bone Edge Bone Plus Std Dev Water Img 3.8 4.7 19.6 6.5 18.8 35.8 27.0 • Effective mAs mA * time / pitch • • • • Image thickness Patient size Reconstruction filter Viewing conditions 6 ACR Phantom - Low Contrast Section Viewing Conditions - Contrast • Distance • Ambient (room) lighting – Cannot see the stars in the daytime • • • • 120 kVp, 1600 mAs Monitor brightness Reflections Viewing angle (flat screens) [Age of eyeballs…] 120 kVp, 192 mAs Pixels and Image Matrices Pixels and Image Matrices 222 220 200 146 103 200 158 127 96 73 207 131 103 82 86 202 126 112 124 133 Pixel Values (HU) 7 Typical CT Numbers CT Number • Pixel bit-depth of 212 = 4096 values • Contrast scale HU = Constant (µm – µwater) / µwater – CT number for water = 0 at all energies – CT number range –1024 to +3072 • CT number affected by kVp – Reduce kVp, increase contrast Select CT#’s with WW WL • • • • • • • • -1024 Air ~ -700 Lung ~ - 120 to ~ -80 Fat Water 0 +/- 5 Brain ~ 40 Soft Tissue ~ 40 to ~ 100 200 to > 600 Bone Metal > 1000 Slip-ring 8 Pitch for Single-Slice CT • Image and beam width are same for conventional CT • Pitch = table travel ÷ beam width Conventional Helical CT Detectors Image width determined by beam thickness Pitch = table mm / beam mm • Typical pitch values are 0.7 to 1.5 Pitch Imagine a CT Scanner with a spray paint can in place of the x-ray tube. z Pitch Definition • Pitch = distance table travels width of x-ray beam • Pitch = distance table travels width of spray paint 9 Pitch Helical Interpolation Collect data (black dots) Rebin to estimate the 180° data (blue squares) I t Interpolate l t to t estimate ti t image between collected and rebinned data Helical CT needs fast computers MSCT detectors Multi-Detector Concept 64 x 0.625 mm • • • • Acquisition of multiple images per scan Electronic post-patient collimation Faster volume acquisition times Better bolus tracking and thin slices for 3D z 1.25 mm General Electric 4 & 64 & 16 channel detectors 10 Channels (or data channels) Detector Configuration detector 4 x 1.25 mm 4 x 2.5 mm 11 4 x 5 mm channel channel channel channel 4 x 3.75 mm MSCT Detectors z z MSCT Detectors Image width determined by output channel Pitch = table mm / beam mm z Pitch = table mm / n * T where n = no. of channels and T = channel thickness z THIRD Gen. 12 MSCT Faster Scanning Detector # rotations 1 x 1.25 Beam Thick. (mm) 1.25 160 Total scan time (sec) 128 4 x 1.25 5 40 32 8 x 1.25 10 20 16 16 x 1.25 20 10 8 64 x .625 40 5 4 1.25mm images and 20cm scan length at 0.8sec rotation and 1.0 pitch Ring Artifact Artifact Sources • Scanner – Detector imbalance – Obstruction of beam – Pitch and detector configuration • Patient – Motion – Implants (dental, prosthetics, etc.) – Non-uniformity of normal “ingredients” 16-slice CT 3rd generation and MSCT Detector imbalance 0.625mm image Axial acquisition 16 x 0.625 Material in beam IV contrast ‘gunk’ factor Image number 7 of group with 16 images 13 16-slice CT 16-slice CT Axial acquisition Axial acquisition Image number 8 of group with 16 images Image number 9 of group with 16 images Multislice CT Recall Helical Interpolation Collect data (black dots) • Helical non-planar data • Data from multiple channels Rebin (blue squares) Interpolate for image 2nd rotation 1st rotation 1 2 3 4 1 2 3 4 Longitudinal direction 00 complementary data 1800 direct data 3600 14 MSCT Ring Artifact • Imbalance of detector causes ring in those axial images that are same width as detector element 16-slice CT 0.625mm image Helical scan 16 x 0.625 • Images from “binned” detector elements may not show h ring i • Helical MSCT images have arc instead of ring Pitch = 0.562 Image number 5 of group with 16 images • Arc artifact might not show in images thicker than the element size (depends on pitch and recon alg) Helical scan Helical scan Image number 6 of group with 16 images Image number 7 of group with 16 images 15 Helical scan Image number 8 of group with 16 images MSCT Arc Artifact 16-slice CT 1.25mm image • Might not be visible in each image due to overlying anatomy • Easiest to find when viewing images in “stack” mode • Lower pitch, longer arc • Visibility affected also by WW/WL Pitch = 1.375 (16 x 0.625) Position of arc inferred from other images in series Visibility depends on local anatomy 16 Arc visible, but faint Arc visible, but faint 17 Helical or Windmill Artifact MSCT Helical Artifact • Occurs at high subject contrast interface – – – – Bone and soft tissue (ribs, skull) Air and soft tissue Air and Ba contrast i.v. contrast in tubing • Varies with – Angle of interface w.r.t. scan plane – Pitch and image width (combined) High-contrast objects at angle to scan plane Reducing Helical Artifact • Increase z-axis sampling • Change pitch, if possible • Change detector configuration, if possible • For Prospective study with thin retros – check all image thicknesses at several pitches (scan a phantom) – choose optimal pitch for all desired image thicknesses 18 Prospective images at 5mm Scanner: 16-channel Same as patient study Pitch: 0.875, Detector: 8×2.5mm, Beam: 20mm Detector: 8 x 2.5 Pitch = 0.875 SE 2, IM 2, 5mm SE 3, IM 3, 2.5mm Retrospective images at 2.5mm Change detector (incr. Z sampling), retain beam width Z-axis Sampling Summary Pitch: 1.375, Detector: 16×1.25mm, Beam: 20mm Effective mAs = 109 (decreased from 171) SE 10, IM 2, 5mm SE 11, IM 3, 2.5mm • In general, use smallest detector spacing possible! • More powerful than decreasing pitch to reduce helical artifacts • Beam width may change with detector configuration • Changes in beam width and/or pitch will affect total scan acquisition time 19 End • Please score this section on evaluation sheet. sheet • Thanks!! 20