Doctor Seble Wagaw Abbvie Drug Substance Control and Strategy Development Thursday November 5th, 2015 11:00 am Room 1315 Chemistry The development of a control strategy for a commercial drug substance manufacturing process is built by correlating the attributes of the drug that are important to the patient to the manufacturing conditions. Emphasis is placed on developing a deep understanding of the impact that reaction chemistry and processing conditions has on the quality of the product. Various approaches to developing this understanding will be described, with an emphasis on the use of multivariate experimental approaches.