Drugs and Our Society Drugs and the Brain Part 6 The Nervous System 1. The nervous system can be divided into two parts: 2. 3. - the peripheral nervous system (PNS) and - the central nervous system (CNS) The peripheral is made up of the somatic nervous system and the autonomic systems Somatic nervous system - nerve cells that interact with the external environment - consciousness / voluntary reactions - it is made up of sensory nerves (eyes / ears / skin / tongue (vision / hearing / touch / taste) Nervous System, cont - sends sensory information to the CNS - pinch your skin / speck of dust in the eye - sends movement information back out - twitch of the arm / blink or tearing of eye 4. Autonomic nervous system - internal environment is monitored and controlled - operates the visceral (involuntary) body functions - it is an unconscious reaction - heart rate / blood pressure / breathing Nervous system, cont 6. Central nervous system - consists of the brain and spinal cord - spinal cord functions primarily as a relay station - it transmits information from sensory nerves to the brain - it carries motor commands from the brain to the muscles 7. The brain - it is a complicated structure - made up of nuclei and fiber tracts Nervous system, cont - it contains 100 billion neurons - these are the messengers in the brain - they transmit information via chemical and electrical processes - they are considered neurotransmitters, such as serotonin / dopamine / nor epinephrine 8. It is capable of storing and analyzing more information than today’s supercomputers - it is not as fast, but can deal simultaneously with 1000’s of pieces of input Nervous system, cont 9. The brain has a rich supply of blood from 4 major arteries - drugs circulating in the blood have a fast access to the brain 10.Blood-brain barrier - capillaries in the brain are different - the cells are tightly joined - this keeps many drugs from reaching the brain 11.For a drug to be psychoactive, the molecules must be capable of passing this barrier Nervous system, cont 12.Drugs are carried to the brain by the blood supply - how do they know where to go - they don’t - drugs go everywhere 13.Certain drugs impact certain neuron cells - LSD acts on serotonin in the brain - where the psychoactive drugs are similar to the molecular structure of neuron chemicals - the drug molecules interact with the brain chemistry Parts of the Brain 1. There are 3 primary parts to the brain: - the forebrain / midbrain / hindbrain 2. Hindbrain - controls breathing / heart rate (respiration) / and digestion - it is highly sensitive to opiates / alcohol / barbiturates / and depressants 3. Midbrain - sensory and motor reflexes - processing of pain information Parts of the brain, cont 4. Forebrain - feeding / drinking / sexual behavior - organizing emotional behavior - visual / auditory / sensory 5. The brain is further broken-down into the: - cortex - medulla oblongata - hippocampus, and - thalmus