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CHARI 1
HO~:
HO'W HO' H
AU.O-TETRAHYDRO- CORTI SOL
CORroL
TETRAHYDRO-CORTI SOL
TETRAHVDRO-CORTI SONE
P-CORTOl
CORTOLONE
,B-CORTOlONE
Ho,;F Hcr(f} Ho,iF Hoa}
M
II-KETO-
H
IIp-HYOROXY-
-ANDROSTERONE -ANDROSTERONE
H
II-I(ETO-
-ETIOCHOLANOL-ONE
H
IIP-HVDROXV-
-ETIOCHOLANOL-ONE
(1)
It
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~let'lrYJ!,'OJ.:JI
7
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5-
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THE PRINCIPAL
URINARY
METABOLITES OF S-IONONE
I
P-CAROTENE
P-IONONE
CH-C~-CH-CH
II.
o
KETONE
J
I
''a,
o
K
o
" .. II
o
Ol-KETONE
.a.. II
o
HYDROXY-KETONE
CH-CLI-C -tH
..
IE:
HYDROXY-KETONE
Cl-I-CH-C -CH
KETONE
S
OH
'
G
CH- eH-eH-eH
'
..
HO
0
,
i
I
J
,;
HYDROX¥- KETONE
C
.. I
OH
S
I
i
.I,
I
I
i
1
on
JaILANATl ON 01" FIGURES 1 -
4
Fl.un 1:
AbllOrption spectr. or Oon1801 aDd ,S-lOBODe
In plieD.11bJ'dras1_c1d (i>b/Ao) and acid eoltltloD8
Cort1_1 (SOfAg/ml.) in Pb/Ac soln•
. . -A Cort1801 (50M?!ml.) 1n Aold eoln •
• --. ,1J-Ienone (501"'g/ml.) 1n Pb/Ac 801n •
• - -. (3-1080. . (50f'g/ml.) in Ac1d _In.
A-A
~1nr.
con eo
&.-----.
e-.
• __ •
)(-x
')(- -x
ft 1nAbsorption
speotra of a 2/1 rd.%'ture or
Pb/Ac and Acid 80lut10n••
j3-!ODODe and
Cortl801 (.50",g/ml.) 1 n Pb/I.e 801ft.
;;-lonoDe (lOO,...g/ml.) in Ph/AC ••1n •
,I3-101lOu8 (100 ,Mg/ml.) in AcId 801n.
001't11101 (SOf'g/ml.) and ;3-IoDODe (If)O,..Yml.) 1n
Ph/A" eo1&.
Oortisol (50",Yml.) and ,A-IODOJle (laO t-'g/ml.) 1n
Acid 8010•
_----------" .. _.
}<"s.r."
3: Standard Cune of /.3-IonoM aDd
O. • a~405 ~ 1n acid coln •
.
• _.
x- -x
. ... -
tbe ~1,. re41totlol1 1n
IS -1oUODe
% DeeNaH in 0.,0. a-t ltD5 DIf' - pl'oponloD81 to
StaMard
~~e
QG~centr8t1onor
f--IoDODe
Absorption apectre or 00"1801 and Urine atnota.
11be. and lonone corrected.
••
Cortt.ol (30fAgllIIl.) 1n Pb/Ae 801n.
x-x
Uriu 1 I ranoM co.......ted
t!ag~1
Porte
x- -x
Urlne 1 : POl'ter-Sl1ber • •NOted
.-.
Unne 2 : lonone
.- -.
UPine 2 : Porte1'-S11'ber oorPltOte4.
001'1'80'_
FIGURE 2
FIGURE I
AITl}J
390
410
FIGURE 3
. aD.
"I" Decrease In
20
30
0'4
0.0.
0'6
10
o·a
FIGURE
o
370
"
55
( )
(
f
(
(
)
:5
:3
.3
1l"J21,
18.J 19 J
'1
1" 5,
:3
1
!~., 10
:2
"
2,
7,
\,&e i n't.~~Mi~
J'~U".:U'l.!1i!
1I
l:m:.t !Ef1:!"f'1·cultie~
to
of'
f'rOll1
tb~ t~lal ..
( s)
(
60
PL
otoac op
ith p
1
gp x cone attaob
nt.
62
2
:fitt
( )
(
)
65
P
TE
3.
Plori.11 chro eto ,rapbic col
ill t
an
(
( 1)
It
(
3
1
1)
1)1<>
(1.5 - 1.9
I
,)
were
(
)
(
FIGURE 5
CONTROL
GROUP
Southdown
.. - . - . Merino
11- - -II
Romney
..
II
EFFECTIVE BODY
WEIGHT
FEED INTAKE
Kg. r---------------~
Kg.
5S
/,.-.-.
• 1' .........
2S
/,'
• _iI
...
......../
My
g.
I
I
I
.
--
35
Jy
J
A
CLEAN DRY WOOL
PRODUCTION
.•....-.
--~-.
----'II'",.
......
"'-
....... -""""
... _CI
--
.,.,.
1.0
A
Jy
J
FIBRE DIAMETER
~5
10
2.0
My
25
'"
My
J
Jy
A
",.,..'
My
_"-'-111-'
J
Jy
_CI
A
10)
slIght
f
"
11
(
FIGURE 6
TREATED
111-111-----..
II
II
-III
EFFECTIVE BODY
WEIGHT
INTAKE
Kg.
20 l-
lS
10 I-
,II,
._--.---,/
e - .. _ . ____ . /'
/
./
..
~
Jy
J
CLEAN DRY WOOL
PRODUCTION
II
0.5
50
40
A
1.5
1.0
e--- e--
30
I
My
g.
Kg.
e
e-e--.
Southdown
Merino
Romney
11_My
,
FIBRF
Jy
II",
.~
" ....
~"D_._
11".:::.::.'.. ,-
II
'\
,\
20 ..
....
A
DIAMETER
.....
11'-::.
1 __
2S
,-
J
", ,
11_.
" _--.-.-- .
...........
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lf
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1948.
MASCBA&S. P.
8kaad. Yet. Tldu.r
Jl 278.
IOCSCHAJ;S, P.
1949. SJlllpoelum on -..-118n Germ Cella.
elba Fda. London.
MKSCHAU, P.
1953.
2, 735.
MICftELIS. A.M.
Pl"oc. 15t.h 10.t. Vet. CoDgr. Part. 1,
1962.
Eudocrin.
za.
1071.
MIOW.N. a.J., SDTRAN'D. J. t WALL. P.E., ST&MPFB.l.L, Il.S. aQ'
PRYSTOW8K.Y, H.
1957. Oolloq. hdocrln. elba ,Pdrh
11 338.
aIGBOB, C.J. ana l'LAOFl'{.
oJ. Olin.
1954.
J,. .8101. Cbem.
lULLS, I.H.
196). J. lfGc'Joarla. n .
• IXIiiR, J.P.
1951. J. Dair), Sal. JM. 4'5.
alDER, J.P. and 8AUIDEF.S, E ..L. Jr.
19528.
32 500.
zsa
767.
J. Dalr), Sci.
h.,
MIDER .. J.P., SAUIDErt8. B.L.
&0 JO. .6TO., d.E.
1957.
J. Dalr), Sci. f:Q 67.
MOD, •• F.
1958. ''lbe 8.1010£, or Hair Orowtb t •
Academic
Pr...
I
1958.
1946. Alaal~.t Z1 348.
ltliH.iIi., ft.
1958. tObl'caat.OKJ'apble YOIl at.erin_. St.ez-oldeo.
1lIl4 Ter.andt.en Verblad'wlgeu.'
~t.ercJ . . I &l ••Tler s
MORt'O., R.A. ad trrDJm8. A.L..
1~58.
NELSOlf. D.Ii. and 6.A.itUELS, L .. T •
1952.
J. Clln. KDOocrID.
11. 519.
JIOI(YUERan. J • .I.. aad STUaas, B.D.
1276.
OlUTA, a.T., K.A.8.ARA, J.J., IUC11ARDSOJI, P. and I.e ROY,
1957. aueleODlea 11 111.
a.v.
1957. J. 008ap. Path. §Z. 165.
PATIiSOli, J.T.".
1963. ,8io.b• • J. Ii P 1.
PA~iRSOB, J.T.P.
1964. J. Xndocrln. 2l 16'.
PiRU, Y. and PBRe;z, F.
1955. Ana. Endocrla. (Parla) 1.1
347.
PBTKR80lt. R.B.
1957. J. Clla. Brlcloorln. II 1150.
PIGOR, H.
1962. Acad. Poloa. Scl. Sere Bl01. 1Q. 13.
PATImSOB. J.Y.F.
.
1955.
SABA, B.
1964. .1. Badool'la." 139.
BAlfD8&'RG, F.
1949. C1t.ed b7 Holoombe, R.B., 19.53.
81'. Yet.. J. JJa .359.
1951. Di ••• Abat•• 1Z 3074.
SCHULLER,:I.
1951. Aota KnCJOCl". (I.bb) 2.5. !545.
SAROF'. J.
Kndoorlaolog7 §.g, 376.
S&&Kl.BS, L., BOlll'Z, A., aDd S.Il.ELKNBOOM. C.
19'3. Proo.
aCHILLE, s. aDd DORnAlI, A.
1957.
XVtb Int. Vet. Congr. Stookbolm. Pert 1
p
588.
8EL1'15, B.
1'37. EDcloortaoloB7 11 16,.
SHAW, 1.. •••• DtrrrA, S. and lIlCHOLS, R.E.
1960. All. J. Vet.
Re•• .21 52.
SHAW, X.S. and IfICHOLS, R.X.
1962. All. J. Vet. a.e. 2.1
1217.
SHAW, &..&. and JilCHOLS, R.B.
196,.
Am.
SHAW, I.. B. aDd 1I1CHO£S, R. s.
1964.
Jua. J. Vet.
SILBER. i..Jl. and BOSCH, R.D.
1955.
J. Clln. Bodocria.
565.
52.
505.
SILBik,
R.B. and PORTER, C.C.
923.
1954.
J. Vet..
a•••
1k,
R··.21
~
J • .Bl01. Obem. i1J2.
SIl.JliiR, R.H. aDd PO.RTl§l, c.o.
1957. Me'hode or 8loch...
Au1. '" 139.
SIMa.l, L.1., JUSUGART.
SUJ.tDWUM, L. ana JU.LliVB..A.T, A.T.
1956.
J • .Bl01. Obea. ii1 807.
SIMPSOB, S.,A., 'fAIT,
W&ftSTElJI. A., lfEB.IGR, R., YOIl jo.:Uli,
J. and RIUCHSTBIlI, 't.
1953. kperl . . tt. ~ ",.
SMITH, W.D. and WEST, B.JiI'.
1960. Acta Rheu.ll. 5eanCt. i
A.,
.1.'.,
11'.
SPURLOCK, O.M. and GLBOO, •• '1'.
(Kbb) a 205.
1960. J. Anim. Sol • .1i
SPtmLOCX, O.M. and CLEGG, M.T.
1962.
J. An1m. Sei.
1962.
Acta Endoor. (Kbb)
8PRBCHLII( t M.
1,,0.
Aot.a Endoar.
1,,6.
494.
STEINBECK, A.W. and THEILE, H.
~
n
12,.
StEAT t M.L.
1954. ADal. Cbe••
SWIBOLE. W.W. and PFIJ'lINER, J.J.
2i. 1964.
1930.
Sctence
Z1
321.
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