Units of Measurement and Conversions Course Practicum in Health SciencePharmacology Rationale Basic math principles are important in providing quality client care when pharmaceuticals are involved and knowledge of various measurement systems is essential in proper dosage calculation for client safety. Unit VII Career Preparation and Employability Objectives Upon completion of this lesson, the student will be able to: Know the measurement systems associated with pharmacology Perform the mathematical processes related to pharmacology Apply concepts of measurement functions in multiple-step conversion problems Convert between measurement systems to calculate drug dosages Essential Question Why is having a good math skill important in the Health care field? Engage A physician orders a medication that is given according to a patient’s weight. Give 1mg/kg to your patient. Your patient weighs 154 lbs. How much does he weigh in kg, and how much medication will you give. TEKS 130.205(c) 1A, 2A, 2B, 7A Key Points I. The apothecary system – based on 12-ounce pound A. Officially replaced by metric system B. Standard unit of measure for weight (solid substances) is the grain (gr) Prior Student Learning Basic math skills Estimated time 3 - 5 hours C. Liquid volumes (fluids) are measured by minim D. Rarely used today II. Common household system A. Less accurate system of measurement B. Primarily used by patients who take medication at home C. Practitioner’s responsibility to assure consumer is taking correct dose D. Necessary for practitioner to know equivalents from “pharmacy language” to every day common household terms E. Conversions 1. Standard teaspoon established to contain approximately 5 ml 2. 60 gtt. (gtt. = drops) = 1 teaspoonful 3. 3 teaspoons = 1 tablespoon 4. 1 teaspoon = approximately 5 Gm or g (gram) 5. 1 teaspoon = approximately 60 gr (gr = grain; not to be confused with g = gram) Copyright © Texas Education Agency, 2013. All rights reserved. III. Metric system – most commonly used system in measurement, easy to use since based on parts and multiples of 10 A. Official system of measure for pharmacy practice B. Advantages 1. simple 2. brief 3. adaptable 4. universal C. Metric measures for 1. length 2. area 3. volume 4. weight 5. temperature D. Pharmacy mainly concerned with weights and volumes of drugs E. Decimal system that can be divided into any parts that are multiple of 10 (10, 100, 1000, etc.) F. Greek and Latin prefixes indicate what multiple is used, e.g. milli-, centi-, deci-, micro-, kilo-, etc. G. Standard unit of metric measure for capacity or volume is liter H. Standard unit of measure for weight is gram I. May encounter physician’s orders or prescriptions requiring conversion 1. Within same system (e.g., convert 0.350 Gm to 350 mg – quantities both metric but using milligrams may be more convenient) 2. From one system to another (e.g., 170 pounds to 77 kilograms because most drugs dosage requirements are determined by body weight in kg) 3. Translation from one system to another or within the same system is called conversion 4. Most physicians not cognizant of the various existing systems and may write orders that appear to be jumbled quantities J. Liquid drug preparations 1. Creams and ointments are expressed as percentage concentrations 2. A certain quantity of the drug is contained in the final quantity of the product a. 1 % hydrocortisone cream contains 1 g of hydrocortisone in 100 g final product (the actual drug plus the cream) b. 5% sodium chloride solution contains 5 g sodium chloride in 100 ml final product ( NaCl and distilled water) Copyright © Texas Education Agency, 2013. All rights reserved. c. 1 gram in 100 grams or 1/100 equal to 0.01, or 1% d. 5 grams in 100 milliliters equal to 5/100 or 0.05, or 5% Activity I. Complete Practice Problems II. Complete Unit Equivalency Practice III. Complete Dosage Calculations IV. Review actual prescriptions, physician’s hospital orders, and /or bulk drug manufacturing requests that require decimals, ratio/proportion, and percentage calculations. Discuss, in small groups, the various systems used for drug calculations, determining preferences and justifying why. V. Complete the Salt Hand and Foot Scrub Activity Assessment Successful completion calculation problems Materials Practice problem handouts Actual prescriptions and/or physician’s orders for medications (can be obtained from your physician or copies from hospital charts as long as information identifying patient and institution have been sufficiently obliterated – check with hospital administration if needed!) Conversion charts Salt Hand and Foot Scrub Activity Epsom Salts, Baking Soda or Brown Sugar, Salt / Sea Salt, vegetable oil, and essential oils / food flavoring oils Parchment paper or copier paper cut in appropriate size for students to collect each ingredient 1 or 2 digital scales to weigh Household measuring cups and spoons – enough for stations Plastic or glass containers large enough to hold enough ingredients for a class period Disposable foam or other type of bowls Disposable spoons Glass mortars & pestles -- enough for groups or stations Containers – individual 1 cup containers or old baby food jars with lids Label Curling ribbon Optional -- disposable plastic ice cream spoons or baby food spoons – for scooping scrub Copyright © Texas Education Agency, 2013. All rights reserved. Accommodations for Learning Differences For reinforcement, the student will review math conversation and complete the coherent sequence pretest. For enrichment, the student will develop health care related word and conversion problems directed to middle school mathematics. Include teaching aids to reinforce the relationship between measurements. National and State Education Standards National Healthcare Foundation Standards and Accountability Criteria Foundation Standard 1: Academic Foundation Healthcare professionals will know the academic subject matter required for proficiency within their area. They will use this knowledge as needed in their role. The following accountability criteria are considered essential for students in a health science program of study. 1.3 Medical Mathematics 1.31 Apply mathematical computations related to healthcare procedures (metric and household, conversions and measurements). 1.32 Analyze diagrams, charts, graphs, and tables to interpret healthcare results. 1.33 Record time using the 24-hour clock. TEKS §130.205 (C)(1)(A) interpret data from various sources in formulating conclusions; §130.205 (C)(2)(A) accurately describe and report information, according to facility policy, observations, and procedures; §130.205 (C)(2)(B) demonstrate therapeutic communication skills to provide quality care; and §130.205 (C)(7)(A) interpret knowledge and skills that are transferable among health science professions; College and Career Readiness Standards Mathematics Reasoning A. Expressions and equations 1. Explain and differentiate between expressions and equations using words such as “solve,” “evaluate,” and “simplify.” B. Manipulating expressions 1. Recognize and use algebraic (field) properties, concepts, procedures, and algorithms to combine, transform, and evaluate expressions (e.g., polynomials, radicals, rational expressions). C. Solving equations, inequalities, and systems of equations 1. Recognize and use algebraic (field) properties, concepts, procedures, and algorithms to solve equations, inequalities, and systems of linear equations. IV. Measurement Reasoning Copyright © Texas Education Agency, 2013. All rights reserved. B. Systems of measurement 1. Convert from one measurement system to another. 2. Convert within a single measurement system. VIII. Problem Solving and Reasoning A. Mathematical problem solving 1. Analyze given information. 2. Formulate a plan or strategy. 3. Determine a solution. Cross Disciplinary Standards I. Key Cognitive Skills E. Work habits 1. Work independently. 2. Work collaboratively. Copyright © Texas Education Agency, 2013. All rights reserved. MATHEMATICS CONVERSION CHART Length 1 meter = 100 centimeters 1 meter = 1000 millimeters 10 millimeters = 1 centimeter 1 inch = 2.5 centimeters Volume for Fluids 1 liter = 1000 milliliters 1 milliliter = 1 cubic centimeter 10 centiliters = 1 deciliter 10 deciliters = 1 liter 1 teaspoon = 5 milliliters 1 tablespoon = 15 milliliters 1 ounce = 30 milliliters 1 pint = 500 milliliters 1 quart = 1000 milliliters Weight Conversions 1 gram = 1000 milligrams 1 kilogram = 1000 grams 1 kilogram = 2.2 pounds 1 pound = 16 ounces Temperature Conversions Celsius to Fahrenheit (0C x 1.8) + 32 = 0F Fahrenheit to Celsius (0F – 32) ÷ 1.8 = 0C Terms and abbreviations Gram (g) measures mass or weight Liter (l) measures volume or liquid Meter (m) measures length or distance Kilo (k) = thousands Deci (d) = tenths Centi (c) = hundredths Milli (m) = thousandths Copyright © Texas Education Agency, 2013. All rights reserved. DOSE AND DOSAGES YOUNG'S RULE: Child's Dose = (Child's Age (in years)/Child's Age in Years + 12) x Adult Dose FRIED'S RULE: Infant's Dose = (Age (in months) /150 pounds) x Adult Dose CLARK'S RULE: Child's Dose = (Weight of Child (in pounds) / 150 pounds) x Adult Dose Child's Dose = (Weight of Child (in kilograms) / 68 kilograms) x Adult Dose SOLUTIONS Ratio Strength of Solutions = amount of drug / amount of solution Percent of Strength by Volume = (volume of solute/volume of solution)x100 Percent Strength by Weight (Mass) = (mass of solute/volume of solution)x100 Amount of Solute /Amount of First Solution = Amount of Solute / Amount of Second Solution BODY SURFACE AREA Used to determine drug dosage in infants and children and also used to determine the loss of body fluid in ml/hour in burn patients. Formula: BSA (m2)=0.20247 x height (m) 0.725 x weight (kg)0.425 Web site to automatically calculate BSA: http://www-users.med.cornell.edu/~spon/picu/calc/bsacalc.htm http://www.halls.md/body-surface-area/bsa.htm IV DROP RATE CALCULATION CC’S/hour x Drop Factor of the tubing divided by 60 (minutes) = drops/minute Copyright © Texas Education Agency, 2013. All rights reserved. DOSAGE CALCULATIONS EXAMPLE: Scenario: The patient is to receive 1L of Lactated Ringer’s solution continuous IV q8hr. The primary administration set delivers 15 gtts/ml. At the beginning of the shift the 1L bag is found to contain 250 ml. When checking the drip rate you find the infusion to be running at 30 gtts/min. When will the next bag be due to be hung? This problem needs to be worked in two separate steps – the first one is to determine the rate required to infuse the ordered dose over the time specified. Remember that the scenario only states what you found – you always have to double check for yourself to ascertain accuracy! Whoever started this IV before your shift may have calculated incorrectly and if you do not correct the rate you will be responsible for any undesirable results as well! 1. Find the pertinent solution required to solve the problem in the above scenario and mentally eliminate the rest. Pertinent information: 1 L/8 hrs (one entire dose); 15 gtt/ml; 30 gtt/min; 250 ml/dose (remainder from whole dose) 2. Determine what unit equivalency conversions you need. Unit equivalency conversion: 1000 ml/L; 60 min/hr 3. Determine the desired units; what is the problem asking for? Desired units: (1) gtt/min; (2) time in hr and/or min Copyright © Texas Education Agency, 2013. All rights reserved. PRACTICE PROBLEMS Solve the following problems: 1. How many cc in ½ tsp? 2. Convert 20 gtt to cc 3. How many qt in 4 fl oz? 4. Convert 1.5 inches to cm 5. Convert 0.05 g to µg 6. Convert 0.0025 L to cc 7. Convert 0.25 g to gr 8. Convert 1/40 gr to mg 9. How many tsp in 2 Tbs? 10. Convert 88 lb to kg Solve the following problems by making sure you list all the available information provided, extract the conversion factors from the information provided, and set up the conversion factors for the cancellation of the unwanted units. 1. Ordered: Furosemide 40 mg p.o. Available: Furosemide 20 mg tablets Calculate the number of tablets per dose 2. Ordered: Tylenol 500 mg p.o. stat. Available: acetaminophen 500 mg tablets Calculate the number of tablets per dose 3. Ordered: Premarin 1.25 mg PO Available: conjugated estrogens 0.625 mg tablets Calculate the number of tablets per dose 4. Ordered Procardia XL 60 mg b.i.d. Available: Procardia XL 30 mg capsules Calculate the number of capsules per dose 5. Ordered: Biaxin 500 mg po bid Available: Biaxin 250 mg tablets Calculate the number per dose Copyright © Texas Education Agency, 2013. All rights reserved. 6. Ordered: diphenhydramine 25 mg IM now Available: Benadryl 50 mg/ml in 10 ml vial Calculate the number of ml/dose 7. Ordered: Epinephrine 0.3 mg SQ stat Available: Epinephrine 1 mg/ml in 5 ml vial Calculate the number of ml per dose 8. Ordered: Fer-In-Sol 5 mg PO qd Available: Fer-In-Sol 15 mg/0.6 cc Calculate the number of ml for a 90 d supply. 9. Ordered: Phenobarbital ¼ gr PO qid Available: Phenobarbital 15 mg tablets Calculate the number of tablets/dose. 10. Ordered: Rocephin 1 g in 100 ml D5W IV b.i.d. Available: Rocephin sterile crystalline 250 mg/vial Calculate the number of vials per dose. Copyright © Texas Education Agency, 2013. All rights reserved. Answer Key: Practice Problems 1. 2.5 cc 2. 1.3 cc 3. 0.125 qt 4. 3.81 cm 5. 50,000 µg 6. 2.5 cc 7. 4.17 gr 8. 1.5 mg 9. 6 tsp 10. 40 kg Dosage Problems: 1. 40 mg/dose; 20 mg/tab; 40mg; 20 mg 2 tab/dose dose tab 2. 500 mg/dose; 500 mg/tab; 500 mg; 500 mg 1 tab/dose dose tab 3. 1.25 mg/dose; 0.625 mg/tab; 1.25 mg; 0.625mg 2 tab/dose dose tab 4. 60 mg/dose; 30 mg/cap; 2 dose/d; 60 mg; 30 mg 2 cap/dose dose cap 5. 500 mg/dose; 250 mg/tab; 2 dose/d; 500 mg; 250 mg 2 tab/dose dose tab 6. 25 mg/dose; 50 mg/ml; 10 ml/vial; 25 mg; 50 mg ½ ml/dose dose ml 7. 0.3 mg/dose; 1 mg/ml; 5 ml/vial; 0.3 mg; 1 mg 0.3 ml/dose dose ml 8. 5 mg/dose; 15 mg/0.6 cc; 1 dose/d; 90 d; 5 mg ; 15 mg 18 cc dose 0.6 ml 9. ¼ gr/dose; 15 mg tab; 4dose/d; 60 mg/gr (unit equivalence); 1 gr; 15 mg; 60 mg; 1 tab/dose 4 tab gr 10. 1 g/dose; 1 g/100 ml; 250 ml/vial; 2 dose/d; 1000 mg/g (unit equivalence); 1 g; 250 mg; 1000 mg 4 vial/dose dose vial 1g Copyright © Texas Education Agency, 2013. All rights reserved. UNIT EQUIVALENCY PRACTICE Convert the following units 1. 1 g to mg 2. 5 mg to µg 3. 0.0025 L to ml 4. 10 gr to mg 5. 68 lb to kg 6. 15 cc to tsp 7. 500 cc to L 8. 36.8o C to o F 9. 15 ml to Tbs 10. 120 µgtt to cc 11. 15 ml to gtt 12. 1 fl oz to ml 13. 2 gr to g 14. 25 cc to ml 15. 1 tsp to cc 16. 10 km to ft 17. 180 lb to kg 18. 0.0005 mg to µg 19. 500 µg to kg 20. 98.6o F to Celsius 21. 25 gr to mg 22. 1 hr to min 23. 20 kg to lb 24. 1 pt to fl oz 25. 15 gtt to µgtt 26. 1 pt to ml Copyright © Texas Education Agency, 2013. All rights reserved. ANSWER KEY TO UNIT EQUIVALENCY 1. 1 g = 1000 mg 1000 mg 2. 1 mg = 1000µg 5000 µg 3. 1000 ml = 1 L 2.5 ml 4. 60 mg = 1 gr 600 mg 5. 2.2 lb = 1 kg 30.9 kg 6. 5 cc = 1 tsp 3 tsp 7. 1000 ml = 1 L, 1 cc = 1 ml 0.5 L 8. 98.2o F 9. 5 ml = 1 tsp, 3 tsp = 1 Tbs 1 Tbs 10. 1 ml = 60 µgtt 2 cc 11. 1 ml = 15 gtt 225 gtt 12. 1 fl oz = 30 ml 30 ml 13. 1 gr = 60 mg, 1000 mg = 1 g 0.12 g 14. 1 cc = 1 ml 25 ml 15. 5 cc = 1 tsp 5 cc 16. 2.54 cm = 1 in, 12 in = 1 ft 32,808.4 ft 17. 2.2 lb = 1 kg 81.82 kg 18. 1000 µg = 1mg 0.5 µg 19. 1,000, 000 µg = 1 kg 0.0005 kg 20. 37o C 21. 60 mg = 1 gr 1500 mg 22. 60 min = 1 hr 60 min 23. 2.2 lb = 1 kg 44 lb 24. 16 fl oz = 1 pt 16 fl oz 25. 1 ml = 15 gtt, 1 ml = 60 µgtt 60 µgtt 26. 1 pt = 16 fl oz, 30 cc = 1 fl oz 480 ml Copyright © Texas Education Agency, 2013. All rights reserved. SALT HAND AND FOOT ACTIVITY – STUDENT HANDOUT 1/8 cup MgSO4 1/8 cup NaHCO3 or C12H22O11 1/8 cup NaCl 1 tablespoon C54H100O7 10 gtts essential oil or food flavoring oils ** coloring (optional) Zero the scale and weight your parchment paper. ______________ wt Zero scale with parchment paper and measure out your Salts: MgSO4 __________ NaHCO3 __________ or C12H22O11 __________ NaCl __________ Pour MgSO4 salts into a glass mortar use pestle to break down clumps and salt. Once the MgSO4 has been broken down into smaller size, place in a bowl and mix in the other ingredients and add the C54H100O7. Make sure all ingredients are well blended. Add five drops of an essential oil scent that you enjoy and blend it in well, then add five more drops and continue to blend. **Color optional – add 2 drops at a time to get desired shade Package your scrub in an airtight container and label. Create a Label with the following instructions and list the common name for the ingredients. Give your scrub a name. Instructions -- Rub scrub into hands or feet for 2 - 5 minutes. Rinse and wash with your favorite hand soap. Follow with your favorite lotion Copyright © Texas Education Agency, 2013. All rights reserved. Salt Hand and Foot Scrub Activity -- Teacher Information Materials Needed Epsom Salts, Baking Soda or Brown Sugar, Salt / Sea Salt, vegetable oil, and essential oils / food flavoring oils Parchment paper or copier paper cut in appropriate size for students to collect each ingredient 1 or 2 digital scales to weigh ingredients (may be borrowed from a science teacher or if not available you do not need to have students weigh the ingredients) Household measuring cups and spoons – enough for stations Plastic or glass containers large enough to hold enough ingredients for a class period Student Handout copies Disposable foam or other type of bowls Disposable spoons (students will use to mix ingredients) Glass mortars & pestles enough for groups or stations Containers – individual 1 cup containers or old baby food jars with lids (adjust amounts of salts/ingredients depending on container size) Label – students can create label on an index card or with computer to print Curling ribbon – students can attach their label and decorate their final product Optional -- Disposable plastic ice cream spoons or baby food spoons – for scooping scrub Put the ingredients in plastic or glass containers with the chemical names to be used in stations. You can have students in pairs or individuals – have them look up the common names on the internet. 1/8 cup Epsom Salts/ MgSO4 1/8 cup Baking Soda /NaHCO3 or Brown Sugar/ C12H22O11 1 tablespoon Salt or Sea Salt / NaCl ¼ cup Vegetable Oil / C54H100O7 10 gtts essential oil – must be safe to use on skin or you may use food flavoring oils (e.g., strawberry, coconut, banana, etc.) – must be safe to use on skin ** coloring (optional) – If you use baking soda you will be able to color the scrub. If using Brown Sugar the color will not take. Copyright © Texas Education Agency, 2013. All rights reserved. Below are the chemical names you can print to place with your ingredients. MgSO4 NaHCO3 NaCl C12H22O11 C54H100O7 Copyright © Texas Education Agency, 2013. All rights reserved.