Product datasheet
Anti-CD36 antibody [SMomega] ab77145
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Overview
Product name
Anti-CD36 antibody [SMomega]
Description
Mouse monoclonal [SMomega] to CD36
Tested applications
IHC-Fr, Neutralising, Flow Cyt
Species reactivity
Reacts with: Human
Immunogen
Tissue/ cell preparation (Human): Tonsil cells and PBM.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw
cycles.
Storage buffer
Preservative: None
Constituents: PBS
Purity
Size exclusion
Clonality
Monoclonal
Clone number
SMomega
Myeloma
NS1/1-Ag4-1
Isotype
IgM
Applications
Our Abpromise guarantee covers the use of ab77145 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application
Abreviews
Notes
IHC-Fr
Use at an assay dependent concentration.
Neutralising
Use at an assay dependent concentration.
Flow Cyt
Use at an assay dependent concentration. ab91545-Mouse monoclonal IgM, is
suitable for use as an isotype control with this antibody.
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Target
Function
Seems to have numerous potential physiological functions. Binds to collagen, thrombospondin,
anionic phospholipids and oxidized LDL. May function as a cell adhesion molecule. Directly
mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Binds long chain
fatty acids and may function in the transport and/or as a regulator of fatty acid transport.
Receptor for thombospondins, THBS1 AND THBS2, mediating their antiangiogenic efects.
Involvement in disease
Defects in CD36 are the cause of platelet glycoprotein IV deficiency (PG4D)[MIM:608404]; also
known as CD36 deficiency. Platelet glycoprotein IV deficiency can be divided into 2 subgroups.
The type I phenotype is characterized by platelets and monocytes/macrophages exhibiting
complete CD36 deficiency. The type II phenotype lacks the surface expression of CD36 in
platelets, but expression in monocytes/macrophages is near normal.
Genetic variations in CD36 are associated with susceptibility to coronary heart disease type 7
(CHDS7) [MIM:610938].
Sequence similarities
Belongs to the CD36 family.
Post-translational
modifications
N-glycosylated and O-glycosylated with a ratio of 2:1.
Cellular localization
Membrane.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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Terms and conditions
Guarantee only valid for products bought direct from Abcam or one of our authorized distributors
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