Postgraduate Seminar
Thursday 12th July, room 564, 5pm
Reverse Monte Carlo Modelling of GeO2 Glass
Robin Orman
Germania is one of the three most-studied
systems in glass science, but still the
differences between its structure and that of
silica glass have not been definitively
discriminated. This talk will present neutron
and high-energy X-ray diffraction data of
vitreous GeO2 that have been modelled with a
Reverse Monte Carlo technique, and from the
results the relationship to the structure of SiO2
and the First Sharp Diffraction Peak will be
discussed.
Structural determination of Membrane Proteins by Solid-State NMR
Amy Webber
Determining the three-dimensional structure of biological molecules such as
proteins is a key step to understanding their function and their role in disease
mechanisms.
Despite their relevance in structural
biology, less than 100 membrane
proteins structures have been solved
as compared to 30,000 for soluble
proteins. The solid-state NMR
methodology is hence applied to
probe membrane protein structures in
their natural lipid environment, via a
combination of Double Quantum
filtration and two dimensional
experiments to determine throughspace and bonding arrangements.
The postgraduate seminar series is a series of informal talks run by
postgraduates for postgraduates. All postgraduates are welcome and
refreshments are always provided!