Innovations in Surgery 4th Quarter 2012 First annual Scott Society Lecture celebrates history of surgery W hen Sunil Geevarghese, M.D., president of the H. William Scott, Jr. Society, was planning the first Annual Scott Society Lecture he knew he had to select a speaker whose own passion for surgical care and education mirrored that of Dr. Scott. For the Executive Council of the Scott Society, it was an easy decision. Since joining the faculty in 1993, and even before as a Vanderbilt medical student, John L. Tarpley, M.D., has become synonymous with the Vanderbilt surgical residency. “What I find most remarkable about Tarp (as he is known) is not simply his prodigious love for surgical teaching, it’s the personal connection he makes with every patient, every resident,” Geevarghese said. He makes clear that his most fond ‘fourth’ child are the Vanderbilt residents.” In his presentation, Tarpley chronicled the most important scientific achievements of the last 200 years without which modern surgery would not be possible, including non-surgical technologies we now take for granted – climate control, transportation, personal computers and electricity. From these now seemingly basic amenities, five foundational discoveries in medicine laid the groundwork for 21st century surgery – anesthesia, antisepsis, imaging, blood transfusions and antibiotics. In 1846, the first of these landmark innovations was the use of inhaled ether as a form of anesthesia. The operation, performed in the Ether Dome at Massachusetts General Hospital, was of no small consequence as the surgeons were removing a carotid body tumor. The patient awoke following the surgery saying, “I don’t think I can go through with this.” News of this technique took off like wildfire and commenced the worldwide use of (l.-r.) Richard Goldstein, M.D., Ph.D., John L. Tarpley, M.D., Sunil Geevarghese, M.D., R. Daniel Beauchamp, M.D., with Scott family Liz and Art McWilliams and Sue and Bill Scott, III. anesthesia in surgery in a Chain and Heatley et al. discovered matter of just three weeks. penicillin, which was not produced in In 1867, Sir Joseph Lister published a real quantity until World War II. Florey, paper advocating the use of antiseptics to Chain and Fleming received the Nobel sterilize surgical instruments and clean Prize in 1945 for their work on penicillin wounds to prevent the spread of infecand the introduction of antibiotics. tion during operations. These advances, half of which occurred Though his efforts ultimately led to the well after the first medical degree was use of antisepsis and antiseptics during conferred at Vanderbilt in 1874, changed operative procedures and in the treatboth surgery and surgery education ment of wounds and injuries, a 20-year in ways that still impact surgeons and debate ensued on the necessity of “Lister- residents today. ism.” German surgeons were the first to Perhaps future innovations being embrace antisepsis as early as 1875. explored today, including personalized In 1895, Wilhelm Conrad Roentgen medicine, robotic surgery, and regenerabecame the father of imaging when tive medicine and tissue engineering, he took the first x-ray, an image of his will too become known as foundational wife’s hand. From this pioneering effort discoveries in the continued evolution of was born CTs, PET scans and MRIs. surgery. In 1901, Roentgen won the first Nobel The First Annual Scott Society Lecture Prize for his work in this area. was sponsored by Vanderbilt University At the same time, Karl Landsteiner, an Medical Alumni Affairs, under the direcAustrian biologist and physician led the tion of Associate Dean Ann Price, M.D. world to the next scientific achievement The standing-room only event was part that would forever change surgery. From of the 2012 Vanderbilt Medical Alumni his discovery of the major blood types, Reunion. the process of transfusion was born in The H. William Scott, Jr. Society Lecthe first decade of the 20th century. ture in Surgical History will take place And finally, in 1929, Sir Alexander annually to commemorate the seminal Fleming, a surgeon, published his obser- contributions of Dr. Scott to Vanderbilt’s vations on the mold penicillium notatum. ongoing leadership in surgical excellence, A few years later in the 1930s, Florey, clinical care, teaching and research. r